An interventional study of Cefotiam in Gastric Varices and Cirrhosis, sponsored by Shanghai Zhongshan Hospital. Status unknown at 1 site in China. Open to participants aged 18 Years to 75 Years. Per ClinicalTrials.gov, last updated 2017-01-06.
Sponsored by Shanghai Zhongshan Hospital · Not applicable, Interventional, and Prevention
The purpose of the study is to assess the efficiency and safety of prophylactic use of antibiotics in endoscopic injection of tissue adhesive in gastric varices.
At present, there is still a controversy about the application of antibiotics in the treatment of patients with non acute hemorrhage of esophageal varices. This study is a randomized controlled trial. Patients randomly enter two treatment groups:
the prophylactic use of antibiotics group
and
Treatment allocation is by block randomization with an equal number for both groups. The incidence of infection after endoscopic treatment will be analyzed.
171 studies on the registry are indexed under Esophageal and Gastric Varices; 41 are open to participants now.
This study's planned enrollment of 120 is above the median of 107 across 110 interventional studies indexed under Esophageal and Gastric Varices.
Browse Esophageal and Gastric Varices studies →Shanghai Zhongshan Hospital is the lead sponsor of 648 studies on the registry; 289 are open to participants now.
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Exclusion Criteria:
Half an hour before endoscopic treatment, cefotiam 2.0g intravenous
Drug: Cefotiam
Routine endoscopic examination and treatment. Antibiotics are not used before endoscopic treatment
Prophylactic use of antibiotics group: Half an hour before endoscopic treatment, cefotiam 2.0g intravenous
Also known as: HaiTiShu
The incidence of infection after endoscopic treatment
Patients will receive body temperature, blood routine, inflammatory markers examination before and after endoscopic treatment.
Time frame: 1 week
Rebleeding rate
Patients will receive an endoscopic examination after patients have been followed up for 2 months.
Time frame: 2 months
Mortality rate
The investigators observe the mortality events during 2 months
Time frame: 2 months
This study is status unknown, as verified in Jan 2017. You cannot join it, but the record below documents what was studied.
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Esophageal and Gastric Varices →