Dentsply Sirona clinical trials
The registry lists 71 studies whose lead sponsor is Dentsply Sirona or one of 4 companies grouped under it. 4 are recruiting or about to start. Per ClinicalTrials.gov, last updated Oct 6, 2026.
Our grouping of 5 registry names, not the registry’s. See them and correct one ↓
- 71studies on the registry
- 4open to participants now
Get an email when these change. Save the Dentsply Sirona studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
See an example email
Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
One email a week for all your saved searches. Stop any time.
What it is testing
The drugs Dentsply Sirona’s studies test, most studies first; none is open now — 2 drugs with a page of their own. Each count opens the studies in search.
Studies, none open
All 71 at a glance
Where each study is in its life, its phase and its countries. Each count opens them in search.
Over the years
- 07
- 08
- 09
- 10
- 1011
- 12
- 13
- 14
- 15
- 16
- 17
- 18
- 19
- 20
- 21
- 22
- 23
- 24
- 25
- 326
By the year each study started; 9 started before 2007. 2026 so far in the lighter column.
Registry sponsor names on this page
Our grouping. This page groups the registry's lead sponsor names by company — our grouping, not the registry's. It can be wrong or incomplete: an acquired company whose name never mentions its owner may be missing. Use “Something wrong?” under any name below to correct it.
Tell us about a missing company
Each name exactly as ClinicalTrials.gov lists it, and how it relates to Dentsply Sirona.
- Dentsply Sirona Implants and Consumables36 studies →Division
Something wrong?
- Wellspect HealthCare23 studies →Acquired — became part of Dentsply Sirona, Aug 31, 2011 · source ↗
Something wrong?
- Dentsply International10 studiesSame company
Something wrong?
- Dentsply Implants Manufacturing GmbH1 study →Acquired
Something wrong?
- Sirona Dental Systems GmbH1 study →Acquired — became part of Dentsply Sirona, Feb 29, 2016 · source ↗
Something wrong?
Focus areas
Conditions Dentsply Sirona leads ten or more studies in, by study count. A broader condition is left out when almost all its studies are already in a narrower one listed here.
Studies
Recruiting first, then most recently updated. Showing 50 of 71. Browse all 71 →
- Clinical Outcomes of 3D Printed and Milled Complete DenturesRecruitingNCT07586774Not applicable
Sponsor listed in the registry: Dentsply Sirona Implants and Consumables
- Clinical Performance of AH Plus Jet® Root Canal Sealers in Single-cone ProtocolsRecruitingNCT07642284Not applicable
Sponsor listed in the registry: Dentsply Sirona Implants and Consumables
- A Prospective Multicenter Clinical Investigation Evaluating the Accuracy of the Trimline Design When Treated With SureSmile® Aligners.RecruitingNCT07290790Not applicable
Sponsor listed in the registry: Dentsply Sirona Implants and Consumables
- Comparing Transanal Irrigation With Navina Smart vs. Standard Bowel Care in Patients With Multiple SclerosisRecruitingNCT04707976Not applicable
Sponsor listed in the registry: Wellspect HealthCare · First submitted after Wellspect HealthCare became part of Dentsply Sirona
- Multicenter Study to Evaluate the Clinical Outcome of PrimeTaper EV Implant in Single Tooth RestorationsActive, not recruitingNCT05315414Not applicable
Sponsor listed in the registry: Dentsply Sirona Implants and Consumables
- A Clinical Study on Acuris™ - Conometric Concept for Single Tooth RestorationActive, not recruitingNCT04063878Not applicable
Sponsor listed in the registry: Dentsply Sirona Implants and Consumables
- Clinical Evaluation of Implants Restored With Advanced Lithium Disilicate Screw-retained CrownsActive, not recruitingNCT05752539
Sponsor listed in the registry: Dentsply Sirona Implants and Consumables
- Clinical Study of a 3D Shaded Zirconia for Chairside CAD/CAM RestorationsActive, not recruitingNCT06713577
Sponsor listed in the registry: Dentsply Sirona Implants and Consumables
- Multicenter Study to Evaluate the Clinical Outcome of the OmniTaper EV Implant in Single Tooth RestorationsActive, not recruitingNCT05355792Not applicable
Sponsor listed in the registry: Dentsply Sirona Implants and Consumables
- An Evaluation of Navina Mini, a New Trans-anal Irrigation (TAI) Device in Children and AdolescentsCompletedNCT06385249Not applicable
Sponsor listed in the registry: Wellspect HealthCare · First submitted after Wellspect HealthCare became part of Dentsply Sirona
