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CompletedNCT00533650Updated Jul 29, 2016

Proof of Concept (Bone Resorption/Bone Mineral Density) Study (0429-005)

A Phase 2 interventional study of MK0429 in Post-Menopausal Osteoporosis, sponsored by Merck Sharp & Dohme LLC. Completed. Open to female participants aged 50 Years to 75 Years. Per ClinicalTrials.gov, last updated 2016-07-29.

Sponsored by Merck Sharp & Dohme LLC · Phase 2, Interventional, and Treatment

Phase
Phase 2
Study type
Interventional
Enrollment
227
Allocation
Randomized
Ages
50 Years to 75 Years
Sex
Female
01

Study summary

A study to asses the safety and efficacy of MK0429 in postmenopausal women with osteoporosis.

02

Conditions studied

  • Post-Menopausal Osteoporosis
03

In context

Osteoporosis

1,640 studies on the registry are indexed under Osteoporosis; 212 are open to participants now.

This study's enrollment of 227 is above the median of 95 across 1,133 interventional studies indexed under Osteoporosis.

Browse Osteoporosis studies →

Lead sponsor

Merck Sharp & Dohme LLC is the lead sponsor of 2,114 studies on the registry; 133 are open to participants now.

Of its 489 completed or terminated interventional studies of FDA-regulated products, 362 (74%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
50 Years to 75 Years
Sexes eligible
Female
Accepts healthy volunteers
No

Inclusion criteria

  • Person is a women with osteoporosis who is unwilling or unable to take other treatments for osteoporosis

Exclusion criteria

Exclusion Criteria:

  • Person has had a previous fracture
  • Person has rheumatoid arthritis. Person has has certain types of cancer
  • Person has donated blood or has been in another investigational study within the last 4 weeks
05

Study design

Phase
Phase 2
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double
Enrollment
227 participants (actual)

Interventions

  • DrugMK0429
06

Study locations

No study locations are listed for this record.

07

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 29, 2016, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
08

Registry details

Key details

Study ID
NCT00533650
Lead sponsor
Merck Sharp & Dohme LLC
Responsible party
Sponsor
First posted
Sep 21, 2007
Start date
Dec 2000
Primary completion
Oct 2002
Completion
Oct 2002
Last update
Jul 29, 2016

Study contacts

Medical Monitor
study director · Merck Sharp & Dohme LLC
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in May 2016. You cannot join it, but the record below documents what was studied.

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