An observational study in Asthma, sponsored by University of South Florida. Completed at 1 site in United States. Open to participants aged 18 Years to 60 Years. Per ClinicalTrials.gov, last updated 2012-06-28.
Sponsored by University of South Florida · Observational
Myeloid-derived suppressor cells (MDSC) have been studied for their ability to suppress T cell responses in vivo and in vitro. As a result, MDSC can regulate cellular responses to chronic inflammatory conditions such as cancer, leading to the induction of tolerance and, ultimately, tumor escape from immune surveillance.
3,439 studies on the registry are indexed under Inflammation; 629 are open to participants now.
This study's enrollment of 20 is below the median of 95 across 895 observational studies indexed under Inflammation.
Browse Inflammation studies →University of South Florida is the lead sponsor of 333 studies on the registry; 63 are open to participants now.
Of its 17 completed or terminated interventional studies of FDA-regulated products, 4 (24%) have results posted.
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Ages eligible for study: 18 to 60 years Genders eligible for study: male and female Signed and dated written informed consent is obtained prior to study blood draw.
Subjects being actively treated for chronic moderate to severe asthma based on National Heart Lung and Blood Institute guidelines (figure 1). Subjects must carry the diagnosis of asthma (made by a physician) for a minimum of six months.
Subjects within the first seven days of an acute asthma exacerbation, as determined by the referring physician.Able to give informed consent.
Exclusion Criteria:
Patients experiencing acute exacerbation of their asthma
Two groups are being enrolled. The first group is chronic asthma patients with FEV1 below 80% and FEV1/FVC ratio reduced by 5%
To identify and characterize specific cell types (human dendritic cells, myeloid-derived suppressor cells and T lymphocytes) that are present in acute and chronic asthma.
Time frame: one year from start of study
This study is completed, as verified in Oct 2010. You cannot join it, but the record below documents what was studied.
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University of South Florida