An observational study in Primary Open Angle Glaucoma, sponsored by Wills Eye. Completed at 1 site in United States. Open to participants aged 40 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2016-11-21.
Sponsored by Wills Eye · Observational
Glaucoma is a group of diseases in which visual loss occurs because of damage to the optic nerve. Research has shown that certain genes may cause glaucoma in some cases. So far, research has only been able to find the genes responsible for glaucoma in a small percentage of people who have glaucoma. The purpose of this project is to study the genes in patients with and without glaucoma to find additional genes that may be responsible for causing glaucoma.
Four tubes of blood will be taken from 100 people. Of those, half will have primary open angle glaucoma (POAG) and the other half will be controls (normals), half will be caucasians and the other half will be african americans, half male and half female. All groups will have a routine ophthalmic eye exam, color vision, snellen vision, and visual field done.
1,818 studies on the registry are indexed under Glaucoma; 231 are open to participants now.
This study's enrollment of 97 is close to the median of 103 across 454 observational studies indexed under Glaucoma.
Browse Glaucoma studies →Wills Eye is the lead sponsor of 74 studies on the registry; 3 are open to participants now.
Of its 12 completed or terminated interventional studies of FDA-regulated products, 10 (83%) have results posted.
Counted across the registry records on this site, refreshed daily.
glaucoma clinic
Exclusion Criteria:
Primary Open Angle Glaucoma (POAG)
Controls (Normals, patients without glaucoma)
The investigators will quantify the spectrum of changes in mitochondrial respiration, relative mitochondrial DNA content, and oxidative stress associated with different types of glaucoma.
Time frame: one blood draw
Plan to share: Yes — Two manuscripts have been written and published.
This study is completed, as verified in Nov 2016. You cannot join it, but the record below documents what was studied.
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