National Institute of Allergy and Infectious Diseases (NIAID): Communicable Diseases trials

The registry lists 163 Communicable Diseases studies with National Institute of Allergy and Infectious Diseases (NIAID) as lead sponsor. 3 are open to participants now and 25 have results posted.

Phase 1 37Phase 2 41Phase 3 25Phase 4 2No phase 62(a study in two phases counts in both)

Studies

Page 1 of 2. Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• High vs.Standard Dose Influenza Vaccine in Pediatric Solid Organ Transplant (SOT) RecipientsRecruitingNCT05947071Phase 2
• Admission and Management of Occupational or Other Exposures to Biodefense/Bioterrorism Agents or to Epidemic/Emerging Infectious DiseasesRecruitingNCT01200953
• Studies of the Pathogenesis of HIV Infection in Human Peripheral Blood Cells and/or Body Fluids in People Living With and Without HIVRecruitingNCT00001281
• A Clinical Trial to Evaluate the Safety and Immunogenicity of BG505 MD39.3, BG505 MD39.3 gp151, and BG505 MD39.3 gp151 CD4KO HIV Trimer mRNA Vaccines in Healthy, HIV-uninfected Adult ParticipantsActive, not recruitingNCT05217641Phase 1Results posted
• Experimental Human Infection With Neisseria Gonorrhoeae (LptA Trial)CompletedNCT04870138Phase 1Results posted
• A Study of SARS CoV-2 Infection and Potential Transmission in Individuals Immunized With Moderna COVID-19 VaccineCompletedNCT04811664Phase 3Results posted
• Evaluating the Safety and Immunogenicity of AGS-v PLUS, a Universal Mosquito-Borne Disease and Mosquito Control VaccineCompletedNCT04009824Phase 1Results posted
• Clinical Study of a Diagnostic Device for NG, TV and CT in WomenCompletedNCT03852316Not applicableResults posted
• Experimental Human Infection With Neisseria GonorrhoeaeCompletedNCT03840811Phase 1Results posted
• Challenge Infection of Healthy Adult Volunteers With RSV A2CompletedNCT03388645Phase 1Results posted
• Placebo-Controlled Trial of Antibiotic Therapy in Adults With Suspect Lower Respiratory Tract Infection (LRTI) and a Procalcitonin LevelTerminatedNCT03341273Not applicableResults posted
• VRC 705: A Zika Virus DNA Vaccine in Healthy Adults and AdolescentsCompletedNCT03110770Phase 2Results posted
• Evaluating the Safety and Pharmacokinetics of Maraviroc in HIV-1-Exposed Infants at Risk of Acquiring HIV-1 InfectionCompletedNCT02778204Phase 1Results posted
• Evaluating the Safety and Efficacy of the VRC01 Antibody in Reducing Acquisition of HIV-1 Infection Among Men and Transgender Persons Who Have Sex With MenCompletedNCT02716675Phase 2Results posted
• Safety and Therapeutic Efficacy of the VRC01 Antibody in Patients Who Initiated Antiretroviral Therapy During Early Acute HIV InfectionCompletedNCT02664415Phase 2Results posted
• Evaluating the Safety and Efficacy of the VRC01 Antibody in Reducing Acquisition of HIV-1 Infection in WomenCompletedNCT02568215Phase 2Results posted
• Putative Investigational Therapeutics in the Treatment of Patients With Known Ebola InfectionCompletedNCT02363322Phase 1/2Results posted
• Evaluating the Safety and Effectiveness of Interferon-Free Treatment of Hepatitis C Virus Infection in HIV-Coinfected Adults on Antiretroviral TherapyTerminatedNCT02194998Phase 2Results posted
• Safety and Pharmacokinetics of Raltegravir in HIV-1-Exposed Newborn Infants at Risk of Acquiring HIV-1 InfectionCompletedNCT01780831Phase 1Results posted
