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CompletedNCT01412476Updated Mar 26, 2012

Coenzyme Q10 and Vitamin A, C, E in Relation to the Oxidative Stress, Antioxidant Enzyme Activity and Inflammation in Subjects With Metabolic Syndrome

An observational study in Metabolic Syndrome, sponsored by Chung Shan Medical University. Completed at 1 site in Taiwan. Open to participants aged 20 Years to 80 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2012-03-26.

Sponsored by Chung Shan Medical University · Observational

Study type
Observational
Model
Case-control
Time perspective
Cross-sectional
Enrollment
72
Ages
20 Years to 80 Years
Sex
All
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Study summary

Metabolic syndrome (MS) is a significant risk factor of cardiovascular disease. However, the relationships between coenzyme Q10, antioxidant vitamins (Vitamin A, C, E) and the prevention of the risk of MS are still inconsistent. The purposes of this study are going to investigate the relation of coenzyme Q10, antioxidant vitamins concentration with the blood lipid levels, the markers of lipid peroxidation (TBARS), antioxidant enzymes activities (catalase, glutathione peroxidase and superoxide dismutase), and the inflammatory markers (hs-CRP,IL-6 and adiponectin). The investigators will recruit MS patients (case group, n = 100) and age-gender matched healthy subjects from previous study(n = 105) as a control group . The inclusion criteria of MS are according to the Bureau of Health Promotion, Department of Health in Taiwan (2007).Hopefully, the results of this study could provide the information to what has been know in MS subjects. The investigators expect coenzyme Q10 or antioxidant vitamins could be a preventive supplement to reduce the risk of MS.

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Conditions studied

  • Metabolic Syndrome
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In context

Metabolic Syndrome

1,964 studies on the registry are indexed under Metabolic Syndrome; 329 are open to participants now.

This study's enrollment of 72 is below the median of 200 across 458 observational studies indexed under Metabolic Syndrome.

Browse Metabolic Syndrome studies →

Lead sponsor

Chung Shan Medical University is the lead sponsor of 124 studies on the registry; 26 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
20 Years to 80 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Probability sample

Study population

The investigators recruited MS patients (case group, n = 100). The inclusion criteria of MS are according to the Bureau of Health Promotion, Department of Health in Taiwan (2007). The health subject were recrited from previous study (n = 105).

Inclusion criteria

  • Metabolic syndrome
  • Healthy individuals with normal blood biochemical values.

Exclusion criteria

Exclusion Criteria:

  • Age \< 18y
  • Antioxidant vitamins supplements use
  • Pregnant women
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Study design

Observational model
Case-control
Time perspective
Cross-sectional
Enrollment
72 participants (actual)
Biospecimen retention
Samples without dna

Groups and cohorts

  • case group

    Subjects with metabolic syndrome

  • control group

    Healthy individuals

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Study locations

1 site
  • Ping-Ting Lin
    Taichung, Taiwan
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 26, 2012, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT01412476
Lead sponsor
Chung Shan Medical University
Collaborators
National Science Council, Taiwan
First posted
Aug 9, 2011
Start date
Aug 2010
Completion
Mar 2012
Last update
Mar 26, 2012

Study contacts

Ping-Ting Lin, Ph.D.
principal investigator · Chung Shan Medical University

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Mar 2012. You cannot join it, but the record below documents what was studied.

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