An interventional study of Walking on an instrumented treadmill and Walking on an instrumented treadmill while dual-tasking in Gait, sponsored by University Hospital, Ghent. Recruiting at 1 site in Belgium. Open to participants aged 6 Years to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-09-21.
Sponsored by University Hospital, Ghent · Not applicable, Interventional, and Basic science
The aim of this study is to collect a large set of norm/control data on an instrumented treadmill (the Gait Real-time Analysis Interactive Lab - GRAIL) at the university hospital of Ghent for the purpose of clinical studies as well as for clinical interpretation.
We hypothesize that this norm/control data will provide reference data of the normal gait patterns in the healthy population such that we can then use it to identify gait abnormalities in populations with pathology.
The following data will be collected on the GRAIL while subjects walk at different gait speeds: 3D kinematics, kinetics, and EMG.
Additionally, 3D kinematics, kinetics, and EMG data will be collected when performing either a cognitive (Stroop Color and Word Test) or motor (requiring arm swing) dual-task while walking at comfortable walking speed.
University Hospital, Ghent is the lead sponsor of 689 studies on the registry; 160 are open to participants now.
Of its 5 completed or terminated interventional studies of FDA-regulated products, 4 (80%) have results posted.
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- Healthy participants
Exclusion Criteria:
Participants will be asked to walk at different gait velocities for 1 minute. The treadmill speed will be increased incrementally at 0.1m/s intervals until just before running.
Other: Walking on an instrumented treadmill · Other: Walking on an instrumented treadmill while dual-tasking
Participants will be asked to walk at different gait velocities for 1 minute. The treadmill speed will be increased incrementally at 0.1m/s intervals until just before running.
Participants aged between 6 and 17 years will be asked to walk at comfortable walking speed while playing either a cognitive (Stroop Color and Word Test) or motor (requiring arm swing) game.
Kinematics
3D kinematics of lower and upper limb joints while walking (degrees)
Time frame: single point assessment in 1 day
Kinetics
3D kinetics of lower limb joints while walking (Nm)
Time frame: single point assessment in 1 day
EMG
Muscle activity of 32 lower and upper limb muscles (micorvolts)
Time frame: single point assessment in 1 day
EMG synergies
Synergy analysis will be carried using the EMG data (variance accounted for -VAF)
Time frame: single point assessment in 1 day
Spatiotemporal parameters
Spatial parameters (m)
Time frame: single point assessment in 1 day
Spatiotemporal parameters
Temporal parameters (s)
Time frame: single point assessment in 1 day
Spatiotemporal parameters
Walking velocity (m/s)
Time frame: single point assessment in 1 day
Gait deviation index
Based on kinematics, the lower-limb gait deviations will be calculated (degrees)
Time frame: single point assessment in 1 day
Game result (cognitive task)
Score (% correct)
Time frame: single point assessment in 1 day
Game result (motor task)
Score (% correct)
Time frame: single point assessment in 1 day
Demographic data
Gender, age
Time frame: single point assessment in 1 day
height (cm)
anthropometric data
Time frame: single point assessment in 1 day
weight
anthropometric data
Time frame: single point assessment in 1 day
segment lengths (cm)
anthropometric data
Time frame: single point assessment in 1 day
M-ABC-2
Standardized tool to indentify motor functioning in children
Time frame: single point assessment in 1 day
Developmental Coordination Disorder Questionnaire (DCDQ)
Brief parent questionnaire to screen for coordination disorders in children
Time frame: single point assessment in 1 day
Plan to share: No
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