• Valganciclovir Therapy in Infants and Children With Congenital CMV Infection and Hearing LossCompletedNCT01649869Phase 2Results posted
• The SCOUT Study: "Short Course Therapy for Urinary Tract Infections in Children"CompletedNCT01595529Phase 2Results posted
• Nitazoxanide Plus Ribavirin and Peginterferon for Therapy of Treatment Naive HCV Genotype 1 and HIV Coinfected SubjectsCompletedNCT00991289Phase 2Results posted
• Safety and Immune Response of a Rotavirus Vaccine in HIV-infected and Uninfected Children Born to HIV-infected MothersCompletedNCT00880698Phase 2Results posted
• Uncomplicated Skin and Soft Tissue Infections Caused by Community-Associated Methicillin-Resistant Staphylococcus AureusCompletedNCT00730028Phase 2Results posted
• Short-Term vs. Long-Term Valganciclovir Therapy for Symptomatic Congenital CMV InfectionsCompletedNCT00466817Phase 3Results posted
• Development of Immune Globulin Treatment for Avian FluTerminatedNCT00383071Phase 2Results posted
• Drug Treatment Combined With Drug and Risk Reduction Counseling to Prevent of HIV Infection and Death Among Injection Drug UsersTerminatedNCT00270257Phase 3Results posted
• Anti-HIV Drugs for Treating Infants Who Acquired HIV Infection at BirthCompletedNCT00102960Phase 3Results posted
• Feasibility of Measuring Immune Resp, Activation in Foreskin/Mucosa in HIV-, Uncircumcised High-HIV-risk MSM, Lima PeruCompletedNCT02630082Not applicable
• Collection of Plasma From People Who Recovered From or Were Vaccinated to Emerging Infectious DiseasesCompletedNCT02338986
• Human Immunity Against Staphylococcus Aureus Skin InfectionCompletedNCT02262819Phase 1
• Immune Responses to Mycobacterium Tuberculosis (Mtb) in People With Latent Tuberculosis Infection With or Without Concomitant Helminth InfectionTerminatedNCT02225158
• Sildenafil for PNTM InfectionCompletedNCT01853540Phase 1/2
• Effect of Filarial Infection on Immune Responses in Latent TuberculosisCompletedNCT01547884
• Evaluating the Safety and Immune Response to Two Pneumococcal Vaccines in HIV-Infected Pregnant WomenWithdrawnNCT01443117Phase 2
• Host Factors in Invasive and Recurrent Staphylococcus Aureus InfectionTerminatedNCT00911430
• Hepatitis B and HIV Co-Infection in Patients in UgandaCompletedNCT00782158
• Influenza in People With Normal and Weakened Immune SystemsCompletedNCT00533182
• Examining Factors That May Influence Resistance to HIV-1 InfectionCompletedNCT00351442
• Changes in HIV Viral Load in Patients Undergoing Treatment for FilariasisCompletedNCT00344279
• Surveillance of Streptococcal Infections in Children in IndiaCompletedNCT00342199
• The Effect of Parasitic Worm Infections on the Immune Response to Tuberculosis BacteriaCompletedNCT00342017
• Doxycycline to Treat Mansonella Perstans Infection in Patients With and Without Lymphatic FilariasisCompletedNCT00340691Phase 2
• CMV Infection in Adolescent MalesTerminatedNCT00302029
• Acute HIV Infection Observational StudyCompletedNCT00296660
• Prevalence of HIV and Other Sexually Transmitted Infections Among Female Sex Workers and Miners in Honghe Prefecture, Yunnan Province, ChinaCompletedNCT00278499
• Bacterial Pulmonary Infection in PICUCompletedNCT00271531
