National Institute of Allergy and Infectious Diseases (NIAID): all 2,445 studies

Page 1 of 25. Open to participants first (182), then studies with results posted, then the rest; newest registration first within each.

• A Clinical Study to Assess the Efficacy of Weekly Doxycycline Prophylaxis to Reduce Bacterial Sexually Transmitted Infections (STI) in Young African WomenNot yet recruitingNCT07884240Phase 3
• A Clinical Study of Ixazomib to Reactivate HIV and Reduce HIV Reservoir SizeNot yet recruitingNCT07881809Phase 2
• Firefighter's Longitudinal Airway and Respiratory Exposome/Multiome Study (FLARES)Enrolling by invitationNCT07867184
• Positron Emission Tomography and Organ-Specific Changes in Participants Co-Enrolled in NIH Studies of Plasmodium Vivax Controlled Human Malaria InfectionNot yet recruitingNCT07859800Not applicable
• A Clinical Study of the HCMV-TB Vaccine Candidate VIR-1778 in Healthy AdultsNot yet recruitingNCT07818824Phase 1
• A Clinical Study to Evaluate the Safety and Immunogenicity of a Higher Dose of the Study Vaccine, VIR-1388, in HCMV-seropositive Adult Participants Without HIVNot yet recruitingNCT07801456Phase 1
• Expanding HOPE LiverRecruitingNCT07778459
• Base-Edited Hematopoietic Stem/Progenitor Cell Gene Therapy for Treatment of CXCR4-WHIMEnrolling by invitationNCT07775313Phase 1/2
• Phase 1 Study of CH505 HIV Vaccine Nanoparticles and mRNA Boosters in Healthy AdultsRecruitingNCT07757802Phase 1
• Phase 1 Challenge Study Using rDEN2delta30-7169 to Evaluate Host-Pathogen Interactions in Primary, Homotypic, and Heterotypic Dengue Virus InfectionRecruitingNCT07706686Phase 1
• Safety and Immunogenicity of Chimeric Hemagglutinin mRNA Vaccine CandidatesNot yet recruitingNCT07703514Phase 1
• A Safety, Reactogenicity and Immunogenicity Trial of RVX-sCPD9 Booster Intranasal COVID-19 VaccineNot yet recruitingNCT07703475Phase 1
• Natural History of Trisomy 8-Associated Autoinflammatory Disease (TRIAD) and Related DisordersRecruitingNCT07683104
• A Safety Trial to Evaluate an Orally Ingested Yeast Modified to Express a Tetra-specific Anti-toxin for Clostridioides DifficileNot yet recruitingNCT07649096Phase 1
• Beginning to Assess an Appropriate CONtrol for Oral Food Challenges in Alpha-Gal Syndrome (CoFAR-13) - BeACON4AGRecruitingNCT07611435Phase 2
• A Trial of Stratified Patient-Centered Treatment Regimens for Active TB (SPECTRA-TB)Not yet recruitingNCT07595042Phase 2
• A Trial to Evaluate the Safety and Tolerability of DV700P-RNA and DV701B1.1-RNA Immunization in Combination With Antiretroviral Analytical Treatment Interruption (ATI) in People Living With HIV for Elicitation of V3-glycan AntibodiesRecruitingNCT07569029Phase 1
• Early Signals of the Transition From Immune Quiescence to Activation in the Liver Allograft Microenvironment and in the CirculationRecruitingNCT07549503Phase 2
• A Safety and Immunogenicity Trial of OCU500, ChAd36 Vector Encoding SARS-CoV-2 Spike Vaccine Via Intranasal and Inhalational Routes in Previously Vaccinated AdultsRecruitingNCT07536308Phase 1
• LYmph Node eXamination in Cat Allergen ImmunotherapyRecruitingNCT07447869Early Phase 1
• Natural History of Dysregulation and Aging of the Immune System in People With Trisomy 21 With and Without ThymectomyRecruitingNCT07416201
• A Study of Safety and Drug Levels of ePGT121v1-LS, PGDM1400LS, and VRC07-523LS in Adult Participants Without HIV-1RecruitingNCT07390955Phase 1
