A Phase 2 interventional study of darusentan in Hypertension, sponsored by Gilead Sciences. Completed. Open to participants aged 35 Years to 85 Years. Per ClinicalTrials.gov, last updated 2007-01-18.
Sponsored by Gilead Sciences · Phase 2, Interventional, and Treatment
This is a research study of a new experimental drug called darusentan. Darusentan is not currently approved by the U.S. Food and Drug Administration (FDA) for use in the United States, which means that a doctor cannot prescribe this drug. The purpose of this study is to determine if darusentan is effective in reducing systolic blood pressure in subjects with resistant systolic hypertension, despite treatment with full doses of three or more blood pressure lowering drugs, including a diuretic.
6,689 studies on the registry are indexed under Hypertension; 965 are open to participants now.
Browse Hypertension studies →Gilead Sciences is the lead sponsor of 680 studies on the registry; 24 are open to participants now.
Of its 259 completed or terminated interventional studies of FDA-regulated products, 249 (96%) have results posted.
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Exclusion Criteria:
Co-primary efficacy measures are changes in trough sitting systolic BP from baseline through Weeks 8 and 10.
Secondary efficacy measurements are change in trough sitting diastolic BP from baseline to study Week 10; change in mean 24-hour systolic BP, as measured by ABPM; and the percent of subjects who reached systolic BP goal after 10 weeks of treatment.
No study locations are listed for this record.
This study is completed, as verified in Aug 2006. You cannot join it, but the record below documents what was studied.
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Gilead Sciences