An interventional study of Dexamethasone in Transient Tachypnea of the Newborn, sponsored by Ain Shams Maternity Hospital. Completed at 1 site in Egypt. Open to female participants aged 22 Years to 44 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2013-01-21.
Sponsored by Ain Shams Maternity Hospital · Not applicable, Interventional, and Prevention
Introduction: Babies born at term by elective caesarean section (CS) and before onset of labor are more likely to develop respiratory complications than babies born vaginally. In developing countries resources are scarce and it is difficult to provide expensive treatments as neonatal care.
Aim of the Work: To assess the effect of prophylactic dexamethasone administration before elective cesarean section at term in reducing neonatal respiratory complications.
Patients and methods: 600 women were included in the study and were planned to have elective caesarean section. 300 received dexamethasone 12 mg twice, 12 hours apart 48 hours before delivery. 300 patients were the control group.
The outcomes were: incidence of admission to neonatal intensive care unit (NICU), incidence of transient tachypnea of newborn (TTN), the incidence of respiratory distress syndrome (RDS) and the need for mechanical ventilation.
Dexamethasone which is a long acting corticosteroid can be used prior to elective cesarean section to decrease neonatal respiratory morbidity by enhacing fetal lung maturity.
39 studies on the registry are indexed under Tachypnea; 4 are open to participants now.
This study's enrollment of 600 is above the median of 100 across 30 interventional studies indexed under Tachypnea.
Browse Tachypnea studies →Ain Shams Maternity Hospital is the lead sponsor of 135 studies on the registry; 7 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Dexamethasone, im , 12 mg twice, 12 hrs apart, 48 hrs before elective cesarean section
Drug: Dexamethasone
Long acting corticosteroid
Also known as: Decadron
Special care baby unit
Special care baby unit admission for babies with respiratory distress
Time frame: 24 hours
Severity of respiratory distress
Severity of respiratory distress and the level of care in response
Time frame: 24 hours
This study is completed, as verified in Jan 2013. You cannot join it, but the record below documents what was studied.
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Ain Shams Maternity Hospital