Topotecan: all 270 studies that test it
Page 2 of 3. Open to participants first (17), then studies with results posted, then the rest; newest registration first within each.
- Tivantinib and Topotecan Hydrochloride in Treating Patients With Advanced or Metastatic Solid TumorsCompletedNCT01654965Phase 1
- Belotecan Versus Topotecan for Recurrent Ovarian Cancer: A Randomized, Open-label, Parallel-group Phase IIb TrialCompletedNCT01630018Phase 2
- Trial of pasireotideLAR and Topotecan in Relapsed or Refractory Small Cell Lung CancerStatus unknownNCT01417806Phase 2
- Tandem High Dose Chemotherapy and Autologous Stem Cell Rescue for High Risk Pediatric Brain TumorsStatus unknownNCT01342237Phase 2
- Trial of High Dose Topotecan With Carboplatin in Patients With Relapsed Ovarian CarcinomaTerminatedNCT01177501Phase 1
- TMC (Topotecan, Cyclophosphamide and Melphalan) for Multiple MyelomaCompletedNCT01039025Phase 2
- Pilot Study of Topotecan/Vincristine With Subconjunctival Carboplatin for Patients With Bilateral RetinoblastomaWithdrawnNCT00980551Not applicable
- Iodobenzylguanidine Meta-I131 and Topotecan in Young Patients With Refractory or Relapsed Metastatic NeuroblastomaCompletedNCT00960739Phase 2
- Studies of Temozolomide in Combination With Topotecan in Refractory and Relapsed Paediatric Solid TumoursCompletedNCT00918320Phase 2
- Efficacy of Topotecan and Lapatinib in Early Recurrent Ovarian or Peritoneal CancerTerminatedNCT00888810Phase 2
- Safety of MP470 in Combination With Standard-of-Care Chemotherapy Regimens to Treat Solid TumorsCompletedNCT00881166Phase 1
- Topotecan Hydrochloride and Doxorubicin Hydrochloride in Treating Relapsed or Refractory Small Cell Lung CancerCompletedNCT00856037Phase 1
- Topotecan in Treating Patients With Gynecologic Cancer That Cannot Be Removed by SurgeryCompletedNCT00842452Phase 1
- Topotecan and Cisplatin Versus Etoposide and Carboplatin in 1st Line Treatment of Patients With Small Cell Lung Cancer and Extensive Disease (SCLC-ED)TerminatedNCT00812266Phase 3
- Carboplatin and Topotecan in Treating Patients With Relapsed or Metastatic Cervical CancerCompletedNCT00807079Phase 1/2
- Study of Temsirolimus, Topotecan, and BortezomibCompletedNCT00770731Phase 1
- Open-label Study of Topotecan and Pazopanib in Advanced Solid TumorsCompletedNCT00732420Phase 1
- Study of the Weekly Oral RAD001 in Combination With Oral Topotecan in Patients With Advanced or Recurrent Endometrial CancersCompletedNCT00703807Phase 1
- Study of Oral Vorinostat in Combination With Topotecan in Patients With Chemosensitive Recurrent SCLCTerminatedNCT00697476Phase 1/2
- Phase 1 Intrathecal Topotecan for Neoplastic MeningitisCompletedNCT00674674Phase 1
- Topotecan, High-Dose Cyclophosphamide, Carboplatin, and an Autologous Peripheral Blood Cell Transplant in Treating Patients With Recurrent Ovarian Cancer or Primary Peritoneal CancerCompletedNCT00652691Phase 1
- Busulfan, Melphalan, Topotecan Hydrochloride, and a Stem Cell Transplant in Treating Patients With Newly Diagnosed or Relapsed Solid TumorCompletedNCT00638898Phase 1
- Ph I Oral Topotecan and Temozolomide for Patients With Malignant GliomasCompletedNCT00610571Phase 1
- Veliparib and Topotecan With or Without Carboplatin in Treating Patients With Relapsed or Refractory Acute Leukemia, High-Risk Myelodysplasia, or Aggressive Myeloproliferative DisordersCompletedNCT00588991Phase 1
- Safety Study of ABT-888 Plus Topotecan Hydrochloride to Treat Patients With Solid Tumors and LymphomasCompletedNCT00553189Phase 1
- Combination Chemotherapy and Autologous Peripheral Stem Cell Transplant in Treating Patients With Stage III, Stage IV, or Recurrent Ovarian Epithelial Cancer, Primary Peritoneal Cancer, or Fallopian Tube CancerCompletedNCT00550784Phase 1
- Bortezomib and Topotecan Hydrochloride in Treating Patients With Advanced Solid TumorsCompletedNCT00541359Phase 1
