An interventional study of Optiflow in Hypoxemia, sponsored by Cliniques universitaires Saint-Luc- Université Catholique de Louvain. Completed. Open to participants aged 18 Years to 90 Years. Per ClinicalTrials.gov, last updated 2016-02-01.
Sponsored by Cliniques universitaires Saint-Luc- Université Catholique de Louvain · Not applicable, Interventional, and Supportive care
Patients with respiratory failure often need oxygen and/or ventilatory support. Patients who need only oxygen support, usually received low flow oxygen (\< 15 Liters / min), as well as in respiratory weaning. Now new devices can be used. They provide high flow oxygen with different benefits. This high flow devices provide exact fraction of inspired oxygen (FiO2), allows a positive end expiratory pressure and supplies a wash out flow. The hypothesis of this study is that the high flow oxygen enable more efficient oxygen administration than conventional oxygen. In addition, it would improve the effectiveness of the ventilation of the patient, through flushing the dead space.
The investigators hypothesized that when using high flow oxygen therapy, respiratory failure is relieved, as well as ventilation failure, so accessories are less stressed muscles, and this can be demonstrated by the electromyography (EMG) of sterno-mastoid..
1,231 studies on the registry are indexed under Hypoxia; 241 are open to participants now.
This study's enrollment of 20 is below the median of 45 across 853 interventional studies indexed under Hypoxia.
Browse Hypoxia studies →Cliniques universitaires Saint-Luc- Université Catholique de Louvain is the lead sponsor of 342 studies on the registry; 61 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Inclusion Criteria: patients with respiratory failure.
Exclusion Criteria:
Patients receiving oxygen via high flow oxygen therapy (Optiflow)
Device: Optiflow
patients receiving oxygen via conventional way (low flow)
patients receive oxygen via high flow oxygen therapy during 20 minutes
Change from baseline in Oxygenation criteria
Arterial oxygen partial pressure (PO2), oxygen saturation by pulse oximetry (SpO2), arterial PO2/FiO2, positive end expiratory pressure (PEEP)
Time frame: 20 minutes
Change from baseline in Ventilation criteria
respiratory rate (RR), arterial partial CO2 pressure (PCO2), pH, sterno-mastoid EMG
Time frame: 20 minutes
change from baseline in hemodynamic criteria
cardiac frequency, arterial blood pressure
Time frame: 20 minutes
No study locations are listed for this record.
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in Jan 2016. You cannot join it, but the record below documents what was studied.
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Cliniques universitaires Saint-Luc- Université Catholique de Louvain