A Phase 3 interventional study of Conventional resistance training program and Whole body vibration resistance training program in COPD, sponsored by University Hospital, Ghent. Completed at 1 site in Belgium. Open to participants aged 40 Years to 80 Years. Per ClinicalTrials.gov, last updated 2011-12-12.
Sponsored by University Hospital, Ghent · Phase 3, Interventional, and Treatment
Pulmonary rehabilitation has been emerged as a recommended standard of care for patients with chronic lung disease based on a growing body of scientific evidence. A set of evidence-based guidelines were published in American College of Chest Physicians (ACCP) and the American Association of Cardiovascular and Pulmonary Rehabilitation (AACVPR). Since then, the published literature in pulmonary rehabilitation has increased substantially, and other societies have published important statements about pulmonary rehabilitation (eg, the American Thoracic Society and the European Respiratory Society).
In patients with COPD, there is a strong scientific basis for implementing conventional resistance training (CRT) in addition to endurance training. Endurance training, such as walking, is a key component of pulmonary rehabilitation and improves in exercise tolerance and muscular endurance. However, this type of training may not reverse muscle weakness or atrophy. For that reason, strength training seems to be the optimum training modality to increase muscle mass and strength.
Recently, Whole-Body-Vibration (WBV) training has been promoted as an alternative for resistance training on multigym equipment. In WBV training, the subject stands on a platform that generates vertical sinusoidal vibration, during which static and dynamic exercises can be performed.
The present study is conducted to provide an answer on the following question: will a resistance training program, such as the whole body vibration, be even effective than a conventional resistance training program in patients with COPD.
3,303 studies on the registry are indexed under Lung Diseases; 355 are open to participants now.
This study's enrollment of 62 is below the median of 72 across 2,118 interventional studies indexed under Lung Diseases.
Browse Lung Diseases studies →University Hospital, Ghent is the lead sponsor of 665 studies on the registry; 156 are open to participants now.
Of its 5 completed or terminated interventional studies of FDA-regulated products, 4 (80%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Behavioral: Conventional resistance training program
Behavioral: Whole body vibration resistance training program
Conventional resistance training program is followed.
WBV training on FITVIBE
estimation of the change of 6 MWD before and after 12 weeks resistance training program (CRT versus WBV training)
estimation of the change of 6 MWD (submaximal walking test)after a 12 week conventional resistance training program or after a 12 week whole body vibration training program
Time frame: before and after 12 weeks
changes in muscle strength (quadriceps force)after CRT or after WBV training in patients with COPD
measured by modified Microfet before and after 12 weeks of training.
Time frame: before and after 12 weeks
changes in body composition after CRT or after WBV training in patients with COPD
measured by bioelectrical impedance analysis: Fat Free Mass (FFM)before and after 12 weeks of training.
Time frame: before and after 12 weeks
changes in maximal exercise capacity after CRT or after WBV training in patients with COPD
measured by cyclo-ergospirometry before and after 12 weeks of training
Time frame: before and after 12 weeks
changes in muscle force after CRT or after WBV training in patients with COPD
measured by handgrip force, maximal inspiratory pressure (PImax) and maximal expiratory pressure (PEmax)before and after 12 weeks of training
Time frame: before and after 12 weeks
changes in Quality of life after CRT or after WBV training in patients with COPD
measured by CRDQ (Chronic Respiratory Disease Questionnaire)before and after 12 weeks of training
Time frame: beforer and after 12 weeks
changes in Dyspnea scores after CRT or after WBV training in patients with COPD
measured by Chronic Respiratory Disease Questionnaire domain dyspnea (CRDQd) and by the BORG scale before and after 12 weeks of training.
Time frame: before and after 12 weeks
changes in 6MWD and the endurance test on the bicycle after CRT or after WBV training in patients with COPD
measured by endurance test on the bicycle (75% Max. Workload)before and after 12 weeks of training. This test will also be repeated after 6 weeks of training.
Time frame: before and after 12 weeks
This study is completed, as verified in Dec 2011. You cannot join it, but the record below documents what was studied.
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University Hospital, Ghent