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CompletedNCT00581022Updated Aug 10, 2018

Objective Sleep Disturbances in Orthostatic Intolerance

An observational study in Postural Tachycardia Syndrome and Chronic Orthostatic Intolerance, sponsored by Satish R. Raj. Completed at 1 site in United States. Open to participants aged 18 Years to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2018-08-10.

Sponsored by Satish R. Raj · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
100
Ages
18 Years to 65 Years
Sex
All
01

Study summary

We wish to study sleep architecture in patients with chronic orthostatic intolerance. We will test the null hypothesis that there is no difference in time during the various phases of sleep between patients and healthy control subjects.

02

Conditions studied

  • Postural Tachycardia Syndrome
  • Chronic Orthostatic Intolerance

Keywords

  • postural tachycardia syndrome
  • sleep
  • insomnia
03

In context

Dyssomnias

324 studies on the registry are indexed under Dyssomnias; 51 are open to participants now.

This study's planned enrollment of 100 is below the median of 126 across 63 observational studies indexed under Dyssomnias.

Browse Dyssomnias studies →

Lead sponsor

Satish R. Raj is the lead sponsor of 7 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 65 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

patients diagnosed with chronic orthostatic intolerance by the Vanderbilt Autonomic Dysfunction Center

Inclusion criteria

  • diagnosed with chronic orthostatic intolerance (or healthy subject)

Exclusion criteria

Exclusion Criteria:

  • overt cause or acute orthostatic intolerance
  • pregnancy or lactation
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
100 participants (estimated)

Groups and cohorts

  • 1

    Patients with Chronic Orthostatic Intolerance

    Procedure: Polysomnography

Interventions

  • ProcedurePolysomnography

    Overnight Sleep Study

    Also known as: Sleep Study

06

What researchers measure

Primary outcomes

  1. Duration of sleep

    Time frame: 1 night

Secondary outcomes

  1. Time in individual phases of sleep

    Time frame: 1 night

  2. sleep latency

    Time frame: 1 might

07

Study locations

1 site
  • Vanderbilt Unviersity
    Nashville, Tennessee 37232, United States
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 10, 2018, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00581022
Lead sponsor
Satish R. Raj
Collaborators
National Center for Research Resources (NCRR)
Responsible party
Satish R. Raj (Assistant Professor of Medicine & Pharmacology, Vanderbilt University Medical Center) — Sponsor-investigator
First posted
Dec 27, 2007
Start date
Nov 2006
Primary completion
Dec 2016
Completion
Dec 2016
Last update
Aug 10, 2018

Study contacts

Satish R Raj, MD MSCI
principal investigator · Vanderbilt University

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Aug 2018. You cannot join it, but the record below documents what was studied.

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