• Controlling Acute or Early HIV Infection With Antiretroviral Drugs, Without a Candidate Vaccine.As Reported Previously, the Candidate Vaccie Was Not Provided by the Maufacturer as PromisedCompletedNCT00238459
• Immune Response to a Therapeutic HIV Vaccine Followed by Treatment Interruption in Patients With Acute or Recent HIV InfectionCompletedNCT00183261Phase 2
• Acute Viral Respiratory Infections in ElderlyTerminatedNCT00170495
• gB/MF59 Vaccine in Preventing Cytomegalovirus Infection in Healthy Adolescent FemalesCompletedNCT00133497Phase 2
• Safety of and Immune Response to a DNA HIV Vaccine (VRC-HIVDNA009-00-VP) in HIV Infected Individuals With Acute HIV InfectionCompletedNCT00125099Phase 1/2
• Adjuvant Cytokine Therapy to Treat Pulmonary Mycobacterium Avium Complex InfectionCompletedNCT00111397Phase 1
• Long-term Follow-up of HIV Infected Patients Identified During Early InfectionCompletedNCT00086372
• Anti-HIV Medications and Structured Treatment Interruptions for People Recently Infected With HIVWithdrawnNCT00084032Not applicable
• Daily Tenofovir DF to Prevent HIV Infection Among Sex Workers in CambodiaWithdrawnNCT00078182Phase 2/3
• BufferGel and PRO 2000/5: Vaginal Gels to Prevent HIV Infection in WomenCompletedNCT00074425Phase 2
• VRC 300: Screening of Healthy Volunteers for Clinical Trials of Investigational Vaccines to Prevent Infectious DiseasesCompletedNCT00068926
• When to Start Anti-HIV Drugs in Patients With Opportunistic InfectionsCompletedNCT00055120Phase 4
• Posaconazole to Treat Invasive Fungal InfectionsCompletedNCT00033982Phase 3
• Influenza Vaccine in HIV Infection: Immune Response and Effect on Viral LoadCompletedNCT00025922
• Intermittent vs. Continuous HAART to Treat Chronic HIV InfectionCompletedNCT00025909Phase 3
• A Randomized, Double-Blinded, Placebo-Controlled, Phase II Inhaled Interferon Gamma-1b and Antimycobacterials to Treat Pulmonary Mycobacterium Avium Complex InfectionsCompletedNCT00021567Phase 2
• Nerve Damage in Patients With HIV Infection Who Have Been Treated With Anti-HIV DrugsCompletedNCT00017771
• Combination Treatment With and Without Protease Inhibitors for Women Who Begin Therapy for HIV Infection During PregnancyCompletedNCT00017719Phase 3
• Pneumococcal Vaccine and Routine Pediatric Immunizations in HIV-Infected Children Receiving Anti-HIV DrugsCompletedNCT00013871Not applicable
• Comparison of Three Different Initial Treatments Without Protease Inhibitors for HIV InfectionCompletedNCT00013520Phase 3
• Vaccinia Immune Globulin in Treating or Preventing Vaccinal InfectionWithdrawnNCT00006630Phase 1
• Effectiveness of Anti-HIV Drugs in Patients Who Have Not Received Previous Anti-HIV Drugs During Different Stages of HIV InfectionCompletedNCT00006443Not applicable
• A Test of Behavioral Intervention for Women at High Risk for HIV InfectionCompletedNCT00006440
• Safety and Effectiveness of an Anti-HIV Drug Combination With and Without Hydroxyurea in Patients With Early HIV InfectionWithdrawnNCT00006339Phase 2
• Studies of HIV-1 Infection in Newly Infected Individuals in Southern AfricaCompletedNCT00006298
• A Study to Evaluate the Use of a Protease Inhibitor and of Interleukin-2 (IL-2) in the Treatment of Early HIV InfectionCompletedNCT00006154Phase 3
• Preventing Cytomegalovirus (CMV) Organ Damage With Valganciclovir in People With HIVCompletedNCT00006145Phase 3
• A Comparison of HIV-Infected Patients With and Without Opportunistic (AIDS-Related) InfectionCompletedNCT00005572
