An interventional study of High-intensity interval training and Moderate intensity exercise training in Metabolic Dysfunction-associated Steatotic Liver Disease, sponsored by Cliniques universitaires Saint-Luc- Université Catholique de Louvain. Recruiting at 2 sites in Belgium. Open to participants aged 18 Years to 70 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-07-14.
Sponsored by Cliniques universitaires Saint-Luc- Université Catholique de Louvain · Not applicable, Interventional, and Treatment
Among 148 studies in Motor Activity with a site in Belgium — 40 open to participants now, 44 under way, none of them phase 3. Motor Activity · Belgium.
Among the 148 studies in Motor Activity with a site in Belgium, this one is the 58th largest by planned enrollment of the 117 interventional ones that give a count, is one of 11 that started in 2025, is one of 107 with no phase, reaches primary completion later than 31 of the 43 other live ones, and was the 122nd registered.
9,798 studies on the registry are indexed under Motor Activity; 1,910 are open to participants now.
Browse Motor Activity studies →40 of the 148 studies in Motor Activity with a site in Belgium are open now. Recruiting first, the newest first:
University Hospital, Ghent · Sites in Belgium
KU Leuven · Sites in Belgium
Vrije Universiteit Brussel · Sites in Belgium
De deyne Manon · Sites in Belgium
Groupe Hospitalier du Havre · Sites in Belgium, France
A study can be open while its sites in Belgium have not opened yet or have stopped. Only those recruiting at a site in Belgium →
Of the 1,201 Motor Activity studies recruiting now, 517 (43%) set no upper age limit and 535 (45%) stop at 75 or younger; 180 take children under 18; 420 take healthy volunteers.
This study: 18 Years to 70 Years · all sexes · healthy volunteers too.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
148 studies; the count open now beside each. This study's row is marked.
First in 2006; this study’s year is marked. 11 started in 2025.
By drug class, each counting the studies that test any of its medicines:
This study's planned enrollment of 60 is close to the median of 60 across 8,388 interventional studies indexed under Motor Activity.
Median enrollment 60 across the 117 interventional studies, 100 across the 31 observational. Of the 86 that completed or were terminated, 5 (6%) have results posted.
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7 of 148 have an industry lead sponsor. The 10 most frequent:
Cliniques universitaires Saint-Luc- Université Catholique de Louvain is the lead sponsor of 350 studies on the registry; 64 are open to participants now.
Cliniques universitaires Saint-Luc- Université Catholique de Louvain has 7 studies filed under Motor Activity — fewer than ten, so there is no comparison to draw.
11 of the studies in Motor Activity with a site in Belgium that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT05946109Universitair Ziekenhuis BrusselEffect of an Exercise Program for Frail Older Adults | 2026-11-30 |
| NCT07478224University Hospital, GhentAn Interventional Study to Evaluate the Impact of Blood Flow Restriction Training on Muscle, Bone, and Quality of Life in Adults With Osteogenesis Imperfecta Type I | 2026-12 |
| NCT04993482University Hospital, Ghent24-hour Movement Behaviors Among Type 2 Diabetes Mellitus Patients | 2026-12-01 |
| NCT06767930Université Catholique de LouvainEffects of HABIT-ILE in Adults with Bilateral Cerebral Palsy | 2026-12-31 |
| NCT07237893University of LiegeImpact of a Physical Activity Intervention on Cardiometabolic Health, Mental Health, and Lifestyle Factors. | 2027-01-01 |
Among the 148 studies in Motor Activity with a site in Belgium, from their registry updates:
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Muscle changes including myosteatosis are reported as highly prevalent in metabolic dysfunction-associated steatotic liver disease (MASLD). Recent studies highlighted a link between muscle fat content and liver disease severity. Conversely, MASLD histological remission though diet or metabolic surgeries is also linked to a decrease in muscle fat content. Therefore, skeletal muscle appears as a potential target to treat MASLD.
In this monocenter interventional study, we will assess the impact of physical activity on muscle fat content and liver disease severity in MASLD as well as the mechanisms mediating the potential beneficial effects of exercise.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Malignancy means cancer. Criteria about another or earlier malignancy ask whether you have had a different cancer, usually within a set number of years.
Some are commonly allowed, such as treated skin cancers other than melanoma and early cancers removed completely — check the exceptions this study lists.
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Cancer (malignancy)
Malignancy means cancer. Criteria about another or earlier malignancy ask whether you have had a different cancer, usually within a set number of years.
Some are commonly allowed, such as treated skin cancers other than melanoma and early cancers removed completely — check the exceptions this study lists.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Contraindication
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
in this control group, patients will perform non-cardiovascular non-intensity training (stretching, meditation).
Other: Low intensity exercise training
In this group, patients will perform moderate-intensity low interval training.
Other: Moderate intensity exercise training
In this group, patients willp erform high-intensity interval training.
Other: High-intensity interval training
High-intensity interval training
Moderate intensity exercise training
Low intensity exercise training
the impact of physical activity on muscle and liver phenotypes
the investigators will assess at baseline and every four weeks till study completion the impact of intervention on liver phenotype assessed by transient elastography and muscle phenotype assessed by MRI
Time frame: every four weeks from baseline till study completion
Plan to share: No
Started Sep 2025 (actual). Primary completion is estimated for Sep 2027, 24 months after the start.
Of 5,147 non-industry interventional studies with no phase under Motor Activity, half reached primary completion within 17 months of starting (the median), counting those still running; a quarter within 7 and three quarters within 36. This study's planned 24 months is above that.
Counting every sponsor, half of 5,207 studies reached it within 17 months; a quarter within 7 and three quarters within 36.
How these figures are worked out, and which studies are left out of them.
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Cliniques universitaires Saint-Luc- Université Catholique de Louvain →