A Phase 4 interventional study of Control group and Intervention group in Coronary Artery Disease, sponsored by Deutsches Herzzentrum Muenchen. Status unknown at 1 site in Germany. Open to participants aged 18 Years to 95 Years. Per ClinicalTrials.gov, last updated 2011-10-18.
Sponsored by Deutsches Herzzentrum Muenchen · Phase 4, Interventional, and Diagnostic
The objective of this study is to compare a standard coronary CT angiography scan protocol with conventional image reconstruction with a scan protocol using reduced tube current and a new image reconstruction algorithm. The investigators hypothesize that the image quality of the new scan protocol is not inferior, while radiation dose estimates are reduced by around 30%.
Secondary endpoints of the study include quantitative image quality parameters, prevalence of non-diagnostic studies, prevalence of coronary artery plaques and plaque characteristics (calcified, non-calcified, mixed) and prevalence of follow-up examinations.
5,598 studies on the registry are indexed under Coronary Artery Disease; 957 are open to participants now.
This study's planned enrollment of 400 is above the median of 124 across 3,436 interventional studies indexed under Coronary Artery Disease.
Browse Coronary Artery Disease studies →Deutsches Herzzentrum Muenchen is the lead sponsor of 112 studies on the registry; 10 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Conventional coronary CT angiography using standard reconstruction technique (filtered back projection).
Radiation: Control group
Using the new scan protocol with 30 % less tube current and iterative image reconstruction algorithm.
Radiation: Intervention group
Conventional coronary CT angiography using standard reconstruction technique (filtered back projection).
Using the new scan protocol with 30 % less tube current and iterative image reconstruction algorithm.
Image quality
Compared with a conventional scan protocol the use of a new scan protocol using iterative image reconstruction and reduced tube current is associated with a comparable diagnostic image quality, while the radiation dose estimates are significantly reduced.
Time frame: 1 month
Quantitative image quality parameters
Quantitative image quality parameters, e.g. image noise, signal and contrast intensity, signal- and contrast-to-noise-ratios
Time frame: 1 month
Prevalence of non-diagnostic examinations
Prevalence of non-diagnostic examinations in both study arms.
Time frame: 1 month
Prevalence of coronary artery plaques
Prevalence of coronary artery plaques and coronary artery plaques characteristics (non-calcified, calcified, mixed) in both study arms.
Time frame: 1 month
Prevalence of follow-up examinations
Prevalence of follow-up examinations in both study arms.
Time frame: 1 month
Radiation dose
Radiation dose in both study arms.
Time frame: 1 month
This study is status unknown, as verified in Oct 2011. You cannot join it, but the record below documents what was studied.
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Deutsches Herzzentrum Muenchen