• Clinical Trial to Evaluate the Safety and Immunogenicity of the V2 Apex-Directed Immunogens DV201P-RNA and DV202B1-RNA in Adult Participants Without HIVRecruitingNCT07390474Phase 1
• Dasatinib for HIV-1 Reservoir ReductionRecruitingNCT07342491Phase 1
• Study of Oral Food Challenge Biomarkers (SAFER)RecruitingNCT07279467
• THREAT: Testing Harms Related to Exposure to Allergenic and Epithelial ToxinsRecruitingNCT07271381Not applicable
• Evaluating the Safety and Tolerability of Baricitinib in Patients With Job Syndrome With Lupus-Like Disease and/or Atopic DermatitisRecruitingNCT07262983Phase 1
• Small Trial of Alendronate Impact on the Reservoir of HIVRecruitingNCT07216794Phase 2
• Rechallenge With a Low Pathogenicity Avian H10N7 Influenza Virus in Healthy Human Volunteers Previously Challenged With H10N7 InfluenzaEnrolling by invitationNCT07215871Phase 1
• BPL-1357 Against H1N1 Influenza Virus ChallengeRecruitingNCT07215858Phase 2
• Randomized Stepped Wedge Study of Emapalumab in APECED EnteritisRecruitingNCT07202598Phase 2
• Steroid Treatment for Severe Acute Respiratory Infection (STAR) TrialNot yet recruitingNCT07199192Phase 4
• First-in-Human Study of VNT-101: Safety, Tolerability, and PharmacokineticsRecruitingNCT07169318Phase 1
• A Study of Daily Rifapentine Combined With Isoniazid (1HP) for Tuberculosis Prevention in Children Less Than 13 Years of Age With and Without HIVRecruitingNCT07124559Phase 1/2
• Part B- G1X-CGD (Lentiviral Vector Transduced CD34+ Cells) in Patients With X-Linked Chronic Granulomatous DiseaseEnrolling by invitationNCT07113743Phase 1/2
• Quadrivalent Influenza HA Stem Vaccine VRC-FLUMOS0122-00-VP (SteMos1) With and Without ALFQ Adjuvant in Healthy AdultsRecruitingNCT07111078Phase 1
• pH1N1 Blinded Challenge StudyRecruitingNCT07110532Phase 1
• Tocilizumab Discontinuation Versus Dose Reduction for Patients With Well-Controlled Giant Cell ArteritisRecruitingNCT07108387Phase 2
• Ublituximab in Autoantibody Positive Immune Mediated Necrotizing MyopathyRecruitingNCT07103746Phase 2
• Microbiome and Atopy in MaliRecruitingNCT07051902
• Study of the Pharmacokinetics and Safety of Glecaprevir/Pibrentasvir Initiated in Pregnancy in Women With Hepatitis C With and Without HIVRecruitingNCT07040319Phase 1/2
• The Esophageal String Test as a Diagnostic Screening Tool for Eosinophilic Esophagitis Among Africans With Dysphagia in Mali and the United StatesRecruitingNCT07027826Not applicable
• Efficacy of Tezepelumab in Peanut Oral ImmunotherapyRecruitingNCT07015996Phase 2
• A Study to Evaluate the Safety and Antiviral Activity of Two Human Monoclonal Antibodies (VRC07-523LS and PGT121.414.LS) During Analytic Treatment Interruption in Participants Living With HIV Who Initiated ART During Acute/Early HIV-1 InfectionNot yet recruitingNCT06987318Phase 1
• Repeat PET/CT Imaging in People With CAPS and Anakinra-Induced Amyloidosis Using an Amyloid-Reactive Peptide to Measure Changes in Organ-Specific Amyloid LoadRecruitingNCT06974877Phase 1
• Base Editing Hematopoietic Stem Cell and T Cell Gene Therapy for CD40L-HyperIgM Syndrome: Single Patient StudyRecruitingNCT06959771Phase 1/2
• Improving Deceased-Donor Kidney Transplant Outcomes Via a Single Intragraft Injection of C1 Esterase Inhibitor (IMPROVE TRIAL)RecruitingNCT06919003Phase 2
• Treatment of Antibody-Mediated Rejection (ABMR) With CarBelRecruitingNCT06918990Phase 1
• Epstein-Barr Virus (EBV) gH/gL/gp42-Ferritin Nanoparticle Vaccine With or Without gp350-Ferritin in Healthy Adults With or Without EBV InfectionRecruitingNCT06908096Phase 1
