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Status unknownNCT01565603VALLOT 2011Updated Mar 30, 2012

Sleep and Cerebral Responses to High Altitude

An observational study in Acute Mountain Sickness, High Altitude Pulmonary Edema and High Altitude Cerebral Edema, sponsored by University Hospital, Grenoble. Status unknown. Open to male participants aged 18 Years to 50 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2012-03-30.

Sponsored by University Hospital, Grenoble · Observational

The sponsor has not verified this record recently (last verified Mar 2012), so the status shown — last known as Active, not recruiting — may be out of date.
Study type
Observational
Model
Case-only
Time perspective
Cross-sectional
Enrollment
12
Ages
18 Years to 50 Years
Sex
Male
01

Study summary

Mechanisms underlying high-altitude intolerance as well as exercise performance limitation in hypoxia still remain to be fully understood. Recent data suggest that sleep disturbances on one hand and cerebral perturbations on teh other hand may be key mechanisms. The investigators evaluated 12 healthy subjects at sea level and at 4400 m of altitude for 7 days in order to better describe sleep and cerebral responses. The investigators hypothesized that sleep and cerebral disturbances play a critical role for the developement of acute mountain sickness and for exercise performance limitation during acute high-altitude exposure.

02

Conditions studied

  • Acute Mountain Sickness
  • High Altitude Pulmonary Edema
  • High Altitude Cerebral Edema

Keywords

  • Hypoxia
  • Exercise
  • Sleep
  • Brain
  • Neuromuscular function
  • Heart
03

In context

Altitude Sickness

189 studies on the registry are indexed under Altitude Sickness; 44 are open to participants now.

This study's enrollment of 12 is below the median of 94 across 30 observational studies indexed under Altitude Sickness.

Browse Altitude Sickness studies →

Lead sponsor

University Hospital, Grenoble is the lead sponsor of 815 studies on the registry; 205 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 50 Years
Sexes eligible
Male
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

Healthy young subjects

Inclusion criteria

  • 18 to 50 yrs old
  • Male

Exclusion criteria

Exclusion Criteria:

  • Respiratory, cardiac, metabolic or neuromuscular diseases
  • History of severe acute mountain sickness
05

Study design

Observational model
Case-only
Time perspective
Cross-sectional
Enrollment
12 participants (actual)
Biospecimen retention
Samples without dna
06

Study locations

No study locations are listed for this record.

07

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 30, 2012, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
08

Registry details

Key details

Study ID
NCT01565603
Lead sponsor
University Hospital, Grenoble
Responsible party
AdministrateurDRC (Principal investigator, University Hospital, Grenoble) — Principal investigator
First posted
Mar 28, 2012
Start date
Jul 2011
Primary completion
Oct 2011
Completion
Oct 2012 (estimated)
Last update
Mar 30, 2012

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Mar 2012. You cannot join it, but the record below documents what was studied.

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