- Tamoxifen, Carboplatin, and Topotecan in Treating Patients With CNS Metastases or Recurrent Brain or Spinal Cord TumorsCompletedNCT00541138Phase 2
- A Phase I Study of CCI-779 (Temsirolimus) in Combination With Topotecan in Patients With Gynecologic MalignanciesCompletedNCT00523432Phase 1
- Study to Assess the Safety and Tolerability of a PARP Inhibitor in Combination With TopotecanCompletedNCT00516438Phase 1
- Topotecan, Ifosfamide and Carboplatin in Children and Young Adults With Solid TumorsCompletedNCT00502892Phase 1
- Topotecan for Irinotecan-Refractory SCLCStatus unknownNCT00502762Phase 2
- Fludarabine, Cytarabine, Topotecan in Treating Patients With Relapsed or Refractory Acute Myeloid LeukemiaCompletedNCT00488709Phase 4
- A Phase I Topotecan Study in Subjects With Cancer and Impaired Renal FunctionCompletedNCT00483860Phase 1
- Phase I Study of Weekly Topotecan in Combination With Sorafenib in Treatment of Relapsed Small Cell Lung CancerCompletedNCT00466232Phase 1
- Combination Chemotherapy in Treating Young Patients With Relapsed or Refractory Acute LeukemiaCompletedNCT00462787Phase 1
- Phase I Trial of Periocular Topotecan in RetinoblastomaCompletedNCT00460876Phase 1
- Hycamtin Plus Carboplatin Versus Established Regimens for the Treatment of Ovarian Cancer RelapseCompletedNCT00437307Phase 3
- Topotecan in Combination With Gemcitabine in Patients With Platinum-resistant Ovarian CarcinomaCompletedNCT00429559Phase 1/2
- A Study Evaluating BSI-201 in Combination With Chemotherapeutic Regimens in Subjects With Advanced Solid TumorsCompletedNCT00422682Phase 1
- Temozolomide in Association With Topotecan in Refractory or Relapsed Malignant Tumors in Children and AdolescentsCompletedNCT00412503Phase 1
- Study of AT-101 in Combination With Topotecan in Relapsed/Refractory Small Cell Lung CancerCompletedNCT00397293Phase 1/2
- Topotecan, Vincristine, and Doxorubicin in Treating Young Patients With Refractory Stage 4 NeuroblastomaStatus unknownNCT00392340Phase 2
- High-Dose Iodine I 131 Metaiodobenzylguanidine, Topotecan, and Peripheral Stem Cell Transplant in Treating Young Patients With Relapsed Stage 4 Neuroblastoma or Primary Resistant High-Risk NeuroblastomaWithdrawnNCT00389766Phase 2
- Bortezomib and Topotecan in Treating Patients With Advanced Solid TumorsCompletedNCT00388089Phase 1
- Topotecan Pharmacokinetic Characterization StudyCompletedNCT00361803Phase 1
- Combination Chemotherapy With or Without Topotecan in Treating Patients With Newly Diagnosed Localized Ewing's SarcomaWithdrawnNCT00334867Phase 3
- Efficacy Study of Weekly Topotecan With Cisplatin in Advanced Stage or Recurrent Cervical CancerTerminatedNCT00322920Phase 1
- Concurrent Radiotherapy With Weekly Topotecan for Primary Treatment of Inoperable Localized Non-small Cell Lung CancerCompletedNCT00322751Phase 1
- Study of Adjuvant Topotecan and Cisplatin With Concurrent Radiation Therapy for Advanced Cervical CancerCompletedNCT00320983Phase 1
- Topotecan Plus Cisplatin Versus Etoposide Plus Cisplatin In 1st Line Extensive Disease Small Cell Lung CancerCompletedNCT00320359Phase 3
- Topotecan in Combination With Pemetrexed in Patients With Advanced MalignanciesCompletedNCT00315861Phase 1
- Weekly Topotecan With Docetaxel in Recurrent Small Cell Lung CancerTerminatedNCT00315211Phase 2
- Phase I Study of GW572016 With Topotecan to Treat Advanced Solid MalignanciesCompletedNCT00295243Phase 1
- Higher Dose Weekly Topotecan In The Treatment Of Patients With Extensive Stage Small-Cell Lung CancerCompletedNCT00294190Phase 2
- Topotecan and Vinorelbine in Treating Patients With Recurrent Lung CancerCompletedNCT00287963Phase 1
- Topotecan, Cisplatin, and Radiation Therapy in Treating Patients With Advanced Cervical CancerCompletedNCT00287911Phase 1
- Topotecan in Treating Patients With Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cavity CancerTerminatedNCT00287859Phase 1
