An observational study in Metabolic Myopathies, Exercise Test and Myalgia, sponsored by University Hospital, Brest. Recruiting at 1 site in France. Open to participants aged 5 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2020-01-22.
Sponsored by University Hospital, Brest · Observational
Exertional symptoms are the hallmarks of metabolic myopathies, supporting the concept of using functional tests when this diagnosis is suspected. Exercise increases the concentration of muscle metabolites in the venous blood supply (e.g. lactate, pyruvate, and ammonia) especially during recovery. The purpose of this study is to compare the results of exercise testing with to the data from muscle biopsy or genetic analysis.
256 studies on the registry are indexed under Myalgia; 46 are open to participants now.
This study's planned enrollment of 1,000 is above the median of 196 across 35 observational studies indexed under Myalgia.
Browse Myalgia studies →University Hospital, Brest is the lead sponsor of 601 studies on the registry; 136 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Subjects referred to perform a metabolic exercise testing.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Contraindication
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
All the subjects referred to performed a metabolic exercise testing.
Device: functional test · Genetic: matching genotype with phenotype
subjects perform a metabolic exercise testing
Whole-body dynamic exercise
The relation between Cardiopulmonary exercise test variables and the results of muscle biopsy or genetic analysis will be evaluated.
Time frame: Participants will be followed for an expected average of 1 year to determine whether a muscle biopsy is performed
Grip-test
The relation between Grip-test variables and the results of muscle biopsy or genetic analysis will be evaluated.
Time frame: Participants will be followed for an expected average of 1 year to determine whether a muscle biopsy is performed
Blood tests
The results of blood analysis from samples performed before, during, and after exercise will be compared to the results of muscle biopsy or genetic analysis.
Time frame: Participants will be followed for an expected average of 1 year to determine whether a muscle biopsy is performed
The record gives a start of Sep 2008, a primary completion of Dec 2027 and a completion of Dec 2027. It does not say whether these dates are actual or estimated.
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