An observational study in Multiple Sclerosis, sponsored by Duke University. Completed at 1 site in United States. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2022-04-20.
Sponsored by Duke University · Observational
The purpose of this study is to better characterize the fluctuations in multiple sclerosis symptoms and their relationship to medications, to length/extent of disease, and to a variety of physiologic measures.
3,460 studies on the registry are indexed under Multiple Sclerosis; 661 are open to participants now.
This study's enrollment of 2,200 is above the median of 100 across 1,016 observational studies indexed under Multiple Sclerosis.
Browse Multiple Sclerosis studies →Duke University is the lead sponsor of 2,025 studies on the registry; 275 are open to participants now.
Of its 194 completed or terminated interventional studies of FDA-regulated products, 159 (82%) have results posted.
Counted across the registry records on this site, refreshed daily.
Study subjects will be self-selecting from the national release of a mobile application.
Exclusion Criteria:
Those who document during the study on-boarding process that they suffer from relapsing-remitting multiple sclerosis.
Other: Personal history of multiple sclerosis
This who document during the on-boarding process that they suffer from primary progressive multiple sclerosis.
Other: Personal history of multiple sclerosis
This who document during the on-boarding process that they suffer from secondary progressive multiple sclerosis.
Other: Personal history of multiple sclerosis
This who document during the on-boarding process that they do not suffer from multiple sclerosis.
Other: Personal history of multiple sclerosis
Participants will be stratified into one of four cohorts based on their experience (or lack of experience) with the three major forms of multiple sclerosis.
Change in perceived fatigue severity (self-report) as recorded by symptom diary
Time frame: Every 24 hours through study completion, an average of 6 months
Change in perceived cognitive impairment (self-report) as recorded by symptom diary
Severity of cognitive impairment experienced from multiple sclerosis
Time frame: Every 24 hours through study completion, an average of 6 months
Change in perceived depression or anxiety severity (self-report) as recorded by symptom diary
Severity of any mood disorders experienced from multiple sclerosis
Time frame: Every 24 hours through study completion, an average of 6 months
Change in perceived walking instability (self-report) as recorded by symptom diary
Time frame: Every 24 hours through study completion, an average of 6 months
Change in perceived vision difficulties (self-report) as recorded by symptom diary
Time frame: Every 24 hours through study completion, an average of 6 months
Change in perceived Bowel/Bladder dysfunction (self-report) as recorded by symptom diary
Severity of bowel/bladder dysfunction experienced from multiple sclerosis
Time frame: Every 24 hours through study completion, an average of 6 months
Change in perceived sensory disturbance (self-report) as recorded by symptom diary
Time frame: Every 24 hours through study completion, an average of 6 months
Change in perceived vertigo severity (self-report) as recorded by symptom diary
Time frame: Every 24 hours through study completion, an average of 6 months
Change in perceived dysarthria severity (self-report) as recorded by symptom diary
Time frame: Every 24 hours through study completion, an average of 6 months
Change in pain (self-report) as recorded by symptom diary
Time frame: Every 24 hours through study completion, an average of 6 months
Change in sleep quality as recorded by app-linked wearable device
Time frame: Every 24 hours through study completion, an average of 6 months
Change in medication adherence (self-report) as recorded by medication diary
Time frame: Every 24 hours through study completion, an average of 6 months
Change in self-efficacy (self-report) as determined by the Multiple Sclerosis self-efficacy scale (survey instrument)
Time frame: every three months, through study completion (an average of 6 months)
Change in Multiple Sclerosis Quality of Life Inventory
The Multiple Sclerosis Quality of Life Inventory surveys are prompted based on the app user's responses on the daily surveys.
Time frame: prompted based on the app user's responses on the daily surveys, up to 6 months
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in Apr 2022. You cannot join it, but the record below documents what was studied.
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Duke University