A Phase 1 interventional study of Rumination Focused CBT in Depression and Anxiety Disorders, sponsored by VU University of Amsterdam. Completed at 1 site in Netherlands. Open to participants aged 15 Years to 22 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2014-12-03.
Sponsored by VU University of Amsterdam · Phase 1, Interventional, and Prevention
Depression and anxiety disorders are highly prevalent and associated with reduced quality of life for patients and enormous economic costs for society. Although effective treatments are available, a substantial number of patients fail to respond, and the time between disorder onset and treatment is typically long. The development of prevention programs therefore appears promising. The current project aims to prevent depression and anxiety by targeting excessive levels of worry and rumination, two important risk factors for emotional disorders. Participants will be selected on the basis of a high score on two validated questionnaires on worry and rumination. They will be randomly assigned to a rumination-focused cognitive-behavioral training delivered in a group format, a rumination-focused cognitive-behavioral training delivered via internet, or a no-training control condition. It is expected that both versions of the rumination-focused training will reduce symptoms of depression and anxiety, will reduce the incidence of major depressive episodes and generalized anxiety disorder, and will reduce symptom levels of other emotional disorders.
see above
8,057 studies on the registry are indexed under Depression; 1,641 are open to participants now.
This study's enrollment of 251 is above the median of 84 across 6,720 interventional studies indexed under Depression.
Browse Depression studies →VU University of Amsterdam is the lead sponsor of 47 studies on the registry; 7 are open to participants now.
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RFCBT-group. This group training is based on research showing that dysfunctional forms of rumination are characterized by an abstract evaluative style of processing, whereas functional forms of of processing are more concrete and process-focused. The training uses psycho-education, functional analysis, group discussion, experiential exercises and behavioral experiments to facilitate the shift from dysfunctional ruminative thinking to a more helpful concrete thinking style.
Behavioral: Rumination Focused CBT
The online training is based on research showing that dysfunctional forms of rumination are characterized by an abstract evaluative style of processing, whereas functional forms of of processing are more concrete and process-focused. The training uses psycho-education, functional analysis, experiential exercises and behavioral experiments to facilitate the shift from dysfunctional ruminative thinking to a more helpful concrete thinking style.
Behavioral: Rumination Focused CBT
No training control group. Participants within this condition received no treatment, but only filled out the outcome measures at each measurement period.
see arms
Also known as: RFCBT
Beck Depression Inventory II (BDI-II)
self-report questionnaire of depressive symptom severity
Time frame: 1 year after training has ended
Mood and Anxiety Symptom Questionnaire (MASQ-30)
Symptom severity of anxiety
Time frame: 1 year after training has ended
This study is completed, as verified in Dec 2014. You cannot join it, but the record below documents what was studied.
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VU University of Amsterdam