A Phase 1/2 interventional study of electroacupuncture in Reperfusion Injury, sponsored by Shengjing Hospital. Suspended at 1 site in China. Open to female participants aged 18 Years to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2016-08-01.
Sponsored by Shengjing Hospital · Phase 1/2, Interventional, and Prevention
TEAS might protect against postoperative pulmonary such as ischemia-reperfusion injury (IRI) and atelectasis. We tested the hypothesis that transcutaneous electrical acupoint stimulation protects against postoperative pulmonary complications in patients who are receiving mechanical ventilation during general anesthesia for gynecologic laparoscopic surgery.
Participants: 100 patients who underwent elective gynecologic laparoscopic surgery Methods: We recruited 100 patients who are planned for gynecologic laparoscopic surgery. Patients were enrolled from March 1, 2015. We randomly allocated patients into two groups: controlled group ( patients treated without transcutaneous electrical acupoint stimulation) and TEAS group (patients treated with TEAS on Feishu, Hegu, Chize half an hour before the surgery). Blood pH, Pco2, Po2 and oxygen saturation were measured by an automatic blood gas analyzer immediately after obtaining the samples from the aorta. Sample all the patients blood before and after the surgery. And then measure the level of TNF-α, IL-1β, and IL-6.
271 studies on the registry are indexed under Reperfusion Injury; 42 are open to participants now.
This study's planned enrollment of 100 is above the median of 61 across 215 interventional studies indexed under Reperfusion Injury.
Browse Reperfusion Injury studies →Shengjing Hospital is the lead sponsor of 124 studies on the registry; 57 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Before anesthesia, patients in this group treated with Transcutaneous Electric Acupoint Stimulation (TEAS) which is an electroacupuncture on Feishu, Hegu, Chize half an hour before the surgery, using the device Hua Tuo SDZ-II Acupoint Stimulator. The stimulus parameters set as 2/100Hz, 2V, 30min.
Device: electroacupuncture
Patients in controlled group treated without TEAS or other placebo.
Transcutaneous Electric Acupoint Stimulation which is a device of electroacupuncture was used on patients in TEAS group with the stimulator parameters set as 2/100Hz, 2V, 30min.
the change of hemodynamic parameter MAP in mmHg
Time frame: intraoperative
the change of hemodynamic parameters HR in beat per minutes
Time frame: intraoperative
the change of blood SPO2 in percentage
Time frame: intraoperative
the change of blood pH
Time frame: intraoperative
the change of blood PCO2 in mmHg
Time frame: intraoperative
the change of blood PO2 in mmHg
Time frame: intraoperative
the change of Plasma concentration of TNF-α in pg/mL
Time frame: intraoperative
post-operative pulmonary complications
Time frame: in the first 5 days after surgery
the change of plasma concentration of IL-1β
Time frame: intraoperative
This study is suspended, as verified in Jul 2016. You cannot join it, but the record below documents what was studied.
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Shengjing Hospital