• Immunologic and Virologic Parameters During Analytical Treatment Interruption Following Combination bNAb Therapy During Suppressive ARTEnrolling by invitationNCT06908083Phase 1
• Evaluating the Dose, Safety, Tolerability, and Immunogenicity of Mosaic Hexavalent Influenza Vaccine VRCFLUMOS0116-00-VP (FluMos-v2) With and Without ALFQ Adjuvant in Healthy AdultsRecruitingNCT06863142Phase 1
• Base-Edited Hematopoietic Stem/Progenitor Cell X-Linked Severe Combined Immunodeficiency Gene TherapyEnrolling by invitationNCT06851767Phase 1/2
• EVR and EPO for Liver Transplant ToleranceRecruitingNCT06832189Phase 1
• Lenacapavir Intensification to Disrupt HIV Reservoirs in Virologically Suppressed People With HIV Receiving Antiretroviral TherapyRecruitingNCT06819176Phase 1
• Clinical Trial to Evaluate the Safety and Immunogenicity of a Priming Regimen of 426c.Mod.Core-C4b Followed by HxB2.WT.Core-C4b Boosts, Both Adjuvanted With 3M-052 AF + Alum, in Adult Participants Without HIV and in Overall Good HealthRecruitingNCT06796686Phase 1
• A Biorepository of Multiple Allergic Diseases (MADREP) With Longitudinal Follow-UpRecruitingNCT06732414
• Study of the ITK Inhibitor Soquelitinib to Reduce Lymphoproliferation and Improve Cytopenias in Autoimmune Lymphoproliferative Syndrome (ALPS)-FAS PatientsRecruitingNCT06730126Phase 2
• Characterization of Human Immune Signatures to Zoonotic Virus Exposure in CambodiaRecruitingNCT06680843
• Clinical Trial to Evaluate the Safety and Immunogenicity of Hiltonol, Poly-ICLC-adjuvanted CD40.HIVRI.Env (VRIPRO) in Adult Participants Who Previously Participated in HVTN 706RecruitingNCT06665646Phase 1
• Induced Blood-Stage Malaria in Healthy Malaria-Naive Adults to Assess the Safety and Infectivity of Plasmodium Vivax Challenge Agent and Evaluate Transmission in Mosquito Feeding AssaysRecruitingNCT06607003Phase 1
• Safety and Pharmacokinetics Study of PGT121.414.LS Alone and in Combination With VRC07-523LS in Infants Exposed to HIV-1RecruitingNCT06517693Phase 1
• Targeted Investigation of Microbiome 2 Treat Atopic Dermatitis (TIME-2)RecruitingNCT06504160Phase 1
• Modeling Host-Pathogen Interaction Using Lymphoid OrganoidsRecruitingNCT06479837
• Belatacept in Heart TransplantationRecruitingNCT06478017Phase 2
• Dupilumab as Add-On Therapy for Hypereosinophilic Syndrome With Partial Clinical Response to Eosinophil-Depleting Biologic AgentsRecruitingNCT06477653Phase 2
• Belumosudil to Block Chronic Lung Allograft Dysfunction (CLAD) in High Risk Lung Transplant RecipientsRecruitingNCT06476132Phase 2
• Pregnancy Registry in MaliRecruitingNCT06468319
• Hemophagocytic Lymphohistiocytosis (HLH) Evaluation and Research of Clinical, ImmUnoLogic and TranscriptomE StudyRecruitingNCT06339177
• Base Editing for Mutation Repair in Hematopoietic Stem & Progenitor Cells for X-Linked Chronic Granulomatous DiseaseRecruitingNCT06325709Phase 1/2
• Expanding Liver Transplant Immunosuppression Minimization Via EverolimusRecruitingNCT06280950Phase 2
• pCCLCHIM-p47 (Lentiviral Vector Transduced CD34 Plus Cells) in Patients With p47 Autosomal Recessive Chronic Granulomatous Disease (AR-CGD)Enrolling by invitationNCT06253507Phase 1/2
• Trial of Novel Regimens for the Treatment of Pulmonary TuberculosisRecruitingNCT06192160Phase 2
• Detection and Characterization of Neurologic Manifestations of Inborn and Acquired Errors of ImmunityRecruitingNCT06169150
