A Phase 4 interventional study of Rosuvastatin or atorvastatin or simvastatin and clopidogrel in Coronary Heart Disease, sponsored by AstraZeneca. Completed at 18 sites in Sweden. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2010-11-19.
Sponsored by AstraZeneca · Phase 4 and Interventional
The purpose of this study is to compare the efficacy between two lipid lowering treatments, rosuvastatin (10-40 mg) and atorvastatin (20-80 mg) in reducing low-density lipoprotein cholesterol (LDL-C) levels after 16 weeks of treatment in patients with coronary heart disease
3,639 studies on the registry are indexed under Heart Diseases; 461 are open to participants now.
This study's enrollment of 255 is above the median of 100 across 1,778 interventional studies indexed under Heart Diseases.
Browse Heart Diseases studies →AstraZeneca is the lead sponsor of 3,429 studies on the registry; 270 are open to participants now.
Of its 357 completed or terminated interventional studies of FDA-regulated products, 173 (48%) have results posted.
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Also known as: Crestor
Compare the efficacy of once daily treatment with rosuvastatin with the efficacy of treatment with atorvastatin
Compare the impact of treatment with rosuvastatin to that of atorvastatin and simvastatin on clopidogrel initiated inhibition of platelet aggregation in a subset of subjects recruited in the Stockholm region.
Compare the impact of treatment with rosuvastatin to that of atorvastatin on clopidogrel initiated inhibition of platelet aggregation in all subjects, totally and on each dose of rosuvastatin and atorvastatin.
Compare the efficacy of treatment with rosuvastatin with the efficacy of treatment with atorvastatin in reducing LDL-C levels
Compare the efficacy of once daily treatment with rosuvastatin with that of atorvastatin in modifying levels of TC, HDL-C, TG, nonHDL-C (TC-HDL-C), LDL-C
Compare the titration schedule of rosuvastatin with that of atorvastatin.
Determine the safety by evaluating the incidence and severity of adverse events and abnormal laboratory values through 16 weeks of treatment
This study is completed, as verified in Nov 2010. You cannot join it, but the record below documents what was studied.
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AstraZeneca