National Institute of Allergy and Infectious Diseases (NIAID): Infections trials

The registry lists 308 Infections studies with National Institute of Allergy and Infectious Diseases (NIAID) as lead sponsor. 12 are open to participants now and 41 have results posted.

Phase 1 72Phase 2 88Phase 3 44Phase 4 5No phase 108(a study in two phases counts in both)

Studies

Page 1 of 4. Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Rechallenge With a Low Pathogenicity Avian H10N7 Influenza Virus in Healthy Human Volunteers Previously Challenged With H10N7 InfluenzaEnrolling by invitationNCT07215871Phase 1
• High vs.Standard Dose Influenza Vaccine in Pediatric Solid Organ Transplant (SOT) RecipientsRecruitingNCT05947071Phase 2
• NADPH Oxidase Correction in mRNA-transfected Granulocyte-enriched Cells in Chronic Granulomatous Disease (CGD)RecruitingNCT05189925Phase 1
• Natural History, Epidemiology and Pathogenesis of Severe HPV-Related Diseases (Neptune)RecruitingNCT05026138
• Pathogenesis and Genetics of Disseminated or Refractory CoccidioidomycosisRecruitingNCT02190266
• Diagnosis and Management of Inflammatory and Infectious DiseasesRecruitingNCT00557726
• Evaluation of Patients With Immune Function AbnormalitiesRecruitingNCT00128973
• Evaluation, Treatment, and Follow-up of Patients With Lyme DiseaseRecruitingNCT00028080
• Natural History, Management, and Genetics of the Hyperimmunoglobulin E Recurrent Infection Syndrome (HIES)RecruitingNCT00006150
• Recruitment and Apheresis Collection of Peripheral Blood Hematopoietic Stem Cells, Mononuclear Cells and GranulocytesRecruitingNCT00001405
• Detection and Characterization of Host Defense DefectsRecruitingNCT00001355
• Evaluation and Long-Term Follow-up of Patients With Inflammatory DisordersEnrolling by invitationNCT00001351
• A Clinical Trial to Evaluate the Safety and Immunogenicity of BG505 MD39.3, BG505 MD39.3 gp151, and BG505 MD39.3 gp151 CD4KO HIV Trimer mRNA Vaccines in Healthy, HIV-uninfected Adult ParticipantsActive, not recruitingNCT05217641Phase 1Results posted
• Experimental Human Infection With Neisseria Gonorrhoeae (LptA Trial)CompletedNCT04870138Phase 1Results posted
• A Study of SARS CoV-2 Infection and Potential Transmission in Individuals Immunized With Moderna COVID-19 VaccineCompletedNCT04811664Phase 3Results posted
• Evaluating the Safety and Immunogenicity of AGS-v PLUS, a Universal Mosquito-Borne Disease and Mosquito Control VaccineCompletedNCT04009824Phase 1Results posted
• Clinical Study of a Diagnostic Device for NG, TV and CT in WomenCompletedNCT03852316Not applicableResults posted
• Experimental Human Infection With Neisseria GonorrhoeaeCompletedNCT03840811Phase 1Results posted
• Safety and Efficacy Study of Oral Fosfomycin Versus Oral Levofloxacin to Treat Complicated Urinary Syndromes (FOCUS)TerminatedNCT03697993Phase 4Results posted
• Challenge Infection of Healthy Adult Volunteers With RSV A2CompletedNCT03388645Phase 1Results posted
• Placebo-Controlled Trial of Antibiotic Therapy in Adults With Suspect Lower Respiratory Tract Infection (LRTI) and a Procalcitonin LevelTerminatedNCT03341273Not applicableResults posted
• Asymptomatic Congenital CMV TreatmentTerminatedNCT03301415Phase 2Results posted
• YCFM (Youth Correctional Facilities Males)CompletedNCT03249935Phase 2Results posted
• VRC 705: A Zika Virus DNA Vaccine in Healthy Adults and AdolescentsCompletedNCT03110770Phase 2Results posted
• Evaluating the Safety and Pharmacokinetics of Maraviroc in HIV-1-Exposed Infants at Risk of Acquiring HIV-1 InfectionCompletedNCT02778204Phase 1Results posted
• Evaluating the Safety and Efficacy of the VRC01 Antibody in Reducing Acquisition of HIV-1 Infection Among Men and Transgender Persons Who Have Sex With MenCompletedNCT02716675Phase 2Results posted
• Safety and Therapeutic Efficacy of the VRC01 Antibody in Patients Who Initiated Antiretroviral Therapy During Early Acute HIV InfectionCompletedNCT02664415Phase 2Results posted
• Evaluating the Safety and Efficacy of the VRC01 Antibody in Reducing Acquisition of HIV-1 Infection in WomenCompletedNCT02568215Phase 2Results posted
• A Safety and Immune Response Study of 2 Experimental HIV VaccinesCompletedNCT02404311Phase 1/2Results posted
• Putative Investigational Therapeutics in the Treatment of Patients With Known Ebola InfectionCompletedNCT02363322Phase 1/2Results posted
