An observational study in Nevus, Pigmented, sponsored by Medical University of Graz. Completed at 1 site in Austria. Open to participants aged Up to 18 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2008-01-25.
Sponsored by Medical University of Graz · Observational
Changes in nevus count in 16 children (8m, 8f) aged between 2 and 17 years (median:8 years) suffering from different malignancies were examined every three months during a one-year period after starting chemotherapy. An age and sex matched control group underwent the same skin examinations.At the start of our study, the range of number of nevi in the chemotherapy group was 0-133, in the control group 2-199.
Objectives:
Patients given chemotherapy because of different malignancies have an increased susceptibility to cutaneous tumours and infection and a change of number of nevi during treatment is discussed. We investigated wether total nevi count changes in children undergoing chemotherapy. Therefore 16 (8m, 8f) children suffering from leukaemia (11), lymphoma (2), adenosarcoma of the kidney (1), Ewing´s sarcoma (1) and neuroblastoma (1) aged between 2 and 17 years (median:8 years), under chemotherapy at the pediatric department of oncology, were examined at the beginning and 9-12 months after starting chemotherapy. As control group age and sex matched children of the local population were used.
Materials and Methods:
At the beginning of chemotherapy the nevi were counted on the total body. All nevi were larger in diameter than 1mm and as melanocytic lesion identifiable. Clinical and dermoscopic photographs were taken of every nevus. If the patient had more than 50 nevi, only nevi on the face, right arm, upper back and the buttocks were documented. Reassessment was repeated every 3 month.
Conclusion:
In our patients under chemotherapy during one year the development of new nevi is similar to sex and age matched children of the general population. During this short period development of nevi seems not to be influenced by chemotherapy.
19 studies on the registry are indexed under Nevus, Pigmented; 6 are open to participants now.
This study's enrollment of 32 is below the median of 50 across 11 observational studies indexed under Nevus, Pigmented.
Browse Nevus, Pigmented studies →Medical University of Graz is the lead sponsor of 471 studies on the registry; 98 are open to participants now.
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Study group: children suffering from malignancies requiring chemotherapy were recruited consecutively at the department of pediatric oncology
Control group: children were recruited consecutively at our department for pigmented skin lesions at the department of dermatology
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Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Malignancy means cancer. Criteria about another or earlier malignancy ask whether you have had a different cancer, usually within a set number of years.
Some are commonly allowed, such as treated skin cancers other than melanoma and early cancers removed completely — check the exceptions this study lists.
Cancer (malignancy)
Malignancy means cancer. Criteria about another or earlier malignancy ask whether you have had a different cancer, usually within a set number of years.
Some are commonly allowed, such as treated skin cancers other than melanoma and early cancers removed completely — check the exceptions this study lists.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Study group: 16 children under 18 years undergoing systemic chemotherapy
Control group: 16 age and sex matched healthy children under 18 years
total body nevus count
Time frame: Every three months during a one year period
The record gives a start of Feb 2006, a primary completion of Dec 2007 and a completion of Dec 2007. It does not say whether these dates are actual or estimated.
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This study is completed, as verified in Jan 2008. You cannot join it, but the record below documents what was studied.
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