National Institute of Allergy and Infectious Diseases (NIAID): all 2,445 studies

Page 4 of 25. Open to participants first (182), then studies with results posted, then the rest; newest registration first within each.

• Mepolizumab in Episodic Angioedema With EosinophiliaTerminatedNCT04128371Phase 2Results posted
• Safety and Pharmacokinetics of RezafunginTerminatedNCT04117607Phase 1Results posted
• Treg Modulation With CD28 and IL-6 Receptor AntagonistsCompletedNCT04066114Phase 1/2Results posted
• Safety and Pharmacokinetic Study of Tenofovir Alafenamide (TAF)/Elvitegravir (EVG) Administered RectallyCompletedNCT04047420Phase 1Results posted
• H1N1v Virus Challenge Study in Healthy SubjectsCompletedNCT04044352Phase 1Results posted
• Ebola Sudan Chimpanzee Adenovirus Vector Vaccine in Healthy AdultsCompletedNCT04041570Phase 1Results posted
• Systems Analyses of the Immune Response to the Seasonal Influenza VaccineCompletedNCT04025580Phase 2Results posted
• Dosage-Escalation Study of the Safety and Immunogenicity of a Novel Rabies Vaccine ChAd155-RG vs. the Comparator RABAVERT Vaccine in Healthy Adult SubjectsCompletedNCT04019444Phase 1Results posted
• Evaluating the Safety and Immunogenicity of AGS-v PLUS, a Universal Mosquito-Borne Disease and Mosquito Control VaccineCompletedNCT04009824Phase 1Results posted
• Safety, Immunogenicity, and Protective Efficacy of Radiation Attenuated Plasmodium Falciparum NF54 Sporozoites (PfSPZ Vaccine) During Malaria Transmission Season in Healthy African Adult Women of Childbearing Potential in MaliCompletedNCT03989102Phase 2Results posted
• A Trial to Evaluate the Pharmacokinetics and Safety of AVYCAZ(R) in Combination With AztreonamCompletedNCT03978091Phase 1/2Results posted
• Randomized, Open Label Safety Trial of Dapivirine Vaginal Ring and Oral TRUVADA® Use in PregnancyCompletedNCT03965923Phase 3Results posted
• Sanaria PfSPZ Challenge With Pyrimethamine or Chloroquine Chemoprophylaxis Vaccination (PfSPZ-CVac Approach): A Randomized Double Blind Placebo Controlled Phase I/II Trial to Determine Safety and Protective Efficacy Against Natural Plasmodium Falcipa...CompletedNCT03952650Phase 1/2Results posted
• Flublok or Fluzone With Advax-CpG55.2 or AF03CompletedNCT03945825Phase 1Results posted
• Evaluating the Safety and Immunogenicity of an HIV-1 gp41 MPER-656 Liposome Vaccine in Healthy, HIV-uninfected Adult ParticipantsCompletedNCT03934541Phase 1Results posted
• Suppression Of Bacterial Vaginosis (BV) [SUBVert]CompletedNCT03930745Phase 2Results posted
• Evaluating the Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of Combinations of Monoclonal Antibodies PGT121, PGDM1400, 10-1074, and VRC07-523LS Administered Via Intravenous Infusion in Healthy, HIV-uninfected Adult ParticipantsCompletedNCT03928821Phase 1Results posted
• Pfs230D1M-EPA/AS01 Vaccine, a Transmission Blocking Vaccine Against Plasmodium Falciparum, in an Age De-Escalation Trial of Children and a Family Compound Trial in MaliCompletedNCT03917654Phase 2Results posted
• Safety and Immunogenicity of a Single Dose of the Recombinant Live-Attenuated Respiratory Syncytial Virus (RSV) Vaccines RSV ΔNS2/Δ1313/I1314L, RSV 6120/ΔNS2/1030s, RSV 276 or Placebo, Delivered as Nose Drops to RSV-Seronegative Children 6 to 24 Months of AgeTerminatedNCT03916185Phase 1/2Results posted
• Intravenous Fosfomycin Pharmacokinetics StudyCompletedNCT03910673Phase 1Results posted
• Dried Blood Spot Testing of CMV Detection in HCT RecipientsCompletedNCT03910478Not applicableResults posted
• Single-Dose Study to Evaluate the PKs of Pretomanid in Participants With Renal Impairment Compared to Participants With Normal Renal FunctionCompletedNCT03896750Phase 1Results posted
• A Clinical Trial of the Safety, Pharmacokinetics and Hematologic Effects of Imatinib on Myelopoiesis in Adults When Given With and Without Isoniazid and RifabutinCompletedNCT03891901Phase 2Results posted
