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CompletedNCT00001192Updated Jul 2, 2017

Neuropsychological Evaluation of Psychiatric and Neurological Patients

An observational study in Anxiety Disorder, Head Injury and Mood Disorder, sponsored by National Institute of Mental Health (NIMH). Completed at 7 sites in 3 countries. Open to participants aged Up to 95 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2017-07-02.

Sponsored by National Institute of Mental Health (NIMH) · Observational

Study type
Observational
Enrollment
4,300
Ages
Up to 95 Years
Sex
All
01

Study summary

This study will allow researchers to use various types of tests to evaluate cognitive and sensory functions. These tests, referred to as "batteries" will evaluate attention, executive functions, general intellectual functioning, language, memory, motor functions, orientation, personality, selected sensory and perceptual functions, vigilance (alertness), and visual-spatial functions. Children and adult patient will receive different test batteries.

The goals of this research study are to;

  1. Create descriptions based on the performance of each patient on the test batteries. Then use this information to relate patient behavior to their neurophysiological, neuroradiological, and biochemical descriptions.
  2. Define subgroups of patients based on their neurobehavior in order to decrease the variability of psychiatric diagnoses, treatments, and prognoses.
Read the detailed description

Neuropsychological tests are used to provide an assessment of cognitive functions in patients with idiopathic generalized epileptic (IGE) disorders and their first-degree relatives. The battery comprises tests designed to tap attention, memory, selected sensory and perceptual functions, vigilance, and visual-spatial functions. Modified batteries have been developed for the assessment of children ages 5-8, and children ages 8-16. The data provided by these batteries are compared with genetic profiles of the same participants that have been ascertained from blood samples analyzed by colleagues at the Mount Sinai School of Medicine/Columbia University in New York City.

02

Conditions studied

  • Anxiety Disorder
  • Head Injury
  • Mood Disorder
  • Schizophrenia
  • Seizures

Keywords

  • Executive Functions
  • Language
  • Attention
  • Visual-Spatial Ability
  • Memory
  • Motor Behavior
  • Intelligence
  • Personality
  • Visual and Auditory Functioning
  • Hand and Eye Dominance
  • Normal Volunteer
  • Neuropsychiatric Disorders
03

In context

Seizures

881 studies on the registry are indexed under Seizures; 143 are open to participants now.

This study's enrollment of 4,300 is above the median of 150 across 235 observational studies indexed under Seizures.

Browse Seizures studies →

Lead sponsor

National Institute of Mental Health (NIMH) is the lead sponsor of 359 studies on the registry; 46 are open to participants now.

Of its 25 completed or terminated interventional studies of FDA-regulated products, 24 (96%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
Up to 95 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

Patients.

Normal volunteers.

Exclusion criteria

EXCLUSION CRITERIA:

Subjects over 95 years of age.

Subjects with a history of alcohol or drug abuse, psychopathology, or central nervous system pathology, other than that which defines group membership, may be excluded.

05

Study design

Enrollment
4,300 participants
06

Study locations

7 sites
  • Childrens National Medical Center
    Washington, D.C., District of Columbia, United States
  • National Institutes of Health Clinical Center, 9000 Rockville Pike
    Bethesda, Maryland 20892, United States
  • Henry Ford Health Systems
    Detroit, Michigan 48202, United States
  • Mt. Sinai Medical Center
    New York, New York 10029-0574, United States
  • Columbia University
    New York, New York 10032-3784, United States
  • Genethon
    Every Cedex, France
  • Mosco Research Institute of Psychiatry
    Moscow, Russian Federation
07

References and documents

Publications

  • Johnstone EC, Owens DG, Bydder GM, Colter N, Crow TJ, Frith CD. The spectrum of structural brain changes in schizophrenia: age of onset as a predictor of cognitive and clinical impairments and their cerebral correlates. Psychol Med. 1989 Feb;19(1):91-103. doi: 10.1017/s0033291700011053. PubMed 2727213 ↗
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 2, 2017, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00001192
Lead sponsor
National Institute of Mental Health (NIMH)
First posted
Nov 4, 1999
Start date
Oct 18, 1983
Completion
Dec 20, 2006
Last update
Jul 2, 2017
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Dec 2006. You cannot join it, but the record below documents what was studied.

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