An interventional study of Cognitive-behavioral prevention program and Usual care in Depression, sponsored by Vanderbilt University. Completed at 4 sites in United States. Open to participants aged 13 Years to 17 Years. Per ClinicalTrials.gov, last updated 2022-01-31.
Sponsored by Vanderbilt University · Not applicable, Interventional, and Prevention
This study examines the impact of a group cognitive behavioral program aimed at preventing depressive disorders and symptoms in adolescents at risk for developing depression.
Depression is a prevalent, chronic, and impairing condition that is often undetected and becomes more difficult to treat as chronicity increases. There is an increasing need to conduct large-scale depression prevention studies in adolescents. This study evaluates a cognitive-behavioral prevention (CBP) program to determine its effectiveness in preventing depressive disorders in at-risk adolescents. The study also will ascertain the costs this intervention to inform attempts at future dissemination of the program in "real world" settings.
Participants in this study are randomly assigned to receive either CBP for eight weekly and 6 monthly continuation sessions or usual care. Depressive symptoms and disorders, levels of functioning, and medical and mental health care utilization are assessed at baseline and again at 2, 8, 20, and 32 months after intake.
8,057 studies on the registry are indexed under Depression; 1,641 are open to participants now.
This study's enrollment of 316 is above the median of 84 across 6,720 interventional studies indexed under Depression.
Browse Depression studies →Vanderbilt University is the lead sponsor of 508 studies on the registry; 19 are open to participants now.
Of its 7 completed or terminated interventional studies of FDA-regulated products, 5 (71%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Participants receive a group cognitive-behavioral prevention program, which involved 8 weekly sessions and 6 monthly sessions of CBT skills such as cognitive restructuring, problem-solving, assertivenss, and behavioral activation. Participants in this arm also were able to seek the same kinds of nonstudy treatments as described in the usual care arm.
Behavioral: Cognitive-behavioral prevention program
Participants receive usual care, which involves any type of treatment (e.g., psychotherapy, counseling, pharmacotherapy).
Other: Usual care
Cognitive-behavioral prevention program includes 8 weekly and 6 monthly group sessions.
Participants receive usual care
Onset of a probable or definite depressive episodes (i.e., Depression Symptom Rating greater or equal to 4)
a score of 4 or greater is considered an onset
Time frame: Time to a score of 4 or higher between baseline and 9 months using survival analysis
Number of depression-free days
Using the depression symptom ratings (DSR) (1-6), each week is given a score of 1 to 6; depression-free days are those with ratings of 1 or 2 on the DSR.
Time frame: Measured continuously through Month 33
This study is completed, as verified in Jan 2022. You cannot join it, but the record below documents what was studied.
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Vanderbilt University