An interventional study of Intravenous Infusion of Magnesium Sulfate in Rest Cramps, sponsored by University of British Columbia. Completed at 1 site in Canada. Open to participants aged 19 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2008-12-10.
Sponsored by University of British Columbia · Not applicable, Interventional, and Treatment
This study sets out to show whether infusions of magnesium can lessen the frequency of rest cramps and to determine whether rest cramp sufferers have a deficiency in magnesium.
Subjects will be randomized to receive 5 days of 4 hour IV infusions of D5W either with or without 20 mmol magnesium sulfate added. Twenty four hour urinary excretion of magnesium will be determined on the first day of infusions to assess whether magnesium deficiency is present. Ten normal controls will also undergo a single infusion and collection of urine to serve as a comparison group for the urinary excretion data.
95 studies on the registry are indexed under Muscle Cramp; 9 are open to participants now.
This study's planned enrollment of 54 is close to the median of 50 across 85 interventional studies indexed under Muscle Cramp.
Browse Muscle Cramp studies →University of British Columbia is the lead sponsor of 1,309 studies on the registry; 253 are open to participants now.
Of its 6 completed or terminated interventional studies of FDA-regulated products, 1 (17%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
See Detailed Description.
Change in the frequency of leg cramps per week (active versus placebo) over the first 30 days post infusions compared to the 30 days prior to randomization (as recorded in patient diaries).
Time frame: See above
Assessment of magnesium status at trial entry as determined by 24 hour fractional excretion of magnesium on day 1 of infusions.
Subjective assessment as to whether cramps were unchanged, more, or less frequent /painful/"bothersome" over the 3 months. following infusions.
Time frame: See above
Overall quality of life changes as measured by an SF36 questionnaire.
This study is completed, as verified in Dec 2008. You cannot join it, but the record below documents what was studied.
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University of British Columbia