• StAT-TB (Statin Adjunctive Therapy for TB): A Phase 2b Dose-finding Study of Pravastatin in Adults With TuberculosisCompletedNCT03882177Phase 2Results posted
• Omalizumab as Monotherapy and as Adjunct Therapy to Multi-Allergen OIT in Food Allergic ParticipantsCompletedNCT03881696Phase 3Results posted
• VRC 313: A Trivalent Virus-like Particle (VLP) Encephalitis Vaccine (WEVEE) in Healthy AdultsCompletedNCT03879603Phase 1Results posted
• A Clinical Trial in Healthy, HIV-1-Uninfected Adult Participants to Compare the Safety, Tolerability and Immunogenicity of CH505TF gp120 Produced From Stably Transfected Cells to CH505TF gp120 Produced From Transiently Transfected CellsCompletedNCT03856996Phase 1Results posted
• Clinical Study of a Diagnostic Device for NG, TV and CT in WomenCompletedNCT03852316Not applicableResults posted
• Experimental Human Infection With Neisseria GonorrhoeaeCompletedNCT03840811Phase 1Results posted
• Combination Therapy With VRC01 and 10-1074 in HIV-Infected Individuals Undergoing Sequential Treatment InterruptionsTerminatedNCT03831945Phase 1Results posted
• Safety Study of Hepatitis E Vaccine (HEV239)CompletedNCT03827395Phase 1Results posted
• Immunogenicity and Safety Study of Inactivated Subunit H5N1 Influenza Vaccine in Prior Recipients of Live Attenuated H2N2, H6N1 and H9N2 Influenza Vaccines and in H5N1 and Live Attenuated Vaccine Naïve IndividualsCompletedNCT03816878Phase 1Results posted
• Dose, Safety, Tolerability and Immunogenicity of an Influenza H1 Stabilized Stem Ferritin Vaccine in Healthy AdultsCompletedNCT03814720Phase 1Results posted
• Safety and Immunotherapeutic Activity of an Anti-PD-1 Antibody (Cemiplimab) in Participants With HIV-1 on Suppressive cARTTerminatedNCT03787095Phase 1/2Results posted
• Dose, Safety, Tolerability, and Immunogenicity of an HIV-1 Vaccine, VRC-HIVRGP096-00-VP, With Alum in Healthy AdultsCompletedNCT03783130Phase 1Results posted
• Safety and Efficacy of Subcutaneous Sarilumab in Improving the Quality of Life in People With Indolent Systemic MastocytosisCompletedNCT03770273Phase 2Results posted
• The Pharmacokinetics, Safety, and Tolerability of Abacavir/Dolutegravir/Lamivudine Dispersible and Immediate Release Tablets in HIV-1-Infected Children Less Than 12 Years of AgeCompletedNCT03760458Phase 1/2Results posted
• Long-Acting Cabotegravir Plus VRC-HIVMAB075-00-AB (VRC07-523LS) for Viral Suppression in Adults Living With HIV-1CompletedNCT03739996Phase 2Results posted
• 2017 A/H7N9 IIV RevaccinationCompletedNCT03738241Phase 2Results posted
• Evaluating the Safety and Pharmacokinetics of VRC07-523LS in the Sera and Mucosae of Healthy, HIV-Uninfected Adult ParticipantsCompletedNCT03735849Phase 1Results posted
• Investigational Therapeutics for the Treatment of People With Ebola Virus DiseaseCompletedNCT03719586Phase 2/3Results posted
• Dual bNAb Treatment in ChildrenCompletedNCT03707977Phase 1/2Results posted
• Pharmacokinetics and Safety of SAR441236TerminatedNCT03705169Phase 1Results posted
• Safety and Efficacy Study of Oral Fosfomycin Versus Oral Levofloxacin to Treat Complicated Urinary Syndromes (FOCUS)TerminatedNCT03697993Phase 4Results posted
• Safety/Efficacy Study of Seqirus A/H7N9 IIV With or Without MF59(R) Adjuvant to Prevent Avian InfluenzaCompletedNCT03682120Phase 2Results posted
• Andes Virus DNA Vaccine for the Prevention of Hantavirus Pulmonary Syndrome Using the PharmaJet Stratis(R) Needle-Free Injection Delivery DeviceCompletedNCT03682107Phase 1Results posted
• Development of Childhood Anti-Influenza ImmunityCompletedNCT03673345Phase 4Results posted
• Pharmacokinetic and Safety Study of a 90 Day Intravaginal Ring Containing TenofovirCompletedNCT03670355Phase 1Results posted
• Liver Transplantation With Tregs at UCSFTerminatedNCT03654040Phase 1/2Results posted
• Tocilizumab in Cardiac TransplantationCompletedNCT03644667Phase 2Results posted
