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CompletedNCT01798420Updated Feb 25, 2013

Corticosteroids and Hemoglobin A1C Levels in Diabetic Patients With COPD Exacerbation

An observational study in Diabetes and Chronic Obstructive Pulmonary Disease, sponsored by The Nazareth Hospital, Israel. Completed at 1 site in Israel. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2013-02-25.

Sponsored by The Nazareth Hospital, Israel · Observational

Study type
Observational
Model
Case-control
Time perspective
Prospective
Enrollment
42
Ages
18 Years and older
Sex
All
01

Study summary

Corticosteroid treatment in diabetic patients admitted for COPD exacerbation are expected to significantly increase hemoglobin A1C levels

Read the detailed description

HbA1C levels were evaluated in diabetic patients with COPD exacerbation on admission to the hospital and 3-months later. Demographic, clinical, laboratory variables and total steroid dose were documented. Age- and sex-matched group of diabetic patients with COPD who were admitted for other reasons, were asked to participate as a control group. Mann-Whitney and Chi square/Fischer's exact tests were used to compare between the parameters of the two groups. Wilcoxon signed rank test was used to compare between HbA1C levels at baseline and 3 months later. Multi-variate linear regression analysis was used to find predictors for increase in HbA1C levels in the patients' group.

02

Conditions studied

  • Diabetes
  • Chronic Obstructive Pulmonary Disease

Keywords

  • COPD
  • Diabetes
  • steroids
  • Hemoglobin A1C DIFFERENCE
03

In context

Lung Diseases, Obstructive

2,592 studies on the registry are indexed under Lung Diseases, Obstructive; 198 are open to participants now.

This study's enrollment of 42 is below the median of 150 across 639 observational studies indexed under Lung Diseases, Obstructive.

Browse Lung Diseases, Obstructive studies →

Lead sponsor

The Nazareth Hospital, Israel is the lead sponsor of 6 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Diabetic patients with COPD ecaxerbation who are admitted to the hospital

Inclusion criteria

  • Diabetic patients with COPD exacerbation

Exclusion criteria

Exclusion Criteria:

  • Patients treated with steroids during the previous 3 months
05

Study design

Observational model
Case-control
Time perspective
Prospective
Enrollment
42 participants (actual)
Patient registry
No

Groups and cohorts

  • Corticosteroid
  • non-corticosteroid group
06

What researchers measure

Primary outcomes

  1. Hemoglobin A1C LEVEL

    Time frame: 3 MONTHS

Secondary outcomes

  1. Glucose levels

    Time frame: 3 months

Other outcomes

  1. Weight

    Time frame: 3 months

07

Study locations

1 site
  • Department of medicine
    Nzareth, Nazareth 16000, Israel
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 25, 2013, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT01798420
Lead sponsor
The Nazareth Hospital, Israel
Responsible party
George Habib (Head, Rheumatology clinic, Nzareth hospital, Nzareth, The Nazareth Hospital, Israel) — Principal investigator
First posted
Feb 25, 2013
Start date
Apr 2012
Primary completion
Sep 2012
Completion
Oct 2012
Last update
Feb 25, 2013

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Feb 2013. You cannot join it, but the record below documents what was studied.

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