National Institutes of Health: Schizophrenia trials

The registry lists 57 Schizophrenia studies with National Institutes of Health as lead sponsor. 0 are open to participants now and 7 have results posted.

Phase 1 4Phase 2 9Phase 3 2Phase 4 8No phase 36(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• The Use of Metformin in the Treatment of Antipsychotic-Induced Weight Gain in Schizophrenia (The METS Study)CompletedNCT00816907Phase 4Results posted
• Comparison of Optimal Antipsychotic Treatments for Adults With SchizophreniaCompletedNCT00802100Phase 4Results posted
• The Effects of Atomoxetine on Cognition and Brain Function Based on Catechol-O-methyltransferase(COMT) GenotypeTerminatedNCT00548327Phase 2Results posted
• Diabetes in Neuropsychiatric DisordersCompletedNCT00446992Phase 1/2Results posted
• Comparison of Antipsychotics for Metabolic Problems in Schizophrenia or Schizoaffective DisorderCompletedNCT00423878Phase 4Results posted
• Clinical Trial of Tolcapone for Cognition in SchizophreniaTerminatedNCT00044083Phase 2Results posted
• Comparison of Clozapine vs Olanzapine in Childhood-Onset Psychotic DisordersCompletedNCT00001656Phase 4Results posted
• Procedures for Sample Acquisition and Distribution for The Human Brain Collection CoreTerminatedNCT03092687
• Daily Intranasal Oxytocin for Childhood-Onset SchizophreniaTerminatedNCT01712646Phase 1/2
• Brain Functions Underlying Visuospatial Attention Deficits in SchizophreniaCompletedNCT01399437
• Brain Circuits in Schizophrenia and SmokingCompletedNCT01369966
• Nicotinic Receptor Density in Smoking and Nonsmoking SchizophrenicsWithdrawnNCT01246128
• Effects of Antipsychotics on Eating and Food Craving in People With SchizophreniaCompletedNCT01222793
• Assessment of Cannabis Craving in Schizophrenia Using Virtual RealityCompletedNCT01212081
• Imaging Cannabinoid CB1 Receptors in SchizophreniaTerminatedNCT01063335
• fMRI Study of Nicotinic Effect on Neurophysiology of SchizophreniaCompletedNCT01046526
• Influence of Nicotine on Cognitive Function in Schizophrenic Patients With and Without Comorbid Drug DependenceCompletedNCT01037075
• Neuroimaging Studies of Neurophysiological Phenotypes in SchizophreniaCompletedNCT01036568
• Dopamine Function and Reward Processing In SchizophreniaCompletedNCT01035996
• Effects of Nicotine on Areas of Impaired and Preserved Functioning in SchizophreniaCompletedNCT01034085
• Risk Perception in Drug-Dependent Adults With and Without SchizophreniaCompletedNCT01031563
• Assessment of Craving in Nicotine-Dependent Patients With Schizophrenia Using Virtual RealityCompletedNCT01031433
• Internal Monitoring of Eye Movement in SchizophreniaTerminatedNCT01011101
• Functional Relevance of Dopamine Receptors in Healthy Controls and Patients With Schizophrenia: Characterization Through [11C]NNC-112 and [18F]Fallypride Positron Emission TomographyCompletedNCT00942981
• Feasibility of Providing Cognitive Remediation to People With Schizophrenia in a Clinical NetworkCompletedNCT00930150Phase 4
• Transcranial Direct Current Brain Stimulation to Treat Patients With Childhood-Onset SchizophreniaTerminatedNCT00757497Phase 1
• Safety and Effectiveness of Sustained Release Bupropion in Treating Individuals With Schizophrenia Who SmokeCompletedNCT00307203Phase 4
• Effect of Bupropion on Smoking Behavior in Smokers With SchizophreniaCompletedNCT00218231Phase 2
• Effects of Transdermal Nicotine on Smoking, Craving and Withdrawal in People With SchizophreniaCompletedNCT00218218Phase 2
• Usability of a Website for People With SchizophreniaWithdrawnNCT00177879Not applicable
• Nicotine and Cotinine Levels in Smokers With Schizophrenia and Schizoaffective Disorder - 2CompletedNCT00135772
• Treating Nicotine Dependence in Schizophrenic Individuals: Effectiveness of Bupropion - 1CompletedNCT00124683Phase 2
• Timing of Voluntary Movement in Patients With SchizophreniaCompletedNCT00080548
• Imaging of Brain Receptors in Healthy Volunteers and in Patients With SchizophreniaCompletedNCT00061789Phase 2
• Effects of Modafinil on Brain Function in Patients With SchizophreniaCompletedNCT00057707Phase 1
• Screening for Childhood-Onset Psychotic DisordersTerminatedNCT00049738
• Nicotine Patch for Nicotine Dependence in Individuals With Schizophrenia or Schizoaffective Disorder - 1TerminatedNCT00046813Phase 4
• PET Scanning in Parkinson s DiseaseCompletedNCT00024622
• CATIE- Schizophrenia TrialCompletedNCT00014001Phase 4
• Glucose Regulation During Risperidone and Olanzapine TreatmentStatus unknownNCT00006195Not applicable
• Glycine to Treat Psychotic Disorders in ChildrenCompletedNCT00005658Phase 2
• Magnetic Resonance Imaging (MRI) of Neuropsychiatric Patients and Healthy VolunteersCompletedNCT00004571
• Electrophysiology and Blood Flow in Patients With Schizophrenia and Their SiblingsCompletedNCT00001921
• Eye Blink Response in Healthy Volunteers and Adults With SchizophreniaCompletedNCT00001920
• I-123 Brain Studies of Serotonin Metabolism in Psychiatric Patients and Normal VolunteersCompletedNCT00001771
• Treatment of Childhood Onset Psychiatric Disorders With Intravenous Immunoglobulin (IVIg)CompletedNCT00001768Phase 3
• Genetic Aspects of Neurologic and Psychiatric DisordersCompletedNCT00001544
• Genetic Study of SchizophreniaCompletedNCT00001486
• Neuropsychiatric Evaluation of Healthy Volunteers and Adults With SchizophreniaCompletedNCT00001323
• Neuroimaging of Dopamine Metabolism in Normal and Psychiatric PatientsCompletedNCT00001320
• Brain Tissue Collection for Neuropathological StudiesTerminatedNCT00001260
• Studies of Frontal Lobe Brain Functioning in SchizophreniaCompletedNCT00001258
• Inpatient Evaluation of Adults With SchizophreniaCompletedNCT00001247
• Brain Imaging of Childhood Onset Psychiatric Disorders, Endocrine Disorders and Healthy VolunteersCompletedNCT00001246
• Evaluating Genetic Risk Factors for Childhood-Onset SchizophreniaTerminatedNCT00001198
• Neuropsychological Evaluation of Psychiatric and Neurological PatientsCompletedNCT00001192
• Self-Management Therapy for Youth With SchizophreniaCompletedNCT00000387Phase 3