• Defining Skin Immunity of a Bite of Key Insect Vectors in HumansCompletedNCT03641339Not applicableResults posted
• Phase 4 Comparative Trial of Benzathine Penicillin G for Treatment of Early Syphilis in Subjects With or Without HIV InfectionCompletedNCT03637660Phase 4Results posted
• The LATITUDE Study: Long-Acting Therapy to Improve Treatment SUccess in Daily LifECompletedNCT03635788Phase 3Results posted
• Evaluating HIV-1 Neutralization Antibody Breadth in Response to HIV gp120 Protein Vaccine in HIV-uninfected Adults With Quiescent Systemic Lupus ErythematosusCompletedNCT03618056Phase 1Results posted
• Thorough QT/QTC (TQT) Clinical Trial to Evaluate the Effect of Zoliflodacin on Cardiac Repolarization in Healthy Male and Female SubjectsCompletedNCT03613649Phase 1Results posted
• Safety and Immunogenicity of the Live Attenuated Zika Vaccine rZIKV/D4Δ30-713 in Flavivirus-naïve AdultsCompletedNCT03611946Phase 1Results posted
• Trial of Azithromycin vs. Doxycycline for the Treatment of Rectal Chlamydia in MSMCompletedNCT03608774Phase 4Results posted
• Evaluating the Infectivity, Safety and Immunogenicity of Respiratory Syncytial Virus Vaccines, RSV 6120/∆NS1 and RSV 6120/F1/G2/∆NS1, in RSV-Seropositive Children and RSV-Seronegative Infants and ChildrenCompletedNCT03596801Phase 1Results posted
• Clinical Study of a Single-Use, Point-of-Care Molecular Diagnostic Device for the Detection of Neisseria Gonorrhoeae (NG), Trichomonas Vaginalis (TV), and Chlamydia Trachomatis (CT) Utilizing Vaginal SwabsTerminatedNCT03596151Not applicableResults posted
• Evaluating the Safety of and Adherence to a Vaginal Matrix Ring Containing Dapivirine and Oral Emtricitabine/Tenofovir Disoproxil Fumarate in an Adolescent and Young Adult Female PopulationCompletedNCT03593655Phase 2Results posted
• 2013/2017 H7N9 Prime-Boost IntervalCompletedNCT03589807Phase 2Results posted
• Study on the Safety and Immunogenicity of Boostrix Vaccine in Pregnant Malian Women and Their InfantsCompletedNCT03589768Phase 2Results posted
• A Trial to Evaluate the Safety and Systems Biology Response of Ebolavirus Zaire Vaccine (ChAd3-EBO-Z)CompletedNCT03583606Phase 1Results posted
• Combination Therapy With 3BNC117 and 10-1074 in HIV-Infected IndividualsTerminatedNCT03571204Phase 1Results posted
• Phase I Study to Evaluate a Human Monoclonal Antibody (MAb) 10E8VLS Administered Alone or Concurrently With MAb VRC07-523LS Via Subcutaneous Injection in Healthy AdultsTerminatedNCT03565315Phase 1Results posted
• HIV-1-Gag Conserved-Element DNA Vaccine (p24CE) Vaccine StudyCompletedNCT03560258Phase 1/2Results posted
• H3N2 M2SR in Pediatric PopulationCompletedNCT03553940Phase 1Results posted
• A Double-Blind Placebo-Control Dose Escalating Study to Evaluate the Safety and Immunogenicity of dmLT by Oral, Sublingual and Intradermal Vaccination in Adults Residing in an Endemic AreaTerminatedNCT03548064Phase 1Results posted
• Safety and Efficacy of FMT in Individuals With One or More Recurrences of Clostridium Difficile Associated Disease (CDAD)TerminatedNCT03548051Phase 1/2Results posted
• Follow up of LEAP Participants and Their FamiliesCompletedNCT03546413Results posted
• Safety and Immunogenicity of Intranasal BPZE1 Vaccination in Healthy AdultsCompletedNCT03541499Phase 2Results posted
• Cockroach Immunotherapy in Children and AdolescentsCompletedNCT03541187Phase 2Results posted
• Phase I, Open-Label, Dose-Escalation Study of a Human Monoclonal Antibody, VRC-HIVMAB091-00-AB (N6LS), Administered Intravenously or Subcutaneously With or Without Recombinant Human Hyaluronidase PH20 (rHuPH20)CompletedNCT03538626Phase 1Results posted
• Safety, Immunogenicity, and Protective Efficacy of Two Regimens of Radiation Attenuated Plasmodium Falciparum NF54 Sporozoites (PfSPZ Vaccine) During Natural Transmission Season in Healthy African Adults in MaliCompletedNCT03510481Phase 1Results posted
