An interventional study of Carbon dioxide Laser ablation and Electrocoagulation in Condylomata Acuminata, sponsored by Ruhr University of Bochum. Completed at 1 site in Germany. Open to female participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-09-15.
Sponsored by Ruhr University of Bochum · Not applicable, Interventional, and Treatment
In a randomized clinical trial of 114 women undergoing Treatment for condyloma acuminata, two surgical methods, the carbon dioxide laser Ablation and the excision by electrocoagulation, will be compared. The primary outcome of the study is the cosmetic result judged by the Patient 6 weeks after Treatment using a 11-step numerical rating scale (NRS), secondary outcomes are intervention time, operative complications, subjects and users satisfaction, postoperative pain and recurrence of genital warts.
Exclusion Criteria:
Excision of genital warts using a carbon dioxide laser, ie CO2 Laser
Device: Carbon dioxide Laser ablation
Excision of genital warts using a superficial electrical coagulation mode, ie spray coagulation
Device: Electrocoagulation
surgical Instrument to achieve excision of genital warts by a pulsed laser of 15 Watt voltage - NOTE: pulsed 15 W was never used; the actual setting was 5W continuous
surgical Instrument to achieve excision of genital warts by a deep tissue electrocoagulation of 80 Watt voltage
Cosmetic result
Cosmetic result judged by the Patient 6 weeks after Treatment using a 11-step numerical rating scale (NRS)
Time frame: 6 weeks
users satisfaction
surgeons will score their satisfaction concerning the used technique by using a 11-step numerical rating scale (NRS) within 30 minutes after surgery
Time frame: 30 minutes
Operation time
the time from the beginning of the Treatment until the end of the operation (the end of hemostatic interventions) will be measured in minutes
Time frame: 20 minutes
Postoperative pain
patients will score their postoperative pain Level using a 11-step numerical rating scale (NRS) within 5 hours after surgery
Time frame: 5 hours
Subjects satisfaction
Patients will score their Overall satisfaction by using a 11-step numerical rating scale (NRS) 6 weeks after Treatment
Time frame: 6 weeks
Recurrence of genital warts
an examination will be performed 12 weeks after surgery; Recurrence of genital warts will be determined if one or more Areas are infected by genital warts
Time frame: 12 weeks
Operative complications
Operative complications defined as necessity to intervene surgically up to 14 days postoperatively (number of patients with operative complications and type of complication)
Time frame: 14 days
Subjects satisfaction
Patients will score their Overall satisfaction by using a 11-step numerical rating scale (NRS) 12 weeks after Treatment
Time frame: 12 weeks
Cosmetic result
Cosmetic result judged by the Patient 12 weeks after Treatment using a 11-step numerical rating scale (NRS)
Time frame: 12 weeks
Plan to share: Yes — The datasets generated and analyzed during the current study are not publicly available due to patient confidentiality and institutional data-protection policies, but they can be made available from the corresponding author on reasonable request. Requests will be evaluated to ensure that proposed use complies with ethical approvals and data-use agreements.
No publications or documents are linked to this record.
This study is completed, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.
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Ruhr University of Bochum