- A Study to Compare Nighttime Aligners to Daytime AlignersTerminatedNCT06539676Not applicable
Sponsor listed in the registry: Dentsply Sirona Implants and Consumables
- En Evaluation of Navina Mini, a New Low-volume Transanal Irrigation Device.CompletedNCT06377280Not applicable
Sponsor listed in the registry: Wellspect HealthCare · First submitted after Wellspect HealthCare became part of Dentsply Sirona
- Evaluation of Self-adhesive Hybrid Resin Composite Compared to a Traditional Composite Resin in Restorations of NCCLsTerminatedNCT05751382Not applicable
Sponsor listed in the registry: Dentsply Sirona Implants and Consumables
- A Study Evaluating OsseoSpeed TX Using Different Drilling Protocols With Immediate LoadingCompletedNCT01340170Not applicable
Sponsor listed in the registry: Dentsply Sirona Implants and Consumables
- Exploratory Investigation on a Novel CatheterCompletedNCT05644912Not applicable
Sponsor listed in the registry: Wellspect HealthCare · First submitted after Wellspect HealthCare became part of Dentsply Sirona
- Retrospective Evaluation of Clinical Performance of the Astra Tech Implant System EV When Used in Everyday PracticeCompletedNCT03845738
Sponsor listed in the registry: Dentsply Sirona Implants and Consumables
- Implant-fixed Restorations With ANKYLOS 6.6 mm Implants in the Edentulous Maxilla - A 5-year Follow-up StudyCompletedNCT02656823Not applicable
Sponsor listed in the registry: Dentsply Sirona Implants and Consumables
- Patient Reported Outcome Study on Long Term LoFric UsersStatus unknownNCT05359198
Sponsor listed in the registry: Wellspect HealthCare · First submitted after Wellspect HealthCare became part of Dentsply Sirona
- User Satisfaction When Catheterizing With Hydrophilic Urinary Catheters From a More Sustainable Manufacturing Process.TerminatedNCT04703413Not applicable
Sponsor listed in the registry: Wellspect HealthCare · First submitted after Wellspect HealthCare became part of Dentsply Sirona
- Evaluation of a New Female Urinary Intermittent CatheterCompletedNCT04304599Not applicable
Sponsor listed in the registry: Wellspect HealthCare · First submitted after Wellspect HealthCare became part of Dentsply Sirona
- Short Implants - An Alternative to Bone Grafting?CompletedNCT01030523Not applicable
Sponsor listed in the registry: Dentsply Sirona Implants and Consumables
- Study of Bone Preservation When OsseoSpeed™ Implants Are Placed Immediately Following Tooth ExtractionCompletedNCT00711282Not applicable
Sponsor listed in the registry: Dentsply Sirona Implants and Consumables
- Evaluation of a Novel Electronic Transanal Irrigation System - Navina™ SmartCompletedNCT02709395Not applicable
Sponsor listed in the registry: Wellspect HealthCare · First submitted after Wellspect HealthCare became part of Dentsply Sirona
- Study to Evaluate Bone and Gum Dimension Changes Around Dental Implants Placed in Different Positions in Bone.CompletedNCT01759537Not applicable
Sponsor listed in the registry: Dentsply International
- Comparative Study of Experimental Dental Adhesive With and Without Phosphoric Acid PretreatmentCompletedNCT02071953Not applicable
Sponsor listed in the registry: Dentsply International
- Study to Evaluate an Implant With a Sloped Top in Patients With a Sloped Jaw BoneCompletedNCT00807456Not applicable
Sponsor listed in the registry: Dentsply Sirona Implants and Consumables
- XiVE® CAD/CAM Bridges (Abutment-supported/ Implant-supported)CompletedNCT01522365Not applicable
Sponsor listed in the registry: Dentsply Implants Manufacturing GmbH · Dentsply Implants Manufacturing GmbH — acquired company within the Dentsply Sirona group
- A Descriptive, Prospective Clinical Study to Evaluate Full Dentures Fabricated by Additive ManufacturingWithdrawnNCT03997604
Sponsor listed in the registry: Dentsply International
- Reduction of Bacteriuria in Subjects Practicing Intermittent CatheterizationCompletedNCT01143116Not applicable
Sponsor listed in the registry: Wellspect HealthCare · First submitted before Wellspect HealthCare became part of Dentsply Sirona
- Evaluation of a New Catheter Material for Intermittent CatheterizationCompletedNCT01295281Not applicable
Sponsor listed in the registry: Wellspect HealthCare · First submitted before Wellspect HealthCare became part of Dentsply Sirona
- Efficacy of Clean Intermittent Catheterization (CIC) in Multiple Sclerosis (MS) Patients With Bladder DysfunctionTerminatedNCT00913510Not applicable
