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CompletedNCT00043602Updated Sep 26, 2013

Clinician Managed Interpersonal Psychotherapy

An Early Phase 1 interventional study of Standard interpersonal psychotherapy (IPT) and Clinician managed interpersonal psychotherapy (CM-IPT) in Depression and Depression, Postpartum, sponsored by University of Iowa. Completed at 1 site in United States. Open to female participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2013-09-26.

Sponsored by University of Iowa · Early Phase 1, Interventional, and Treatment

Phase
Early Phase 1
Study type
Interventional
Enrollment
140
Allocation
Randomized
Ages
18 Years and older
Sex
Female
01

Study summary

This 12-week study will evaluate the effectiveness of Clinician-Managed Interpersonal Psychotherapy (CM-IPT) in treating postpartum depression and will compare CM-IPT to standard IPT.

Read the detailed description

CM-IPT is delivered in 12 sessions over the course of a year. Standard IPT is delivered in 12 sessions in the first 12 weeks after treatment assignment.

02

Conditions studied

  • Depression
  • Depression, Postpartum
03

In context

Depression, Postpartum

528 studies on the registry are indexed under Depression, Postpartum; 124 are open to participants now.

This study's enrollment of 140 is above the median of 105 across 425 interventional studies indexed under Depression, Postpartum.

Browse Depression, Postpartum studies →

Lead sponsor

University of Iowa is the lead sponsor of 276 studies on the registry; 35 are open to participants now.

Of its 44 completed or terminated interventional studies of FDA-regulated products, 39 (89%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
Female
Accepts healthy volunteers
Yes

Inclusion criteria

  • Women between 8 and 24 weeks postpartum
  • Meet DSM-IV criteria for Major Depression
  • Hamilton Rating Scale for Depression score of 12 or more

Exclusion criteria

Exclusion criteria:

  • Active substance abuse
  • Psychotic disorders
05

Study design

Phase
Early Phase 1
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
140 participants (actual)

Study arms

  • Experimental
    1

    Participants will receive clinician-managed interpersonal psychotherapy

    Behavioral: Clinician managed interpersonal psychotherapy (CM-IPT)

  • Active comparator
    2

    Participants will receive standard interpersonal psychotherapy

    Behavioral: Standard interpersonal psychotherapy (IPT)

Interventions

  • BehavioralStandard interpersonal psychotherapy (IPT)

    Participants will receive 12 sessions of IPT over 12 weeks.

  • BehavioralClinician managed interpersonal psychotherapy (CM-IPT)

    Participants will receive 12 sessions of CM-IPT over 1 year.

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What researchers measure

Primary outcomes

  1. Hamilton Rating Scale for Depression

    Time frame: Measured at Week 12

07

Study locations

1 site
  • University of Iowa
    Iowa City, Iowa 52242, United States
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 26, 2013, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00043602
Lead sponsor
University of Iowa
Collaborators
National Institute of Mental Health (NIMH)
First posted
Aug 13, 2002
Start date
Sep 2001
Primary completion
Dec 2007
Completion
Dec 2007
Last update
Sep 26, 2013

Study contacts

Scott P. Stuart, MD
principal investigator · University of Iowa

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Sep 2013. You cannot join it, but the record below documents what was studied.

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