Supplement
Trichlorosucrose clinical trials
Also written Sucralose.
- studies test it
- 17
- open now
- 6
- in phase 3
- 0
- first study started
- 2011
Keep track of what changes. Save the trichlorosucrose studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Other names
Combined with it in one product
Studies by the year they started
17 studies that test it; most in 2026 (4)
| Year | Studies |
|---|---|
| 2011 | 1 |
| 2014 | 2 |
| 2015 | 2 |
| 2016 | 2 |
| 2017 | 1 |
| 2019 | 1 |
| 2021 | 1 |
| 2022 | 1 |
| 2025 | 2 |
| 2026 | 4 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 1
- No phase
- 16
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 0 · Other 17
Yale University (4) · University Hospital, Basel, Switzerland (2) · Weizmann Institute of Science (1) · Hospital General de México Dr. Eduardo Liceaga (1) · University of Illinois at Urbana-Champaign (1) · Ramathibodi Hospital (1) · Toronto Metropolitan University (1) · Tufts University (1)
Often tested with
Tested in the same studies.
Sucrose (6) · Erythritol (3) · Saccharin (3) · Glucose (2) · Maltodextrin (2) · Aspartame (1) · Water (1) · Nicotine (1)
Studies
Open first, then newest update. How each study uses trichlorosucrose is read from its arms, and is right about nine times in ten.
Testing it · 17
- Glycemic Impact of NNS Via the Gut MicrobiomeEnrolling by invitationNot applicableTufts UniversityNCT07868432Written as Sucralose
- Impact of Sweeteners on the Addictive Threshold of NicotineNot yet recruitingPhase 1Yale UniversityNCT07771725Written as sucralose
- Effects of Sweetener Consumption on Risk Factors for Heart Disease in Prediabetic SubjectsNot yet recruitingNot applicableCharite University, Berlin, GermanyNCT07377097Written as Sucralose
- Short-Term Effects of Sucralose and Saccharin on Blood Sugar and Gut Microbiota in Type 2 DiabetesNot yet recruitingNot applicableNational University of MalaysiaNCT07124585Written as Sucralose
- the Effect of Monk Fruit and Splenda on Salivary Ph and Streptococcus Mutans Count in Vivo StudyNot yet recruitingNot applicableAl-Mustansiriyah UniversityNCT06921434Written as Splenda (sucralose) sweetener mouth rinse
- Sucralose as a Way to Enhance Regulatory T CellsNot yet recruitingNot applicableCaroline LamarcheNCT06997133Written as sucralose
- Assessment of Reward Responses to Erythritol Using Flavor Preference LearningCompletedNot applicableUniversity Hospital, Basel, SwitzerlandNCT05279183Written as Sucralose
- Effects of Oral Pre-loads on Subsequent Energy IntakeCompletedNot applicableUniversity Hospital, Basel, SwitzerlandNCT04713137Written as Sucralose
- Microbiome and Non-caloric Sweeteners in HumansCompletedNot applicableWeizmann Institute of ScienceNCT03708939Written as Sucralose
- Effects of Artificial Sweeteners on Glucose Metabolism in Patients With Type 2 DiabetesStatus unknownNot applicableRenJi HospitalNCT04185662Written as sucralose
- The Effect of Artificial Sweeteners (AFS) on Sweetness Sensitivity, Preference and Brain Response in AdultsCompletedNot applicableYale UniversityNCT02335021Written as Sucralose
- Serum Insulin Response After Acute and Chronic Sucralose Ingestion in Healthy Volunteers With Variable Body Mass IndexCompletedNot applicableHospital General de México Dr. Eduardo LiceagaNCT03703141Written as sucralose 48 mg (splenda)/day for ten weeks
- The Effect of Artificial Sweeteners (AFS) on Sweetness Sensitivity, Preference and Brain Response in AdolescentsTerminatedNot applicableYale UniversityNCT02499705Written as Sucralose
- Metabolic Effects of Non-nutritive SweetenersCompletedNot applicableUniversity of Illinois at Urbana-ChampaignNCT02413424Written as Sucralose
- Sucralose Effects on Glucose Metabolism and Gut MicrobiotaCompletedNot applicableRamathibodi HospitalNCT02650947Written as Sucralose
- The Effect of Artificial Sweeteners (AFS) on Sweetness Sensitivity and Preference - PilotCompletedNot applicableYale UniversityNCT02335008Written as Sucralose
- Sugars-containing Beverage and Food Intake in ChildrenCompletedNot applicableToronto Metropolitan UniversityNCT01717716Written as water with Sucralose
Codes
What other systems call trichlorosucrose · ClinicalTrials.gg INT002831
- MeSH (NLM) C026285trichlorosucroseConfirmed ClinicalTrials.gov, NLM
- UNII (FDA) 96K6UQ3ZD4SUCRALOSEConfirmed FDA, NLM
- RxNorm 1439115One source FDA
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C026285 | trichlorosucrose | Confirmed ClinicalTrials.gov, NLM |
| UNII (FDA) | 96K6UQ3ZD4 | SUCRALOSE | Confirmed FDA, NLM |
| RxNorm | 1439115 | — | One source FDA |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.