• More Options for Children and Adolescents (MOCHA): Oral and Long-Acting Injectable Cabotegravir and Rilpivirine in HIV-Infected Children and AdolescentsCompletedNCT03497676Phase 1/2Results posted
• 2-5 Intermittent Caloric Restriction in HIVTerminatedNCT03489109Not applicableResults posted
• Safety and Pharmacokinetics of a Human Monoclonal Antibody, VRC-EBOMAB092-00-AB (MAb114), Administered Intravenously to Healthy AdultsCompletedNCT03478891Phase 1Results posted
• cAd3-Marburg Vaccine in Healthy AdultsCompletedNCT03475056Phase 1Results posted
• Evaluating the Safety and Immunogenicity of Env (A,B,C,A/E)/Gag (C) DNA and gp120 (A,B,C,A/E) Protein/GLA-SE HIV Vaccines, Given Individually or Co-administered, in Healthy, HIV-1-Uninfected AdultsCompletedNCT03409276Phase 1Results posted
• Evaluating the Safety and Pharmacokinetics of PC-1005 Administered Rectally to HIV-1 Seronegative AdultsCompletedNCT03408899Phase 1Results posted
• A Study to Evaluate the Safety, Tolerability and Plasma PK of a Single Oral Dose of Zoliflodacin in Healthy Male and Female VolunteersCompletedNCT03404167Phase 1Results posted
• NNITS-Nitazoxanide for Norovirus in Transplant Patients StudyCompletedNCT03395405Phase 2Results posted
• Effect of Dupilumab (Anti-IL4Rα) on the Host-Microbe Interface in Atopic DermatitisTerminatedNCT03389893Phase 4Results posted
• Challenge Infection of Healthy Adult Volunteers With RSV A2CompletedNCT03388645Phase 1Results posted
• Evaluating the Safety and Serum Concentrations of a Human Monoclonal Antibody, VRC-HIVMAB075-00-AB (VRC07-523LS), Administered in Multiple Doses and Routes to Healthy, HIV-uninfected AdultsCompletedNCT03387150Phase 1Results posted
• Evaluating the Infectivity, Safety, and Immunogenicity of a Respiratory Syncytial Virus Vaccine (RSV 6120/∆NS2/1030s) in RSV-Seropositive Children and RSV-Seronegative Infants and ChildrenCompletedNCT03387137Phase 1Results posted
• Evaluating the Pharmacokinetics, Feasibility, Acceptability, and Safety of Oral Pre-Exposure Prophylaxis for HIV Prevention During Pregnancy and PostpartumCompletedNCT03386578Phase 2Results posted
• Selective Estrogen Receptor Modulators to Enhance the Efficacy of Viral Reactivation With Histone Deacetylase InhibitorsCompletedNCT03382834Phase 2Results posted
• Evaluating the Safety and Immunogenicity of an HIV Vaccine (gp145 C.6980) in Healthy, HIV-Uninfected Adults in the United StatesCompletedNCT03382418Phase 1Results posted
• Safety and Tolerability of AAV8 Delivery of a Broadly Neutralizing Antibody in Adults Living With HIV: a Phase 1, Dose-escalation TrialActive, not recruitingNCT03374202Phase 1Results posted
• Minocycline Pharmacokinetics (ACUMIN)CompletedNCT03369951Phase 4Results posted
• A Single Dose of Pembrolizumab in HIV-Infected PeopleTerminatedNCT03367754Phase 1Results posted
• Placebo-Controlled Trial of Antibiotic Therapy in Adults With Suspect Lower Respiratory Tract Infection (LRTI) and a Procalcitonin LevelTerminatedNCT03341273Not applicableResults posted
• Evaluating the Pharmacokinetics, Safety, and Tolerability of Doravirine (MK-1439) and Doravirine/Lamivudine/Tenofovir Disoproxil Fumarate (MK-1439A) in HIV-1-Infected Children and AdolescentsCompletedNCT03332095Phase 1/2Results posted
• Bilateral Orthotopic Lung Transplant - Bone Marrow TransplantCompletedNCT03330795Phase 1/2Results posted
• Age and Response to Flu VaccinesTerminatedNCT03328325Phase 4Results posted
• Co-Administration of AS03 Adjuvanted A/H7N9 IIV With IIV4CompletedNCT03318315Phase 2Results posted
• Sanofi 2017 H7N9 With/Without AS03 in Adults/ElderlyCompletedNCT03312231Phase 2Results posted
• Asymptomatic Congenital CMV TreatmentTerminatedNCT03301415Phase 2Results posted
• A Trial of Mepolizumab Adjunctive Therapy for the Prevention of Asthma Exacerbations in Urban ChildrenCompletedNCT03292588Phase 2Results posted

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