Ottawa Hospital Research Institute: all 544 studies

Page 3 of 6. Open to participants first (97), then studies with results posted, then the rest; newest registration first within each.

• Early Changes in Pain, Disease Activity, and Ultrasound Evidence of Inflammatory Synovitis in Patients Receiving JAK-inhibitor vs. TNF-inhibitor Therapy for Active Rheumatoid Arthritis: A Feasibility Study.Status unknownNCT05153200Phase 4
• Feasibility and Initial Clinical Impressions of Predictive Monitoring Integrated With the RACE TeamCompletedNCT05108376Not applicable
• Ozurdex Monotherapy TrialWithdrawnNCT05101928Phase 4
• Evaluating 6-months of HER2-targeted Therapy in Patients With HER2 Positive Early-stage Breast Cancer That Achieve a Pathological Complete Response to Neoadjuvant Systemic TherapyActive, not recruitingNCT04928261Phase 4
• Venous Thrombosis Virtual Surveillance in COVID-19CompletedNCT04865913
• Cellular Immuno-Therapy for COVID-19 ARDS Randomized Clinical TrialCompletedNCT04865107Phase 2
• Single Patient Protocol for an NRG1 Fusion Positive Metastatic Pancreatic Cancer Patient Using SeribantumabCompletedNCT04790695Phase 2
• CSRS Implementation - A Pilot StudyActive, not recruitingNCT04790058
• A Randomized, Multicenter Pragmatic Trial Comparing Bone Pain From a Single Dose of Pegfilgrastim to 5 Doses of Daily Filgrastim in Breast Cancer Patients Receiving Neoadjuvant/Adjuvant ChemotherapyCompletedNCT04781959Phase 4
• INVINCIBLE TRIAL: Intratumoral INT230-6 in Breast CancerStatus unknownNCT04781725Phase 2
• PSilocybin for psYCHological and Existential Distress in PALliative Care (PSYCHED-PAL)Active, not recruitingNCT04754061Phase 1/2
• Peripheral Nerve Injections for CRPSActive, not recruitingNCT04744675Phase 2
• Comparing Adductor Canal Block and Adductor Canal Block-Local Infiltration Analgesia for Post-operative Pain ManagementStatus unknownNCT04721119Not applicable
• A Phase II Window of Opportunity Trial of PRMT5 Inhibitor, GSK3326595, in Early Stage Breast CancerCompletedNCT04676516Phase 2
• Photobiomodulation for the Prevention of Radiation Induced Oral MucositisActive, not recruitingNCT04671862Not applicable
• Donation Advisor Clinical Decision Support Tool StudyCompletedNCT04661787
• Motion Capture as a Tool for the Assessment of Laparoscopic PerformanceCompletedNCT04646304Not applicable
• Unravelling the Etiology of Shoulder OsteoarthritisActive, not recruitingNCT04634773Not applicable
• Defining Optimum Cup Orientation for Hip Replacements Taking Into Account the Individual's Anatomy and Movement PatternsStatus unknownNCT04633525Not applicable
• Comparing Continuation or De-escalation of Bone Modifying Agents (BMA) in Patients Treated for Over 2 Years for Bone Metastases From Either Breast or Castration-resistant Prostate CancerActive, not recruitingNCT04549207Phase 4
• One Versus Two Unit Transfusions in Oncology Patients - The OTTOP Trial: A Randomized Open-label Pragmatic Controlled TrialStatus unknownNCT04544540Not applicable
• Radiation and Durvalumab Immunotherapy As Neoadjuvant Treatment for MIBCStatus unknownNCT04543110Phase 2
• Crystalloid FLUID Choices for Resuscitation of Hospitalized PatientsCompletedNCT04512950Phase 4
• Hyperbaric Versus Normobaric Oxygen Therapy for COVID-19 PatientsStatus unknownNCT04500626Phase 2/3
• RAFF4 Trial: Vernakalant vs. Procainamide for Acute Atrial Fibrillation in the Emergency DepartmentCompletedNCT04485195Phase 4
• Propranolol as an Anxiolytic to Reduce the Use of Sedatives From Critically-ill Adults Receiving Mechanical VentilationCompletedNCT04467086Phase 3
• Isopropyl Alcohol Inhalation as Anti-emetic Therapy in the Emergency DepartmentWithdrawnNCT04464915Not applicable
• Cellular Immuno-Therapy for COVID-19 Acute Respiratory Distress SyndromeCompletedNCT04400032Phase 1/2
• Prophylaxis for Patients at Risk to Eliminate Post-operative Atrial FibrillationStatus unknownNCT04392921Not applicable
• The PREPARE for COVID TrialStatus unknownNCT04392115Not applicable
