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CompletedNCT02667509Updated Apr 14, 2016

The Evolutionary Model of Mild-to-moderate Myopia in China

An observational study in Refractive Error, sponsored by Sun Yat-sen University. Completed at 1 site in China. Per ClinicalTrials.gov, last updated 2016-04-14.

Sponsored by Sun Yat-sen University · Observational

Study type
Observational
Time perspective
Cross-sectional
Enrollment
852,441
Sex
All
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Study summary

Myopia has emerged as a major health issue in east Asia, because of its increasingly high prevalence in the past few decades (now 80-90% in school-leavers), and because of the sight-threatening pathologies associated with high myopia, which now aff ects 10-20% of those completing secondary schooling in this part of the world. Similar, but less marked, changes are occurring in other parts of the world. The higher prevalence of myopia in east Asian cities seems to be associated with increasing educational pressures, combined with life-style changes, which have reduced the time children spend outside.

Read the detailed description

Myopia has emerged as a major health issue in east Asia, because of its increasingly high prevalence in the past few decades (now 80-90% in school-leavers), and because of the sight-threatening pathologies associated with high myopia, which now aff ects 10-20% of those completing secondary schooling in this part of the world. Similar, but less marked, changes are occurring in other parts of the world. The higher prevalence of myopia in east Asian cities seems to be associated with increasing educational pressures, combined with life-style changes, which have reduced the time children spend outside.

In this trial, the investigators aim to study the evolutionary model of myopia in China, which could provide new insight into the social development and human adaptation.

02

Conditions studied

  • Refractive Error

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Keywords

  • Evolutionary Model
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In context

Refractive Errors

427 studies on the registry are indexed under Refractive Errors; 62 are open to participants now.

This study's enrollment of 852,441 is above the median of 150 across 110 observational studies indexed under Refractive Errors.

Browse Refractive Errors studies →

Lead sponsor

Sun Yat-sen University is the lead sponsor of 1,681 studies on the registry; 610 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Probability sample

Study population

Subjects from all the province of China who undergoing the examination of Refractive error from 2005 to 2015 year.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Patients complete the examination of Refractive error from 2005 to 2015 year.

Exclusion criteria

Exclusion Criteria:

  • Patients could not complete the examination of Refractive error
05

Study design

Time perspective
Cross-sectional
Enrollment
852,441 participants (actual)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. Refractive error of both eyes measured by autorefractor and subjective measuring

    Time frame: Baseline

07

Study locations

1 site
  • Zhongshan Ophthalmic Center, Sun Yat-sen University
    Guangzhou, Guangdong 510060, China
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References and documents

Publications

  • Morgan IG, Ohno-Matsui K, Saw SM. Myopia. Lancet. 2012 May 5;379(9827):1739-48. doi: 10.1016/S0140-6736(12)60272-4. PubMed 22559900 ↗
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Apr 14, 2016, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT02667509
Collaborators
Ministry of Health, China
Responsible party
Erping Long (Principal Investigator, Home for Cataract Children, Zhongshan Ophthalmic Center, Sun Yat-sen University) — Principal investigator
First posted
Jan 29, 2016
Start date
Jan 2005
Primary completion
Oct 2015
Completion
Oct 2015
Last update
Apr 14, 2016

Study contacts

Haotian Lin Lin, M.D., Ph.D
study director · Zhongshan Ophthalmic Center, Sun Yat-sen University
Yizhi Liu, M.D., Ph.D
study chair · Zhongshan Ophthalmic Center, Sun Yat-sen University
Erping Long, M.D., Ph.D
principal investigator · Zhongshan Ophthalmic Center, Sun Yat-sen University

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Apr 2016. You cannot join it, but the record below documents what was studied.

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