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Status unknownNCT02626806EUROCADUpdated Dec 10, 2015

Exercise-induced High-sensitivity Troponin Levels as a Predictor for Obstructive Coronary Artery Disease

An observational study in Coronary Artery Disease, sponsored by Universitaire Ziekenhuizen KU Leuven. Status unknown at 1 site in Belgium. Open to participants aged 18 Years to 99 Years. Per ClinicalTrials.gov, last updated 2015-12-10.

Sponsored by Universitaire Ziekenhuizen KU Leuven · Observational

The sponsor has not verified this record recently (last verified Dec 2015), so the status shown — last known as Recruiting — may be out of date.
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
150
Ages
18 Years to 99 Years
Sex
All
01

Study summary

  1. To compare hs-TnT levels after a cardiac stress test in patients with vs. patients without CAD
  2. To assess the level of post-exercise hs-TnT predicting CAD (using ROC-analysis)
  3. To determine the sensitivity, specificity and accuracy of this exercise-induced hsTopT level in predicting CAD, either alone or in relation to traditional patient-related and exercise test-related metrics
02

Conditions studied

  • Coronary Artery Disease

Keywords

  • exercise test
  • HS -troponin
  • Coronary artery disease
03

In context

Coronary Artery Disease

5,600 studies on the registry are indexed under Coronary Artery Disease; 958 are open to participants now.

This study's planned enrollment of 150 is below the median of 336 across 1,947 observational studies indexed under Coronary Artery Disease.

Browse Coronary Artery Disease studies →

Lead sponsor

Universitaire Ziekenhuizen KU Leuven is the lead sponsor of 928 studies on the registry; 261 are open to participants now.

Of its 5 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 99 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

To compare hs-TnT levels after a cardiac stress test in patients with vs. patients without CAD

Inclusion criteria

  1. Patients with suspected CAD, planned for diagnostic coronary angiogram
  2. Patients with previous revascularization, suspected of recurrent ischemia

Exclusion criteria

Exclusion Criteria:

  1. Congestive cardiomyopathy with LV EF \< 35%
  2. Renal failure with eGFR \< 30 ml/min
  3. Known structural or severe valvular heart disease
  4. Prior CABG
  5. Previous ACS \< 6 weeks
  6. Known incomplete revascularization after previous PCI
  7. Unstable angina or ACS (defined as unstable anginal symptoms + ECG changes or hs-TnT > 0.053 ng/L)
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
150 participants (estimated)
Patient registry
No
Biospecimen retention
Samples without dna

Groups and cohorts

  • patients with hemodynamic significant CAD;
  • patients without hemodynamic significant CAD
06

What researchers measure

Primary outcomes

  1. Presence of coronary artery stenosis more than 50%

    Time frame: 24 hours

07

Study locations

1 of 1 sites recruiting
  • UZLeuven
    Leuven, 3000, Belgium
    • Marina Claes, bachelor nurse · Contact · marina.claes@uzleuven.be · 003216342461
    • Dries De Cock, MD · Contact · dries.decock@uzleuven.be · 003216341519
    • Walter Desmet, MD, PhD · Principal investigator
    • Christophe Dubois, MD, PhD · Sub investigator
    • Tom Adriaenssens, MD, PhD · Sub investigator
    • Peter Sinnaeve, MD, PhD · Sub investigator
    • Johan R Bennett, MD · Sub investigator
    • Dries De Cock, MD · Sub investigator
    • Nick Hiltrop, MD · Sub investigator
    Recruiting
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 10, 2015, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT02626806
Lead sponsor
Universitaire Ziekenhuizen KU Leuven
Responsible party
Prof Dr Walter Desmet (Head of Clinic, Interventional Cardiology, Universitaire Ziekenhuizen KU Leuven) — Principal investigator
First posted
Dec 10, 2015
Start date
Nov 2013
Primary completion
Jun 2016 (estimated)
Last update
Dec 10, 2015

Study contacts

Dries De Cock, MD
Contact
dries.decock@uzleuven.be
003216341519
Nick Hiltrop, MD
Contact
nick.hiltrop@uzleuven.be
003216344235

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Dec 2015. You cannot join it, but the record below documents what was studied.

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