CClinicalTrials.gg
CompletedNCT02517723Updated Oct 8, 2021

Narrative Exposure Therapy in Women With Borderline Personality Disorder and Posttraumatic Stress Disorder

An interventional study of Narrative Exposure Therapy and Dialectical Behavior Therapy in Borderline Personality Disorder and Stress Disorders, Post-Traumatic, sponsored by Evangelisches Krankenhaus Bielefeld gGmbH. Completed at 1 site in Germany. Open to female participants aged 18 Years to 65 Years. Per ClinicalTrials.gov, last updated 2021-10-08.

Sponsored by Evangelisches Krankenhaus Bielefeld gGmbH · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
67
Allocation
Randomized
Ages
18 Years to 65 Years
Sex
Female
01

Study summary

Narrative Exposure Therapy (NET) is an evidence-based trauma-focussed treatment, suitable for survivors of prolonged and repeated exposure to traumatic stress and childhood adversity. Patients with Borderline Personality Disorder (BPD) often suffer from a comorbid Posttraumatic Stress Disorder (PTSD) caused by multiple traumatic events. Therapeutic aims are the reduction of PTSD-Symptoms in these patients via activation of associative neural networks related to traumatic experiences and habituation of fear and the placement of traumatic experiences in a reconstructed, detailed and consistent autobiography. This practice enables the processing of and coping with painful memories and the construction of clear contingencies of dangerous and safe conditions, generally leading to significant emotional recovery. The investigators assume that using NET the reduction of PTSD symptom severity is greater compared to treatment by Dialectical-Behavioral Therapy (DBT).

02

Conditions studied

  • Borderline Personality Disorder
  • Stress Disorders, Post-Traumatic

Keywords

  • Borderline Personality Disorder
  • comorbid Posttraumatic Stress Disorder
  • Narrative Exposure Therapy
  • Dialectical-Behavioral Therapy
03

In context

Stress Disorders, Traumatic

1,148 studies on the registry are indexed under Stress Disorders, Traumatic; 108 are open to participants now.

This study's enrollment of 67 is above the median of 60 across 909 interventional studies indexed under Stress Disorders, Traumatic.

Browse Stress Disorders, Traumatic studies →

Lead sponsor

Evangelisches Krankenhaus Bielefeld gGmbH is the lead sponsor of 4 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 65 Years
Sexes eligible
Female
Accepts healthy volunteers
No

Inclusion criteria

  • age ≥ 18 years
  • DSM-IV-TR diagnoses of BPD and PTSD
  • legal competence
  • none or stable medication
  • illegal drug abstinence for at least the last 6 months
  • capacity to consent and contract

Exclusion criteria

Exclusion Criteria:

  • other severe mental disorders (e.g., bipolar disorder, acute psychosis)
  • simultaneous consumption of drugs
  • simultaneous participation in other treatment-studies
  • pregnancy or breastfeeding
  • lack of capability to negotiate a no-suicide agreement
  • suicide attempt or attempts during the 8 weeks prior to start of treatment
  • perpetrator-contact
  • Body Mass Index (BMI) \< 16
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Factorial assignment
Masking
Single (Outcomes assessor)
Enrollment
67 participants (actual)

Study arms

  • Experimental
    SIC + NET

    Waiting List + Standard Inpatient Care + Narrative Exposure Therapy

    Behavioral: Narrative Exposure Therapy · Behavioral: Standard Inpatient Care · Other: Waiting List

  • Active comparator
    SIC + DBT

    Waiting List + Standard Inpatient Care + Dialectical Behavior Therapy

    Behavioral: Dialectical Behavior Therapy · Behavioral: Standard Inpatient Care · Other: Waiting List

Interventions

  • BehavioralNarrative Exposure Therapy

    Narrative Exposure Therapy (NET) is based on Testimony Therapy in combination with cognitive behavioural exposure techniques and elements of client-centered counselling. The clients can restore their autobiographic memories about their traumatic experiences. In this way fragmentary memories are transformed into a coherent narrative structure. This practice enables the processing of painful emotions and the construction of clear contingencies of dangerous and safe conditions, generally leading to significant emotional recovery. Therapeutic aims are the reduction of PTSD-Symptomload via activation of fear-network and habituation of fear and the placement of traumatic experiences in a reconstructed, detailed and consistent autobiography. NET will be applied in eight sessions (90-120min/session) in a standardized, manualized manner.