• Plerixafor Versus G-CSF in the Treatment of People With WHIM SyndromeCompletedNCT02231879Phase 2/3Results posted
• Evaluating the Safety and Effectiveness of Interferon-Free Treatment of Hepatitis C Virus Infection in HIV-Coinfected Adults on Antiretroviral TherapyTerminatedNCT02194998Phase 2Results posted
• Safety and Effectiveness of Low-Dose Methotrexate for Reducing Inflammation in HIV-Infected Adults on ARV MedicationsCompletedNCT01949116Phase 2Results posted
• Safety and Pharmacokinetics of Raltegravir in HIV-1-Exposed Newborn Infants at Risk of Acquiring HIV-1 InfectionCompletedNCT01780831Phase 1Results posted
• Valganciclovir Therapy in Infants and Children With Congenital CMV Infection and Hearing LossCompletedNCT01649869Phase 2Results posted
• The SCOUT Study: "Short Course Therapy for Urinary Tract Infections in Children"CompletedNCT01595529Phase 2Results posted
• Evaluating the Safety and Tolerability of Antiretroviral Drug Regimens Used as Pre-Exposure Prophylaxis to Prevent HIV Infection in At-Risk Men Who Have Sex With Men and in At-Risk WomenCompletedNCT01505114Phase 2Results posted
• Evaluating the Effectiveness of Boceprevir, Pegylated-Interferon Alfa 2b and Ribavirin in Treating Hepatitis C Virus (HCV) Infection in Adults With HIV and HCV InfectionCompletedNCT01482767Phase 3Results posted
• Quadrivalent HPV Vaccine to Prevent Anal HPV in HIV-infected Men and WomenCompletedNCT01461096Phase 3Results posted
• Brief Rifapentine-Isoniazid Evaluation for TB Prevention (BRIEF TB)CompletedNCT01404312Phase 3Results posted
• Nitazoxanide Plus Ribavirin and Peginterferon for Therapy of Treatment Naive HCV Genotype 1 and HIV Coinfected SubjectsCompletedNCT00991289Phase 2Results posted
• Safety and Immune Response of a Rotavirus Vaccine in HIV-infected and Uninfected Children Born to HIV-infected MothersCompletedNCT00880698Phase 2Results posted
• Uncomplicated Skin and Soft Tissue Infections Caused by Community-Associated Methicillin-Resistant Staphylococcus AureusCompletedNCT00730028Phase 2Results posted
• Effect of Ranitidine on Hyper-IgE Recurrent Infection (Job's) SyndromeTerminatedNCT00527878Phase 2Results posted
• Short-Term vs. Long-Term Valganciclovir Therapy for Symptomatic Congenital CMV InfectionsCompletedNCT00466817Phase 3Results posted
• Pioglitazone to Treat Fatty Liver in People With HIV InfectionCompletedNCT00441272Phase 2Results posted
• Development of Immune Globulin Treatment for Avian FluTerminatedNCT00383071Phase 2Results posted
• Drug Treatment Combined With Drug and Risk Reduction Counseling to Prevent of HIV Infection and Death Among Injection Drug UsersTerminatedNCT00270257Phase 3Results posted
• Effect of Intermittent Aldesleukin Treatment With or Without Anti-HIV Drugs in HIV Infected PeopleCompletedNCT00110812Phase 2Results posted
• Anti-HIV Drugs for Treating Infants Who Acquired HIV Infection at BirthCompletedNCT00102960Phase 3Results posted
• Cyclosporine A in Combination With Abacavir Sulfate, Lamivudine, and Zidovudine and Lopinavir/Ritonavir in HIVCompletedNCT00084149Phase 2Results posted
• Peginterferon Alpha-2b And Ribavirin to Treat Hepatitis C in HIV-Infected PatientsCompletedNCT00018031Phase 2Results posted
• An International Study to Evaluate Recombinant Interleukin-2 in HIV Positive Patients Taking Anti-retroviral TherapyCompletedNCT00004978Phase 3Results posted
• A Study of Doxycycline to Treat Chlamydial InfectionCompletedNCT05840159Phase 4
• Community Dynamics of Malaria Transmission in Humans and Mosquitoes in Fleh-la and Marshansue, Salala District, Bong County, LiberiaActive, not recruitingNCT04704674
• Malaria Transmission in Humans and Mosquitoes at the Area of Sabou, Burkina FasoCompletedNCT04650815
• Surveillance of Individuals Following SARS-CoV-2 InfectionCompletedNCT04383444
• Plasmodium and Other Parasites in Pregnant Women and Children Around Margibi and Montserrado Counties, LiberiaCompletedNCT03719599
• A Systems Biology Approach to Malaria ImmunityCompletedNCT03014258Phase 1
• Feasibility of Measuring Immune Resp, Activation in Foreskin/Mucosa in HIV-, Uncircumcised High-HIV-risk MSM, Lima PeruCompletedNCT02630082Not applicable
• Collection of Plasma From People Who Recovered From or Were Vaccinated to Emerging Infectious DiseasesCompletedNCT02338986
• Human Immunity Against Staphylococcus Aureus Skin InfectionCompletedNCT02262819Phase 1
