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CompletedNCT01696916Updated Apr 15, 2014

Development of the Partial Pressure of Carbon Dioxide During Exercise and at Night in Patients With Chronic Obstructive Pulmonary Disease (COPD) IV

An interventional study of 6-minute walking test in Chronic Obstructive Pulmonary Disease, sponsored by Schön Klinik Berchtesgadener Land. Completed at 1 site in Germany. Open to participants aged 30 Years to 75 Years. Per ClinicalTrials.gov, last updated 2014-04-15.

Sponsored by Schön Klinik Berchtesgadener Land · Not applicable, Interventional, and Basic science

Phase
Not applicable
Study type
Interventional
Enrollment
75
Allocation
Not applicable
Ages
30 Years to 75 Years
Sex
All
01

Study summary

The aim of this study is to investigate the development of partial pressure of carbon dioxide during the 6-min walking test and during night in Chronic Obstructive Pulmonary Disease (COPD)-patients (GOLD stage IV). Therefore the partial pressure of carbon dioxide, oxygen saturation and the heart rate are registered by a device called "Sentec" during the mentioned periods. In addition a measurement of activity is realised by an activity monitor ("Sensewear").

02

Conditions studied

  • Chronic Obstructive Pulmonary Disease

Keywords

  • COPD
  • carbon dioxide
  • 6-minute walking test
03

In context

Lung Diseases

3,303 studies on the registry are indexed under Lung Diseases; 355 are open to participants now.

This study's enrollment of 75 is close to the median of 72 across 2,118 interventional studies indexed under Lung Diseases.

Browse Lung Diseases studies →

Lead sponsor

Schön Klinik Berchtesgadener Land is the lead sponsor of 51 studies on the registry; 2 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
30 Years to 75 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • COPD IV with and without a respiratory insufficiency
  • maximal paCO² of 55mmHg at admission (taken at rest by blood gas analysis without LTOT)

Exclusion criteria

Exclusion Criteria:

  • paCO² > 55mmHg
  • non-invasive ventilation
  • acute exacerbation
05

Study design

Phase
Not applicable
Primary purpose
Basic science
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
75 participants (actual)

Study arms

  • Experimental
    exercise testing

    6-minute walking test with pCO2 and pO2 measurement

    Procedure: 6-minute walking test

Interventions

  • Procedure6-minute walking test

    submaximum exercise test

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What researchers measure

Primary outcomes

  1. Increase of PaCO2 more than 5mmHg

    Time frame: From time of starting 6-minute walking test until the time of PaCO2-increase of more than 5mmHg assessed up to 6 minutes.

Secondary outcomes

  1. Change of PaCO2

    Time frame: From the beginning of the 6-minute walking test until peak PaCO2, assessed up to 6 minutes

07

Study locations

1 site
  • Klinikum Berchtesgadener Land
    Berchtesgaden, Germany
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Apr 15, 2014, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT01696916
Lead sponsor
Schön Klinik Berchtesgadener Land
Responsible party
Klaus Kenn (Head physician (department of pneumology), Schön Klinik Berchtesgadener Land) — Principal investigator
First posted
Oct 2, 2012
Start date
Mar 2012
Primary completion
Feb 2014
Completion
Feb 2014
Last update
Apr 15, 2014

Study contacts

Klaus Kenn, Dr. med.
study chair · Klinikum Berchtesgadener Land, Schön Klinik

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Apr 2014. You cannot join it, but the record below documents what was studied.

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