    Also known as: NET

  • BehavioralDialectical Behavior Therapy

    Dialectical behavior therapy is a cognitive behavioral treatment program developed by Marsha Linehan to treat suicidal clients meeting criteria for BPD. It directly targets suicidal behavior, behaviors that interfere with treatment delivery, and other dangerous, severe, or destabilizing behaviors. Via standard DBT patients improve behavioral capabilities, motivation for skillful behavior, generalization of gains to the natural environment, structuring the treatment environment so that it reinforces functional rather than dysfunctional behaviors. It also targets the therapist capabilities and motivation to treat patients effectively. Patients get weekly individual psychotherapy (1 h/wk), group skills training (3.75 h/wk), a weekly therapist consultation team meetings.

    Also known as: DBT

  • BehavioralStandard Inpatient Care

    Unspecific group therapy that is identical in both groups (music therapy etc.)

    Also known as: SIC

  • OtherWaiting List

    Treatment as usual in the community (no DBT, no exposure of trauma memories)

06

What researchers measure

Primary outcomes

  1. Change from first investigation in Posttraumatic Symptom Severity at 18 months (Clinician-Administered PTSD Scale; CAPS)

    Time frame: first investigation (t1), after waiting list (3 months, t2), directly after therapy (3 months, t1), 1 year after therapy (15 months, t3)

Secondary outcomes

  1. Change from first investigation in Borderline Symptome Severity at 18 months(Borderline Symptom Liste; BSL)

    Time frame: first investigation (t1), after waiting list (3 months, t2), directly after therapy (6 months, t3), 1 year after therapy (18 months, t4)

  2. Change from first investigation in Severity of Dissociative Symptoms at 18 months (Fragebogen zu Dissoziativen Symptome ;FDS)

    Time frame: first investigation (t1), after waiting list (3 months, t2), directly after therapy (6 months, t3), 1 year after therapy (18 months, t4)

  3. Change from first investigation in Severity of Depressive Symptoms at 18 months (Becks Depressions Inventar II, BDI-II)

    Time frame: first investigation (t1), after waiting list (3 months, t2), directly after therapy (6 months, t3), 1 year after therapy (18 months, t4)

  4. Change from first investigation in Quality of Life at 12 months (WHO-Qualitiy of Life; WHOQOL)

    Time frame: first investigation (t1), after waiting list (3 months, t2), directly after therapy (6 months, t3), 1 year after therapy (18 months, t4)

07

Study locations

1 site
  • Clinic of Psychiatry, Evangelisches Krankenhaus Bielefeld
    Bielefeld, 33617, Germany
08

References and documents

Publications

  • Steuwe C, Berg M, Beblo T, Driessen M. Narrative Exposure Therapy in Patients With Posttraumatic Stress Disorder and Borderline Personality Disorder in a Naturalistic Residential Setting: A Randomized Controlled Trial. Front Psychiatry. 2021 Nov 26;12:765348. doi: 10.3389/fpsyt.2021.765348. eCollection 2021. PubMed 34899426 ↗
  • Storebo OJ, Stoffers-Winterling JM, Vollm BA, Kongerslev MT, Mattivi JT, Jorgensen MS, Faltinsen E, Todorovac A, Sales CP, Callesen HE, Lieb K, Simonsen E. Psychological therapies for people with borderline personality disorder. Cochrane Database Syst Rev. 2020 May 4;5(5):CD012955. doi: 10.1002/14651858.CD012955.pub2. PubMed 32368793 ↗
  • Steuwe C, Rullkotter N, Ertl V, Berg M, Neuner F, Beblo T, Driessen M. Effectiveness and feasibility of Narrative Exposure Therapy (NET) in patients with borderline personality disorder and posttraumatic stress disorder - a pilot study. BMC Psychiatry. 2016 Jul 20;16:254. doi: 10.1186/s12888-016-0969-4. PubMed 27439618 ↗
09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Oct 8, 2021, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT02517723
Lead sponsor
Evangelisches Krankenhaus Bielefeld gGmbH
Responsible party
Prof. Dr. med. Martin Driessen (Martin Driessen, Prof. Dr. med., Evangelisches Krankenhaus Bielefeld gGmbH) — Principal investigator
First posted
Aug 7, 2015
Start date
Apr 2014
Primary completion
Jan 31, 2020
Completion
Jan 31, 2020
Last update
Oct 8, 2021

Study contacts

Carolin Steuwe, M.Sc.
study director · Clinic of Psychiatry, Evangelisches Krankenhaus Bielefeld
Martin Driessen, Prof. Dr. med.
principal investigator · Clinic of Psychiatry, Evangelisches Krankenhaus Bielefeld
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Oct 2021. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion