A Phase 4 interventional study of CPAP and Non Invasive Ventilation in Pulmonary Edema, sponsored by Ospedale S. Giovanni Bosco. Completed at 1 site in Italy. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2007-04-03.
Sponsored by Ospedale S. Giovanni Bosco · Phase 4, Interventional, and Treatment
To assess the intubation rate in patients affected by severe cardiogenic pulmonary edema treated with CPAP or NPPV.
Background Although non-invasive ventilation has shown to be an effective treatment for acute cardiogenic pulmonary oedema (ACPO), literature still lacks of multi-centre randomised prospective studies that compares CPAP with NPPV.
Aim of the study was to assess efficacy and safety of CPAP and NPPV in patients with ACPO.
Methods 80 patients with ACPO were randomly assigned to receive CPAP or NPPV (40 for each group) through a face mask.
Inclusion criteria were: severe dyspnoea, respiratory rate > 30, PaO2/FiO2 \< 200, muscle fatigue.
Main end-points were endotracheal intubation, length of ventilation, hospital length of stay and mortality.
138 studies on the registry are indexed under Pulmonary Edema; 24 are open to participants now.
This study's enrollment of 80 is above the median of 68 across 72 interventional studies indexed under Pulmonary Edema.
Browse Pulmonary Edema studies →Ospedale S. Giovanni Bosco is the lead sponsor of 7 studies on the registry; none are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Intubation rate
time of recovery
hospital length of stay
mortality and improvement in gas exchange
This study is completed, as verified in Apr 2007. You cannot join it, but the record below documents what was studied.
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Ospedale S. Giovanni Bosco