• Protocol CAUSE-03 / CHEETAHRecruitingNCT06136091
• Establishment of Biobank of Nasal Epithelium Samples From Healthy VolunteersNot yet recruitingNCT06120244
• Cardamom and Topical Roseomonas in Atopic DermatitisRecruitingNCT06096857Phase 2
• Cytomegalovirus (CMV) Vaccine in Orthotopic Liver Transplant CandidatesRecruitingNCT06075745Phase 2
• CAR-T Cell Therapy for Desensitization in Kidney TransplantationRecruitingNCT06056102Phase 1
• Advancing Transplantation Outcomes in ChildrenRecruitingNCT06055608Phase 2
• Tocilizumab in Lung TransplantationRecruitingNCT06033196Phase 2
• High vs.Standard Dose Influenza Vaccine in Pediatric Solid Organ Transplant (SOT) RecipientsRecruitingNCT05947071Phase 2
• Assessment of Biomarker-Guided CNI Substitution In Kidney TransplantationRecruitingNCT05917522Phase 2
• A Clinical Trial of Combination HIV-Specific Broadly Neutralizing Monoclonal Antibodies Combined With ART Initiation During Acute HIV Infection to Induce HIV RemissionRecruitingNCT05719441Phase 2
• Daratumumab in Primary Antiphospholipid SyndromeRecruitingNCT05671757Phase 1/2
• Study of Oral and Long-Acting Injectable Cabotegravir and Rilpivirine in Virologically Suppressed Children Living With HIV-1, Two to Less Than 12 Years of AgeRecruitingNCT05660980Phase 1/2
• A Repository to Study Host-Microbiome Interactions in Health and DiseaseRecruitingNCT05656378
• Evaluating the Genetics and Immunology of Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis (PFAPA) Syndrome and Other Tonsil DisordersRecruitingNCT05656365
• Early Metabolic Effects of Antiretroviral Drugs in Healthy volUnteers: a Phase 2 Randomized StudyRecruitingNCT05652478Phase 2
• A Single-arm, Dose-escalation Trial of Long-acting Recombinant Human IL-7 (NT-I7, Efineptakin Alfa) for Idiopathic CD4 LymphopeniaRecruitingNCT05600920Phase 1/2
• Safety and Immunogenicity of Recombinant Varicella Zoster Virus Vaccine in People With HIV Who Have a CD4 Count Less Than 300 or Greater Than or Equal to 300 and a Healthy Control PopulationRecruitingNCT05580458Phase 1/2
• Allogeneic Hematopoietic Stem Cell Transplantation for Chronic Granulomatous Disease (CGD) With an Alemtuzumab, Busulfan and TBI-based Conditioning Regimen Combined With Cytokine (IL-6, +/- IFN-gamma) AntagonistsRecruitingNCT05463133Phase 1/2
• Evaluate the Efficacy and Safety of Ruxolitinib on Hair Regrowth in Patients With Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy (APECED)-Associated Alopecia AreataRecruitingNCT05398809Phase 2
• Trial of a Six-Month Regimen of High-Dose Rifampicin, High-Dose Isoniazid, Linezolid, and Pyrazinamide Versus a Standard Nine-Month Regimen for the Treatment of Adults and Adolescents With Tuberculous MeningitisRecruitingNCT05383742Phase 2
• Fecal Microbiota Transplantation for Chronic Granulomatous Disease-Associated ColitisRecruitingNCT05333471Phase 1/2
• Registry of Asthma Characterization and Recruitment 3 (RACR3)RecruitingNCT05272241
• Respiratory Virus Sampling and RepositoryRecruitingNCT05266222
• VIBRANT: VIB4920 for Active Lupus NephritisRecruitingNCT05201469Phase 2
• NADPH Oxidase Correction in mRNA-transfected Granulocyte-enriched Cells in Chronic Granulomatous Disease (CGD)RecruitingNCT05189925Phase 1
• Human Immune Response to Ixodes Scapularis Tick BitesRecruitingNCT05036707Phase 1/2
• Natural History, Epidemiology and Pathogenesis of Severe HPV-Related Diseases (Neptune)RecruitingNCT05026138

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