An interventional study of PET/CT in Myocardial Infarction, Coronary Artery Disease and Cardiac Catheterization, sponsored by Washington University School of Medicine. Terminated at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2018-08-29.
Sponsored by Washington University School of Medicine · Not applicable, Interventional, and Diagnostic
This study is being done to determine if a picture taking test of the heart, positron emission tomography/computed tomography (or cardiac PET/CT), can identify the blockages in the heart arteries that lead to heart attacks when compared to the standard of heart catheterization.
Heart catheterization, in which a thin plastic tube, or catheter, is placed into an artery in the arm or leg and advanced into the heart arteries, is the procedure that you and your doctor have decided to pursue to look for heart artery blockages. It is being performed as part of your standard care and not for research purposes. The research procedure (cardiac PET/CT), which will be performed at a later date is a combination of heart CT (a test that involves the use of x-rays to identify heart artery blockages) and heart PET (an imaging test that uses a radioactive drug to look at how the heart uses fuel (sugar and fats) These tests will be combined (PET/CT) to look for the presence and type of blockage in your heart arteries.
It is important to develop a test that can determine if and what type of blockage you have in your heart arteries as the presence and type of heart artery blockage is a very important predictor of heart attack and death from heart attack.
5,598 studies on the registry are indexed under Coronary Artery Disease; 957 are open to participants now.
This study's enrollment of 3 is below the median of 124 across 3,436 interventional studies indexed under Coronary Artery Disease.
Browse Coronary Artery Disease studies →Washington University School of Medicine is the lead sponsor of 1,765 studies on the registry; 271 are open to participants now.
Of its 324 completed or terminated interventional studies of FDA-regulated products, 212 (65%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Patient will have a PET/CT imaging study to determine cardiac stenosis, F-18 FDG and heparin/intralipid infusion and Contrast Dye.will be administered.
Diagnostic Test: PET/CT
Patient will have one imaging modality - a Positron Emitting Tomography CT which includes F-18 FDG and heparin/intralipid infusion and Contrast Dye.
Also known as: PET/positron Emission Tomography imaging
Number of Participants With Clear Anatomical Landmarks Confirmed by CT
Coronary FDG uptake will be measured at the site of coronary stenosis. The target coronary stenosis will be identified by its proximity to a clear anatomical landmark seen on CT and conventional angiography.
Time frame: During PET CT scan, an average of 2 hours
| Milestone | Positron Emitting Image, F-18 FDG, Contrast Dye |
|---|---|
| Started | 3 |
| Completed | 3 |
| Not completed | 0 |
Coronary FDG uptake will be measured at the site of coronary stenosis. The target coronary stenosis will be identified by its proximity to a clear anatomical landmark seen on CT and conventional angiography.
| Participants | Positron Emitting Image |
|---|---|
| Number of Participants With Clear Anatomical Landmarks Confirmed by CT | 3 |
Collected over During PET CT scan an average of 2 hours. Non-serious events are listed at a 0% frequency threshold.
| Group | Deaths | Serious | Other |
|---|---|---|---|
| Positron Emitting Image, F18 FDG, Contrast Dye | 0/3 (0%) | 0/3 (0%) | 0/3 (0%) |
| Age, Categorical(Participants) | Positron Emitting Image, F18 FDG, Contrast Dye |
|---|---|
| <=18 years | 0 |
| Between 18 and 65 years | 3 |
| >=65 years | 0 |
| Sex: Female, Male(Participants) | Positron Emitting Image, F18 FDG, Contrast Dye |
|---|---|
| Female | 2 |
| Male | 1 |
| Race and Ethnicity Not Collected(Participants) | Positron Emitting Image, F18 FDG, Contrast Dye |
|---|
| Region of Enrollment(Participants) | Positron Emitting Image, F18 FDG, Contrast Dye |
|---|---|
| United States | 3 |
Plan to share: No — there is no plan to make individual participant data available to other researchers
No publications or documents are linked to this record.
This study is terminated, as verified in Aug 2018. You cannot join it, but the record below documents what was studied.
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Washington University School of Medicine