A Phase 3 interventional study of Usual care follow-up by CRCDC and Information leaflet about colonoscopy follow-up in Colorectal Cancer Screening, sponsored by University Hospital, Caen. Recruiting at 1 site in France. Open to participants aged 50 Years to 75 Years. Per ClinicalTrials.gov, last updated 2026-09-18.
Sponsored by University Hospital, Caen · Phase 3, Interventional, and Screening
To be effective, organized colorectal cancer screening requires good adherence to diagnostic colonoscopy in the event of a positive test. In France, the rate of diagnostic colonoscopy following a positive colorectal cancer screening test is less than 85%, and the median delay is close to 90 days. After receiving their positive result from the laboratory, individuals with no known follow-up are contacted only six months later by the Regional Cancer Screening Coordination Centers (CRCDC) responsible for following up with individuals who have tested positive. To optimize follow-up with colonoscopy, earlier contact and information about colonoscopy appear to be necessary. The contribution of the general practitioner identified on the test could be an additional lever.
The SUIVICOLO study aims to evaluate the effectiveness on the rate of colonoscopies performed at 6 months of two strategies for optimizing the follow-up of positive results in comparison with control group C (current procedures of the CRCDC Centre Val de Loire without early letter).
The two strategies evaluated will be:
These strategies will be compared to the current follow-up strategy in a three arm randomized controlled arm.
6,541 studies on the registry are indexed under Colorectal Neoplasms; 1,667 are open to participants now.
This study's planned enrollment of 2,000 is above the median of 76 across 4,800 interventional studies indexed under Colorectal Neoplasms.
Browse Colorectal Neoplasms studies →University Hospital, Caen is the lead sponsor of 512 studies on the registry; 82 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Aged between 50 and 75 at the time of the positive colorectal cancer screening test
Exclusion Criteria:
Other: Usual care follow-up by CRCDC
B1
Other: Usual care follow-up by CRCDC · Other: Information leaflet about colonoscopy follow-up
B2
Other: Usual care follow-up by CRCDC · Other: Information leaflet about colonoscopy follow-up · Other: Endorsement of CRCDC letters from the GP
1. 6 months after positive test result: 1st reminder letter from the CRCDC if it has no information about a colonoscopy being performed 2. 12 months after positive test result: 2nd reminder letter from the CRCDC if it has no information about a colonoscopy being performed 3. 18 months after positive test result: 3rd reminder letter from the CRCDC if it has no information about a colonoscopy being performed
An information leaflet about colonoscopy follow-up will be sent in an early letter 7 days after positive test result, and though QR-codes in subsequent reminders.
Explicit mention of their general practitioner in letters and reminders sent by the CRCDC to individuals who have tested positive for colorectal cancer, including the information leaflet about colonoscopy or a link to this document (QR code).
Colonoscopy rate at 6 months after a positive test
Time frame: 6 months
Percentage of general practitioners who agreed to participate in the project
Time frame: At baseline
Colonoscopy rates at 12 months after a positive test
Time frame: 12 months
Colonoscopy rates at 18 months after a positive test
Time frame: 18 months
Colonoscopy rates at 24 months after a positive test
Time frame: 24 months
Number of reminders in each group by type of reminder
Time frame: 24 months
Number of people with contraindications to colonoscopy
Time frame: 24 months
Number of people with a CT colonography
Time frame: 24 months
Time to perform colonoscopy
Time frame: 24 months
Colorectal cancer at colonoscopy
Time frame: 24 months
Advanced neoplasia at colonoscopy
Time frame: 24 months
Number of people who refused colonoscopy
Time frame: 24 months
Number of lost to follow-up
Time frame: 24 months
Plan to share: No
No publications or documents are linked to this record.
Started Mar 2026 (actual). Primary completion is estimated for Mar 2027, 12 months after the start.
Of 106 non-industry phase 3 interventional studies under Colorectal Neoplasms, half reached primary completion within 65 months of starting (the median), counting those still running; a quarter within 42 and three quarters within 116. This study's planned 12 months is below that.
Counting every sponsor, half of 175 studies reached it within 50 months; a quarter within 35 and three quarters within 79.
How these figures are worked out, and which studies are left out of them.
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