A Phase 2 interventional study of Integrated Care Group and Standard Care Group in Periodontitis and Coronary Disease, sponsored by Macmillan Research Group UK. Completed at 1 site in India. Open to participants aged 18 Years to 60 Years. Per ClinicalTrials.gov, last updated 2014-03-07.
Sponsored by Macmillan Research Group UK · Phase 2, Interventional, and Prevention
Cardiovascular diseases (CVD) are still considered the main cause of mortality and morbidity all over the world. In the last years, efforts have been made to define more effective therapeutic and preventive strategies.Periodontal diseases have been considered a probable risk factor for CVD with a great amount of evidence from observational studies. Although there are some interventional studies evaluating the systemic effects of periodontal therapy, there is little information regarding the impact of periodontal treatment on the prevention of cardiovascular events. To the best of our knowledge, there are no randomized controlled trials published to date assessing the effect of periodontal therapy in primary prevention of CVD.
1,635 studies on the registry are indexed under Periodontitis; 327 are open to participants now.
This study's enrollment of 57 is above the median of 45 across 1,191 interventional studies indexed under Periodontitis.
Browse Periodontitis studies →Macmillan Research Group UK is the lead sponsor of 9 studies on the registry; none are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Dental therapist providing standard periodontal treatment
Other: Standard Care Group
a combined treatment approach of Dental Therapist, Dental Hygienist, Cardiologist along with counselor
Behavioral: Integrated Care Group
The group (TG) consisted of periodontal treatment comprising one session of supragingival scaling and personalized oral hygiene instructions, followed by one to four sessions of subgingival scaling and root planing (SRP) by quadrant, under local anesthesia, in a period of 14 days. Individuals were be followed monthly during the first 6 months. In the follow-up sessions, professional plaque removal, oral hygiene instructions, cardiac support along with counseling reinforcement were be provided.
The group (TG) comprising one session of supragingival scaling followed by one to four sessions of subgingival scaling and root planing (SRP) by quadrant, under local anesthesia, in a period of 14 days.
Traditional cardiovascular risk markers (total cholesterol, LDL-C, HDL-C and triglycerides)
Time frame: Change from baseline to six month
High- and low-density lipoprotein cholesterol
Time frame: Change from baseline to six month
cardiovascular risk scores (Framingham)
Time frame: Change from baseline to six months
Blood Pressure and Sugar
Time frame: Change from baseline to six months
This study is completed, as verified in Mar 2014. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Macmillan Research Group UK