• Prehospital Analgesia in Adults Using Inhaled Methoxyflurane : A Feasibility StudyCompletedNCT04287803Phase 4
• Evaluation of Palliative Care for Patients With ALS and Their CaregiversCompletedNCT04257760Not applicable
• Regional Anesthesia in Total Hip and Knee ArthroplastyStatus unknownNCT04257682Phase 4
• Transcranial Magnetic Stimulation for Psychological Distress in Patients With Advanced IllnessCompletedNCT04257227Not applicable
• Cellular Therapy for Extreme Preterm Infants at Risk of Developing Bronchopulmonary DysplasiaActive, not recruitingNCT04255147Phase 1
• Assessing Feasibility of Thromboprophylaxis With Apixaban in JAK2-positive Myeloproliferative Neoplasm PatientsCompletedNCT04243122Phase 2
• The PREPARE Trial: Exercise Before Surgery to Improve Recovery in Older People With FrailtyActive, not recruitingNCT04221295Not applicable
• Recipients With Limited Bimodal Benefit: HA or CROSStatus unknownNCT04155138Not applicable
• How TKA Implants Affect Muscle Quality and Activity During Daily Living and Immunological ResponseStatus unknownNCT04105179Not applicable
• IBD Neoplasia Surveillance Pilot RCTCompletedNCT04067778Not applicable
• Implementation of a Multi-component, Supervised Exercise Program for Patients With Type 2 Diabetes Mellitus.Status unknownNCT04030364Not applicable
• Patient Education Using 3D Printed ModelStatus unknownNCT04009252Not applicable
• NEC Thermography Infrared Imaging StudyCompletedNCT03994341
• The MODE Trial: Planned Caesarean Section Versus Induction of Labour for Women With Class III ObesityStatus unknownNCT03985618Not applicable
• ICU BEREAVE: Feasibility of a Multi-component Bereavement Support Intervention to Prevent Severe Grief ReactionTerminatedNCT03985592Not applicable
• Pre-pectoral Versus Sub-pectoral Implant Placement in Immediate Breast ReconstructionStatus unknownNCT03959709Not applicable
• Efficacy of an Exercise Program for Patients With Femoro-acetabular ImpingementActive, not recruitingNCT03949127Not applicable
• Evaluating Optimal Timing of Endocrine Therapy and Radiation Therapy in Early-stage Breast Cancer (REaCT-RETT)CompletedNCT03948568Phase 4
• An Educational Program to Improve Cardiac Arrest Diagnostic Accuracy of Ambulance TelecommunicatorsActive, not recruitingNCT03894059
• Comparing the Efficacy of Local Anesthetics in Mohs SurgeryStatus unknownNCT03871478Not applicable
• Adverse Long-term Consequences of Sleep Disordered Breathing: The Ottawa Hospital (TOH) Sleep DatabaseActive, not recruitingNCT03834792
• Pillow Use During Total Hip ArthroplastyStatus unknownNCT03825029Not applicable
• Dietary Counseling or Potassium Supplement to Increase Potassium Intake in Patients With High Blood PressureCompletedNCT03809884Phase 3
• Dislocation PrecautionsStatus unknownNCT03806114Not applicable
• Ribavirin to Enhance Hepatitis B Virus Nucleotide Analog Antiviral ActivityStatus unknownNCT03759782Phase 3
• Recovernow: Tablet-Based Speech Therapy For Post-Stroke AphasiaTerminatedNCT03755063Not applicable
• RA Effect on Cell Surface Molecules in VivoWithdrawnNCT03753867Phase 1
• Comparing Short-term Outcomes After Direct Anterior and SuperPATH Hip Arthroplasty ApproachesStatus unknownNCT03746925Not applicable
• Mid-point Transverse Process to Pleura Block for Breast Cancer Surgery: A Randomized Controlled TrialStatus unknownNCT03713255Not applicable
• Efficacy of Lymphovenous Bypass in the Treatment of Extremity LymphedemaWithdrawnNCT03683095
• Nasal Packing Following Endoscopic Endonasal Pituitary ResectionCompletedNCT03677713Not applicable
• Safety, Tolerability, Patient Satisfaction and Cost of 16.5% Subcutaneous Immunoglobulin (Cutaquig®) TreatmentStatus unknownNCT03677557Phase 4
• Saline Versus Albumin Fluid for Extracorporeal Removal With Slow Low Efficiency Dialysis Feasibility StudyCompletedNCT03665311Phase 2
• Comparing a Single-Dose vs. Twice Yearly Zoledronate in Patients With Early Stage Breast Cancer (REaCT-ZOL)CompletedNCT03664687Phase 4