Sponsor listed in the registry: Wellspect HealthCare · First submitted before Wellspect HealthCare became part of Dentsply Sirona
- A Clinical Study to Investigate if Transfusion of Patients Own Shed Blood Improves the Immunological Status in Comparison to Transfusion of Donor Blood ("Bank Blood")CompletedNCT00839241Not applicable
Sponsor listed in the registry: Wellspect HealthCare · First submitted before Wellspect HealthCare became part of Dentsply Sirona
- The Value of Multiple Urine Flow Rate Measurements in Male Benign Prostatic Hyperplasia (BPH) SubjectsCompletedNCT00710749Not applicable
Sponsor listed in the registry: Wellspect HealthCare · First submitted before Wellspect HealthCare became part of Dentsply Sirona
- Comparison Between Return and Wastage of Your Own Blood, Collected During Spinal Surgery, for Verification of Safety When Returning BloodCompletedNCT01251042Not applicable
Sponsor listed in the registry: Wellspect HealthCare · First submitted before Wellspect HealthCare became part of Dentsply Sirona
- A Randomized, Fully-blinded Parallel Groups Study of Catheter Materials Used for Clean Intermittent CatheterisationCompletedNCT00753298Not applicable
Sponsor listed in the registry: Wellspect HealthCare · First submitted before Wellspect HealthCare became part of Dentsply Sirona
- A Comparison of Two Urinary Catheters of Different Lengths for Female Use, in Intermittent CatheterizationCompletedNCT00799981Not applicable
Sponsor listed in the registry: Wellspect HealthCare · First submitted before Wellspect HealthCare became part of Dentsply Sirona
- A Study Evaluating a Urinary Catheter With Different Activation Times for the Wetting Solution, in Healthy Male Volunteers.CompletedNCT00748033Not applicable
Sponsor listed in the registry: Wellspect HealthCare · First submitted before Wellspect HealthCare became part of Dentsply Sirona
- An Observational Clinical Case Series Study to Assess Fit and Quality of Full Dentures Fabricated by AMTerminatedNCT04023006
Sponsor listed in the registry: Dentsply International
- Study Where Healthy Volunteers Evaluate LoFric CathetersCompletedNCT00802750Not applicable
Sponsor listed in the registry: Wellspect HealthCare · First submitted before Wellspect HealthCare became part of Dentsply Sirona
- Pediatric Study to Access Pharmacokinetics and Safety of Oraqix GelCompletedNCT01591616Phase 4
Sponsor listed in the registry: Dentsply International
- Study Comparing OsseoSpeed™ Implants of Two Different Lengths in the Upper and Lower Posterior JawCompletedNCT00545818Not applicable
Sponsor listed in the registry: Dentsply Sirona Implants and Consumables
- Study Comparing Appearance and Function of Three Different Dental Implant Designs When Placed in Front Region of Upper JawCompletedNCT00820235Not applicable
Sponsor listed in the registry: Dentsply Sirona Implants and Consumables
- Study on OsseoSpeed™ TX Implants in the Upper Jaw in a Chinese PopulationCompletedNCT01389245Not applicable
Sponsor listed in the registry: Dentsply Sirona Implants and Consumables
- Multicenter Retrospective Study Evaluating ATLANTIS™ Abutment Teeth Connected to ImplantsCompletedNCT02496091
Sponsor listed in the registry: Dentsply Sirona Implants and Consumables
- Multicenter Study Comparing OsseoSpeed TX With OsseoSpeed EV.CompletedNCT01528215Not applicable
Sponsor listed in the registry: Dentsply Sirona Implants and Consumables
- An Open, Qualitative, Prospective, Multicenter Trial of a Novel Transanal Irrigation System in Spinal Cord Injured Patients.CompletedNCT02979808Not applicable
Sponsor listed in the registry: Dentsply International
- Study Evaluating ASTRA TECH Implant System, OsseoSpeed™ Implants in the Upper Jaw in Women With OsteoporosisCompletedNCT00745121Not applicable
Sponsor listed in the registry: Dentsply Sirona Implants and Consumables
- Study Evaluating OsseoSpeed™ Narrow Implant in the Upper and Lower Anterior JawCompletedNCT00646113Not applicable
Sponsor listed in the registry: Dentsply Sirona Implants and Consumables
- Study on OsseoSpeed™ TX Narrow Implants in the Lower Jaw in a Chinese PopulationCompletedNCT01473355Not applicable
Sponsor listed in the registry: Dentsply Sirona Implants and Consumables
- Study on OsseoSpeed™ TX Narrow Implants in the Upper Jaw in a Chinese PopulationCompletedNCT01389258Not applicable
Sponsor listed in the registry: Dentsply Sirona Implants and Consumables