ClinicalTrials.gg
CompletedNCT00114907Updated Apr 6, 2007

Effects of Black Tea on Cardiovascular Disease in the Mauritian Population

An interventional study of Consumption of black tea in Cardiac Disease, sponsored by University of Mauritius. Completed at 1 site in Mauritius. Open to participants aged 25 Years to 70 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2007-04-06.

Sponsored by University of Mauritius · Not applicable, Interventional, and Prevention

Phase
Not applicable
Study type
Interventional
Enrollment
270
Allocation
Randomized
Ages
25 Years to 70 Years
Sex
All
01

Study summary

It is proposed to investigate the association between consumption of black tea and various selective fasting blood serum and urine biomarkers in a Mauritian population with ischaemic heart diseases. This study, the first of its kind, will provide clinical data on the potential prophylactic propensities of Mauritian black tea against cardiovascular disease, which remains one of the major health threats to the Mauritian population.

Read the detailed description

OBJECTIVES

Our broad objectives will be to:

  • Survey and recruit patients with ischaemic heart diseases in a randomized sample representative of the Mauritian population (ethnicity, gender, age, social and economical status) and record their medical history,
  • Collect fasting blood serum and urine at baseline and after supplement of control volume of tea infusion and water from study group and control group respectively,
  • Optimize techniques to determine levels of specific biomarkers from above body fluid samples,
  • Investigate existing correlation between tea consumption and risk of cardiovascular diseases in Mauritian population

Our specific objectives will be to:

  • Select a randomised group of the Mauritian population, with ischaemic heart disease, who has been referred to the Cardiac Centre, Pamplemousses for Angiography and a group of people showing no risk of cardiovascular diseases
  • Inform the people about the motives of the study and seek consent from those willing to participate in the study,
  • Evaluate the levels of biomarkers of oxidative stress (total cholesterol, LDL, HDL, triglycerides, homocysteine, atrial natriuretic peptides, brain natriuretic peptides, 8-hydroxydeoxyguanosine, isoprostanes, hydroxyeicosatetraenoic acid, products of protein damage, uric acid and glycosylated haemoglobin) from 8-10 hr fasting blood serum and urine at baseline from all participants
  • Supply the study group with a control volume of tea infusion and the control group with the same amount of water for a defined period of time followed by a two week wash out period with water.
  • Study biomarkers as above from 8-10 hr fasting blood serum and urine in two week intervals during the supplement regime
  • Investigate the existing correlation between tea consumption and levels of biomarkers of cardiovascular diseases in a Mauritian sample population.
02

Conditions studied

  • Cardiac Disease

Keywords

  • Tea
  • Oxidative stress markers
  • cardiovascular disease
  • polyphenolics
  • double blind
  • Ischaemic cardiac disease
03

In context

Heart Diseases

2,135 studies on the registry are indexed under Heart Diseases; 252 are open to participants now.

This study's enrollment of 270 is above the median of 129 across 931 interventional studies indexed under Heart Diseases.

Browse Heart Diseases studies →

Lead sponsor

University of Mauritius is the lead sponsor of 4 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
25 Years to 70 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • 25-70 years
  • Non smokers
  • >40%

Exclusion criteria

Exclusion Criteria:

  • Alcohol consumption > 4 standard drinks/day
  • women receiving hormone replacement therapy
Terms in these criteria, in plain language(2)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

LVEF (left ventricular ejection fraction)

The share of blood the heart’s main pumping chamber (the left ventricle) pushes out with each beat, measured by an echocardiogram (heart ultrasound) or a MUGA scan. About 50–70% is normal.

Postmenopausal

Periods have stopped for good: usually no period for 12 months in a row without another medical reason, sometimes confirmed by a blood test (FSH).

05

Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Randomized
Intervention model
Single group
Masking
Double
Enrollment
270 participants

Interventions

  • BehavioralConsumption of black tea
06

What researchers measure

Primary outcomes

  1. The study will assess the effect of tea consumption on the incidence of cardiovascular diseases

Secondary outcomes

  1. The effect of tea consumption will be evaluated on a number of markers of oxidative stress associated with cardiovascular disease

07

Study locations

1 site
  • University of Mauritius
    Reduit, Mauritius
08

Timeline

Tracking since Sep 25, 2026
Not marked actual or estimatedDates not marked actual or estimated

The record gives a start of Jun 2005 and a completion of Jun 2005. It does not say whether these dates are actual or estimated.

How these figures are worked out, and which studies are left out of them.

Registered
Jun 17, 2005
First posted
Jun 20, 2005
Start
Jun 2005
Completion
Jun 2005
Last update
Apr 6, 2007
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
No changes since tracking began. The registry record was last updated on Apr 6, 2007, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00114907
Lead sponsor
University of Mauritius
Collaborators
Mauritius Research Council, Cardiac Centre, Pamplemousses, London South Bank University
First posted
Jun 20, 2005
Start date
Jun 2005
Completion
Jun 2005
Last update
Apr 6, 2007

Study contacts

Theeshan Bahorun, PhD
principal investigator · University of Mauritius
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jun 2005. You cannot join it, but the record below documents what was studied.

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