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RecruitingNCT06003686Updated Sep 30, 2026

Spinal Cord Injury Model Systems (SCIMS) - Education Module

An interventional study of PVA Consumer Guide and WebMD in Spinal Cord Injuries, Obesity and Cardiometabolic Syndrome, sponsored by University of Miami. Recruiting at 3 sites in United States. Open to participants aged 18 Years to 70 Years. Per ClinicalTrials.gov, last updated 2026-09-30.

Sponsored by University of Miami · Not applicable, Interventional, and Prevention

Phase
Not applicable
Study type
Interventional
Enrollment
250
Allocation
Randomized
Ages
18 Years to 70 Years
Sex
All
01

Study summary

The purpose of this study is to find out if receiving education regarding increased risks of cardiometabolic disease helps subjects understand these risks and how these risks participants' health.

02

Conditions studied

  • Spinal Cord Injuries
  • Obesity
  • Cardiometabolic Syndrome
03

Who can participate

Ages eligible
18 Years to 70 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  1. Men and Women with SCI/D aged 18-70 years.
  2. Neurologically complete and incomplete American Spinal Injury Association (ASIA) Impairment scale (AIS) A-D spinal cord levels C5 and below.
  3. Enrolled no later than 4 months following discharge from initial rehabilitation from SCI.

Exclusion criteria

Exclusion Criteria:

  1. Pregnancy determined by urine testing in sexually active females.
  2. Cognitive impairment that compromises the legitimacy of consent.
  3. Grade 3-4 pressure injury at the time of study entry.
  4. Prisoners
04

Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
250 participants (estimated)

Study arms

  • Experimental
    Paralyzed Veterans of America (PVA) Cardio-Metabolic Disease (CMD) Consumer Guide Group

    Hard paper copy of as well as an electronic copy of the guide will be provided to subjects and study staff will provide a general review of the contents of the guide with subjects during their education sessions. Participants will be in this group for 6 months.

    Behavioral: PVA Consumer Guide

  • Active comparator
    WebMD Group

    Subjects will be introduced to WebMD and its contents. A brief document will be provided that includes site summary and website. Study staff will provide a very brief overview of the site. Participants will be in this group for 6 months.

    Behavioral: WebMD

Interventions

  • BehavioralPVA Consumer Guide

    Subject's will receive education on the PVA consumer guide 3 times over the course of the study. Each session will be approximately 10-15 minutes and will consist of a general review of the nutrition, exercise, and general healthy living guidelines content included.

  • BehavioralWebMD

    Subject's will receive education on how to navigate the WebMD site and find information on health, exercise and nutrition 3 times over the course of the study. Each session will be approximately 10-15 minutes and will consist of a general review of the health and wellness content available on the website. At study completion, subjects in this group will be provided with the PVA guide and a brief orientation of the nutrition, exercise, and general healthy living guidelines content included in the guide.

05

What researchers measure

Primary outcomes

  1. Change in Effectiveness of education modules as determined in the Knowledge Test

    Effectiveness as determined by the number of correct answers on the Knowledge Test where the higher number of correct answers indicates increased knowledge of the information provided.

    Time frame: baseline, up to 6 months

Secondary outcomes

  1. Change in Body Weight as determined by kilograms (kg)

    Body weight will be measured in kilograms

    Time frame: baseline, up to 6 months

  2. Change in Body composition as determined by Dual X-ray Absorptiometry (DXA)

    Body composition will be measured in grams using DXA

    Time frame: baseline, up to 6 months

  3. Change in Body composition as determined by Dual X-ray Absorptiometry (DXA) in Percentage

    Body composition will be expressed as a percentage of body fat (BF) using DXA

    Time frame: baseline, up to 6 months

  4. Change in sugar metabolism as determined by Insulin resistance (IR)

    Sugar metabolism will be determined as IR calculated using the formula (fasting serum glucose\*fasting serum insulin/22.5). Lower values indicate a higher degree of insulin sensitivity. Fasting values are obtained from blood samples

    Time frame: baseline, up to 6 months

  5. Change in Quality of Life (QoL) as measured by Quality Index Spinal Cord Injury Version III

    A composite score will be obtained to assess change in QoL using a six-point Likert scale. Scores for satisfaction section range from "1- very satisfied" to "6-very dissatisfied". On the important section scoring ranges from "1-very important" to "6- very unimportant"

    Time frame: baseline, up to 6 months

  6. Change in Quality of Life (QoL) Using the International Spinal Cord Injury Basic Data Set

    QoL values will be determined using a scale ranging from 0 (completely dissatisfied) to 10 (completely satisfied).

    Time frame: baseline, up to 6 months

  7. Change in heart disease risk as determined by cholesterol

    Risk of heart disease will be measured from a blood sample in mg/dL

    Time frame: baseline, up to 6 months.

  8. Change in heart disease risk as determined by blood pressure (BP)

    BP will be measured in mmHg using an arm cuff

    Time frame: baseline, up to 6 months.

06

Study locations

1 of 3 sites recruiting
  • MedStar National Rehabilitation Network
    Washington D.C., District of Columbia 20010, United States
    Active, not recruiting
  • University of Miami - Miami Project to Cure Paralysis
    Miami, Florida 33136, United States
    Active, not recruiting
  • Baylor Scott & White Institute for Research
    Dallas, Texas 75246, United States
    Recruiting
07

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

08

Registry details

Key details

Study ID
NCT06003686
Lead sponsor
University of Miami
Collaborators
National Institute on Disability, Independent Living, and Rehabilitation Research
Responsible party
Gary Farkas (Principal Investigator, University of Miami) — Principal investigator
First posted
Aug 22, 2023
Start date
Mar 5, 2024
Primary completion
Dec 31, 2026 (estimated)
Completion
Dec 31, 2026 (estimated)
Last update
Sep 30, 2026

Study contacts

Patricia Graham, MS
Contact
pgraham1@med.miami.edu
3052435119
Gary Farkas, PhD
principal investigator · University of Miami

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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