• Comparing No Mechanical Bowel Preparation With Oral Antibiotics Alone in Patients Undergoing Elective Colon SurgeryActive, not recruitingNCT03663504Phase 4
• Hypovolemic Phlebotomy to Reduce Blood Transfusions in Major Hepatic ResectionsActive, not recruitingNCT03651154Not applicable
• Decreasing Hospital Admissions From the ED for AAFFCompletedNCT03627143Not applicable
• The PROMPT Pilot StudyCompletedNCT03626064Not applicable
• Evaluation of a Pilot Shard-care Program for Patients With Chronic Pain in the Champlain-LHINStatus unknownNCT03531476Not applicable
• Efficacy of Preoperative Muscle Training on Postoperative Orthopaedic Surgery RecoveryCompletedNCT03483519Not applicable
• Unicompartmental Knee Arthroplasty (UKA) Versus Total Knee Arthroplasty (TKA) of Medial OsteoarthritisWithdrawnNCT03457051Not applicable
• Patient Navigation in Primary Care and Access to Resources in the CommunityCompletedNCT03451552Not applicable
• Structured Polypharmacy Management Before Elective Non-cardiac Surgery in Frail and Elderly PeopleWithdrawnNCT03445767Not applicable
• Impact of Unexpected Death in Simulation: Skill Retention, Stress and EmotionsCompletedNCT03441425Not applicable
• The Association of Sex With Guideline-based Perioperative Care in Hip Fracture SurgeryCompletedNCT03422497
• Antimicrobial and Clinical Efficacy of Cliradex® as Compared With I-Lid'n Lash® Hygiene in Treating BlepharitisStatus unknownNCT03422146Not applicable
• Human Blood Specimen Collection to Evaluate Immune Cell FunctionCompletedNCT03422120
• Does CMV Induced Changes in NK Lymphocyte Biology Influence the Effectiveness of Antibody Therapy Used to Treat B Cell Lymphoproliferative Diseases?Status unknownNCT03417414
• Rocket® Pleural Catheters: QOL, Feasibility and Satisfaction in Recurrent MPE PatientsStatus unknownNCT03403855Not applicable
• Bedside Ultrasound in Detection of Pneumothorax Post Transthoracic Lung BiopsyCompletedNCT03397290Not applicable
• Cellular Immunotherapy for Septic ShockStatus unknownNCT03369275Phase 2
• The Use of Laparoscopic Transversus Abdominis Plane Block in Gastric Bypass Surgery (LapTAP)CompletedNCT03367728Phase 4
• Comparing Tapering Low Dose Dexamethasone to Other Standard of Care Therapies for TAPS in Breast Cancer PatientsCompletedNCT03348696Phase 4
• An Innovative Trial Assessing Donor Sex on Recipient MortalityStatus unknownNCT03344887Phase 4
• COPD Care Model on Clinical and Patient-Reported OutcomesCompletedNCT03332394
• SAHaRA: A Randomized Controlled TrialCompletedNCT03309579Not applicable
• WAVe Study - Weight Adjusted Dalteparin for Patients Over 90 kg With Acute Cancer Associated Venous ThromboembolismTerminatedNCT03297359Phase 2
• Improving Decisions About CPRCompletedNCT03287895Not applicable
• Folic Acid Clinical Trial: Follow up of Children (FACT 4 Child)CompletedNCT03269110
• Blood Pressure Measurement: Should Technique Define Targets?CompletedNCT03267420Not applicable
• Examining Effects of Spinal Fusion on Outcomes Following Total Hip ReplacementStatus unknownNCT03240484
• Simulation-Based Stress Inoculation TrainingCompletedNCT03233750Not applicable
• The EMPOwER Study Evaluating Multiparameter Gene Testing as a Predictor of Short Term Endocrine Therapy Response in Hormone Receptor Positive Breast CancersStatus unknownNCT03211572Phase 2
• Coconut Oil: Managing Radiation-Induced XerostomiaStatus unknownNCT03176368Not applicable
• Assessing Dementia Risk in the Community: The Dementia Population Risk ToolCompletedNCT03155815
• Optimizing the Diagnosis of Heparin Induced ThrombocytopeniaStatus unknownNCT03148912Not applicable
• Undiagnosed COPD and Asthma Population Study (UCAP)CompletedNCT03148210Not applicable
• Project to Assess Feasibility of a Rapid Access Metastatic Bone Disease ProgramWithdrawnNCT03134404
• ARC -Access to Resources in the CommunityCompletedNCT03105635Not applicable
• NeuroCognitive Communicator: Safety StudyStatus unknownNCT03100110Not applicable

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