• Immune Responses to Mycobacterium Tuberculosis (Mtb) in People With Latent Tuberculosis Infection With or Without Concomitant Helminth InfectionTerminatedNCT02225158
• Zoonotic Influenza Infections of Swine Origin at Ohio Agricultural FairsCompletedNCT02124096
• VRC 601: A Phase I, Open-Label, Dose-Escalation Study of the Safety and Pharmacokinetics of a Human Monoclonal Antibody, VRC HIVMAB060-00-AB (VRC01), With Broad HIV-1 Neutralizing Activity, Administered Intravenously or Subcutaneously to HIV-Infected...CompletedNCT01950325Phase 1
• Sildenafil for PNTM InfectionCompletedNCT01853540Phase 1/2
• Human Rhinovirus Infection and Airway Remodeling MediatorsTerminatedNCT01847768Not applicable
• Gene Expression in HIV and Tuberculosis Co-infectionCompletedNCT01611402
• Effect of Filarial Infection on Immune Responses in Latent TuberculosisCompletedNCT01547884
• Evaluating the Safety and Immune Response to Two Pneumococcal Vaccines in HIV-Infected Pregnant WomenWithdrawnNCT01443117Phase 2
• DAS181 in Patients With ParainfluenzaWithdrawnNCT01441024Phase 2
• Multiplex Microarray Chip-Based Diagnosis of Respiratory InfectionsTerminatedNCT01212042
• Evaluation of the Safety and Immunogenicity of a Live Attenuated Virus Vaccine for the Prevention of H2N3 InfluenzaCompletedNCT01175122Phase 1
• Evaluation of the Cellular Pharmacology of Tenofovir and Emtricitabine According to HIV Infection StatusCompletedNCT01040091Phase 1
• A Phase I Study of Mozobil in the Treatment of Patients With WHIMSCompletedNCT00967785Phase 1/2
• Host Factors in Invasive and Recurrent Staphylococcus Aureus InfectionTerminatedNCT00911430
• Safety of Acidform Lubricant in HIV-Uninfected WomenCompletedNCT00850837Phase 1
• Hepatitis B and HIV Co-Infection in Patients in UgandaCompletedNCT00782158
• Bone Mineral Density Substudy - An Ancillary Study to MTN-003CompletedNCT00729573
• Safety and Tolerability of a Therapeutic DNA Dendritic Cell Vaccine in HIV-Infected Children, Adolescents, and Young AdultsWithdrawnNCT00614640Phase 1/2
• Interventional Study of Mucosal and Antimicrobial Responses to Repeated Vaginal Applications of Tenofovir Gel in HIV Uninfected WomenCompletedNCT00594373Phase 1
• Influenza in People With Normal and Weakened Immune SystemsCompletedNCT00533182
• Study of Chlorhexidine as the Hub Antiseptic to Prevent Catheter Related Infections in Newborn InfantsStatus unknownNCT00516360Phase 4
• Safety and Effectiveness of an HIV DNA Vaccine Followed by an HIV Adenoviral Vector Vaccine for Prevention of HIV Infection in the Americas and AfricaWithdrawnNCT00498056Phase 2
• Safety of and Immune Response to a DNA HIV Vaccine Followed By Boosting With One of Two Serotypes of Adenoviral Vector HIV Vaccine in Healthy AdultsCompletedNCT00472719Phase 1
• Safety of and Immune Response to an HIV DNA Plasmid Vaccine Followed by HIV Adenoviral Vector Vaccine in Healthy African AdultsWithdrawnNCT00415649Phase 2
• Determining Responses to Two Different Vaccines in HIV and HCV Infected IndividualsCompletedNCT00393276Phase 1
• Examining Factors That May Influence Resistance to HIV-1 InfectionCompletedNCT00351442
• Changes in HIV Viral Load in Patients Undergoing Treatment for FilariasisCompletedNCT00344279
• New Techniques for Using a Saline Wash as a Diagnostic Tool for Pneumocystis PneumoniaCompletedNCT00342589
• Host Response to Infection and Treatment in Lymphatic Filarial Disease in IndiaCompletedNCT00342576
• Surveillance of Streptococcal Infections in Children in IndiaCompletedNCT00342199
• The Effect of Parasitic Worm Infections on the Immune Response to Tuberculosis BacteriaCompletedNCT00342017
• Immune Response Regulation in People Infected Concurrently With Malarial and Filarial ParasitesCompletedNCT00341666
• Doxycycline to Treat Mansonella Perstans Infection in Patients With and Without Lymphatic FilariasisCompletedNCT00340691Phase 2
• Observational Study of Changes in Fat Distribution and Blood Metabolites in HIV Infected AdultsStatus unknownNCT00331448
• CMV Infection in Adolescent MalesTerminatedNCT00302029
• Acute HIV Infection Observational StudyCompletedNCT00296660
• Estimating the Incidence of HIV Infection Among Men Who Have Sex With Men in Peru and EcuadorCompletedNCT00279331
• Prevalence of HIV and Other Sexually Transmitted Infections Among Female Sex Workers and Miners in Honghe Prefecture, Yunnan Province, ChinaCompletedNCT00278499