An observational study in Thymoma, sponsored by Istituto Clinico Humanitas. Completed at 1 site in Italy. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2009-08-28.
Sponsored by Istituto Clinico Humanitas · Observational
This is a retrospective analysis of biological characteristics of thymoma and thymic carcinoma patients.
The aim of the present study is to investigated the genetic alterations in tumor samples of a series of all WHO-defined subtypes of thymoma patients using high resolution microarray- comparative genomic hybridization (CGH) followed by hierarchical cluster analyses of the data to identify specific patterns of genetic aberrations and genes associated with each subtype. Moreover, tumor samples will be also investigated for some specific potential therapy targets by immunoistichemistry, mutation analysis, and fluorescence in situ hybridization (FISH) analysis. All these biological data will be correlated with clinical patients characteristics and survival data.
126 studies on the registry are indexed under Thymoma; 36 are open to participants now.
This study's enrollment of 134 is above the median of 71 across 20 observational studies indexed under Thymoma.
Browse Thymoma studies →Istituto Clinico Humanitas is the lead sponsor of 275 studies on the registry; 71 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Thymoma and thymic carcinoma patients will be retrospectively analyzed. Patients will be selected based on the availability of tumor tissue.
Exclusion Criteria:
Primary objective: to evaluate the presence of genetic alterations and specific potential therapy targets.
Time frame: one year
Secondary objective: to correlate the biological characteristics with clinical characteristics and survival data of patients.
Time frame: one year
This study is completed, as verified in Aug 2009. You cannot join it, but the record below documents what was studied.
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Istituto Clinico Humanitas