An interventional study of Argon laser trabeculoplasty and Selective laser trabeculoplasty in Glaucoma, sponsored by Sunnybrook Health Sciences Centre. Completed at 1 site in Canada. Open to participants aged 18 Years to 60 Years. Per ClinicalTrials.gov, last updated 2013-10-10.
Sponsored by Sunnybrook Health Sciences Centre · Not applicable, Interventional, and Treatment
Laser trabeculoplasty is a routine treatment for glaucoma and can be performed with either argon (ALT) or selective Yag (SLT) lasers. The effectiveness of each has not been studied in patients under 60 years, which is younger than average for the procedure. The study hypothesis is that there will be no difference between the two laser types.
Forty-two young patients (age 29 to 60) had one eye randomized to ALT (n = 22) or SLT (n = 20). Intraocular pressure was measured prior to laser and 1 hour, 1 day, 6 weeks, 3 months, every 3 months until 2 years, and then yearly post-laser. χ2 analysis and student's t-test were used to determine statistical significance.
1,818 studies on the registry are indexed under Glaucoma; 231 are open to participants now.
This study's enrollment of 42 is below the median of 65 across 1,272 interventional studies indexed under Glaucoma.
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Of its 6 completed or terminated interventional studies of FDA-regulated products, 2 (33%) have results posted.
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Exclusion Criteria:
Patients received standard argon laser treatment
Procedure: Argon laser trabeculoplasty
Patients received a standard selective laser treatment
Procedure: Selective laser trabeculoplasty
Argon laser 600-800 mW, 0.1seconds, 50 micron spot size, 45 - 55 burns over 180 degrees of trabecular meshwork
Also known as: ALT
Selective laser trabeculoplasty 0.7 - 0.8 mJ, 400 micron spot size, 3 nanosecond, 45 - 55 burns over 180 degrees of trabecular meshwork.
Also known as: SLT
Intraocular pressure
The intraocular pressure was measured at 6 weeks, 4.5 months, 9, 12, 18 and 24 months following the laser treatment.
Time frame: Two years
This study is completed, as verified in Oct 2013. You cannot join it, but the record below documents what was studied.
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Sunnybrook Health Sciences Centre