• Observing Patients With Early HIV InfectionCompletedNCT00005020
• Comparison of Two Test Methods-NASBA and Antigenemia-for Detecting Cytomegalovirus InfectionCompletedNCT00001976
• Interleukin-12 in the Treatment of Severe Nontuberculous Mycobacterial InfectionsCompletedNCT00001911Phase 1
• Prevention of RSV Infections in Bone Marrow Transplant RecipientsCompletedNCT00001903Phase 4
• Subcutaneously Administered Interleukin-12 Therapy in HIV-Infected Patients With Disseminated Mycobacterium Avium Complex InfectionCompletedNCT00001763Phase 1
• Use of Combined Antiretroviral Therapy to Determine Sites of Persistent HIV InfectionCompletedNCT00001644Phase 1
• Monitoring Patients for Developing Communicable and Opportunistic Infections and for Responding to TherapyCompletedNCT00001477
• Gene Therapy for Chronic Granulomatous Diseases - Long-term Follow-upCompletedNCT00001476Phase 1
• Treatment of Non-Tuberculous Mycobacterial Infections With Interferon GammaCompletedNCT00001318Phase 2
• Study of Patients With Strongyloides Stercoralis InfectionCompletedNCT00001245
• Parasitic Infections of the Gastrointestinal TractTerminatedNCT00001162
• A Study to Evaluate the Effects of Anti-HIV Drugs in HIV-Positive Patients Who Also Have Hepatitis C InfectionCompletedNCT00001117
• The Effect of Acyclovir Treatment of the Herpes Simplex Virus (HSV) Infection on HIV Levels in the BloodCompletedNCT00001115Not applicable
• A Phase III Study to Evaluate the Safety and Efficacy of Ganciclovir (Dihydroxypropoxymethyl Guanine [DHPG]) Treatment of Symptomatic Central Nervous System (CNS) Congenital Cytomegalovirus (CMV) Infections.CompletedNCT00001100Phase 3
• Outcomes of Anti-HIV Therapy During Early HIV InfectionCompletedNCT00001093
• A Study of HIV and Cytomegalovirus (CMV) in HIV-Infected PatientsCompletedNCT00001089
• The Safety and Effectiveness of Adefovir Dipivoxil in the Treatment of HIV-Infected PatientsCompletedNCT00001082Phase 3
• A Study on the Rate of Opportunistic (AIDS-Related) Infections Among HIV-Positive Children Who Have Stopped Taking Their OI Preventive MedicationsCompletedNCT00001078Not applicable
• A Comparison of Three Drug Combinations Containing Clarithromycin in the Treatment of Mycobacterium Avium Complex (MAC) Disease in Patients With AIDSCompletedNCT00001058Phase 2
• The Safety and Effectiveness of Valacyclovir HCl in the Treatment of Herpes Simplex or Varicella/Zoster Infections in HIV-1 Infected ChildrenWithdrawnNCT00001054Phase 1
• Study of Four Different Treatment Approaches for Patients Who Have Mycobacterium Avium Complex Disease (MAC) Plus AIDSCompletedNCT00001047Phase 3
• Evaluation of Treatment for Mycobacterium Avium Complex (MAC) Infection in HIV-Infected PatientsCompletedNCT00001039Phase 2
• A Study of Valacyclovir Hydrochloride in the Prevention of Life-Threatening Cytomegalovirus Disease in HIV-Infected PatientsCompletedNCT00001038Phase 3
• The Safety and Effectiveness of a Two-Drug Combination in the Treatment of Patients With Hepatitis C Plus Advanced HIV InfectionsCompletedNCT00001035Phase 1
• The Safety and Effectiveness of Clarithromycin and Rifabutin Used Alone or in Combination to Prevent Mycobacterium Avium Complex (MAC) or Disseminated MAC Disease in HIV-Infected PatientsCompletedNCT00001030Phase 3