- Paclitaxel, Topotecan, and Cisplatin in Treating Patients With Advanced, Persistent, or Recurrent Cervical CancerCompletedNCT00276796Phase 2
- Active Symptom Control Alone Or In Combination With Oral Topotecan In Patients With Relapsed Resistant Small Cell Lung CancerCompletedNCT00276276Phase 3
- A Study To Determine If Two Different Versions Of Topotecan Have The Same Potency In Patients With Advanced Solid TumorsCompletedNCT00259935Phase 1
- Weekly IV Topotecan and Cisplatin With Radiation in Cervical CarcinomaCompletedNCT00257816Phase 2
- Doxil Topotecan Doublet Cancer StudyCompletedNCT00252889Phase 1
- Clinical Benefit of Topoisomerase DownregulationCompletedNCT00250094Phase 1
- Efficacy Study of Weekly Taxotere and Topotecan for Recurrent Gynecologic (GYN) CancersCompletedNCT00231855Phase 2
- Gemcitabine and Topotecan in Treating Patients With Recurrent or Persistent Ovarian, Fallopian Tube, or Primary Peritoneal Cavity CancerCompletedNCT00217555Phase 2
- A Phase I Study of Oral Topotecan as a Radiosensitizing Agent in Patients With Rectal CarcinomaCompletedNCT00215956Phase 1
- Weekly Topotecan Therapy in Patients With Ovarian CancerTerminatedNCT00194935Phase 2
- Weekly Topotecan in Combination With Carboplatin in Two Different Schedules for Refractory and/or Advanced Solid TumorsCompletedNCT00193583Phase 1
- Topotecan in Combination With Docetaxel in Refractory and/or Advanced Solid TumorsCompletedNCT00193570Phase 1
- Weekly Topotecan in the First-line Treatment of Elderly Patients With Small Cell Lung CancerCompletedNCT00193401Phase 2
- Weekly Topotecan in the Second-Line Treatment of Small Cell Lung CancerCompletedNCT00193388Phase 2
- Topotecan Plus Paclitaxel and Carboplatin in the Initial Treatment of Advanced Ovarian and Primary Peritoneal CarcinomaCompletedNCT00193297Phase 2
- Oral Topotecan Versus Docetaxel in Second-Line Treatment of Non-Small Cell Lung CancerCompletedNCT00193245Phase 2
- Weekly Topotecan in Patients Treated for Metastatic Colorectal CancerCompletedNCT00193167Phase 2
- Taxol® in Monotherapy or in Combination With Topotecan or Carboplatin in Patients With Epithelial Ovarian Cancer in Early RelapseCompletedNCT00189566Phase 2
- A Study of Children With Refractory or Relapsed ALLCompletedNCT00187083Phase 3
- Therapy for Children With Advanced Stage High Risk NeuroblastomaCompletedNCT00186849Phase 2
- Study of Lenalidomide With Topotecan In Subjects With Advanced Ovarian and Primary Peritoneal CarcinomaCompletedNCT00179712Phase 1/2
- Topotecan Weekly Versus Topotecan Day 1-5 in Patient With Platin-resistant Ovarian CancerCompletedNCT00170677Phase 2
- Oral Topotecan As A Radiosensitizing Agent In Rectal CancerTerminatedNCT00158886Phase 1
- A Pilot Trial of Oral Topotecan for the Treatment of Refractory Advanced Solid Neoplasms Expressing HIF-1aCompletedNCT00117013Phase 1
- Topotecan in Treating Young Patients With Neoplastic Meningitis Due to Leukemia, Lymphoma, or Solid TumorsTerminatedNCT00112619Phase 1
- Temozolomide and Topotecan in Treating Patients With Primary CNS LymphomaWithdrawnNCT00109798Not applicable
- Topotecan, G-CSF, and Radiation Therapy in Treating Young Patients With Newly Diagnosed Brain Stem GliomaTerminatedNCT00107471Phase 1/2
- Paclitaxel, Carboplatin, and Topotecan in Patients With Ovarian CancerCompletedNCT00102375Phase 3
- Use of Topotecan in Patients With Refractory Acute LeukemiaCompletedNCT00100477Phase 2
- Topotecan in Treating Patients With Recurrent Extensive-Stage Small Cell Lung CancerTerminatedNCT00087048Phase 2
- Paclitaxel, Topotecan, and Estramustine in Treating Patients With Metastatic Hormone-Refractory Prostate CancerWithdrawnNCT00084565Phase 2
- UCN-01 and Topotecan in Treating Patients With Recurrent, Persistent, or Progressive Advanced Ovarian Epithelial, Primary Peritoneal, or Fallopian Tube CancerCompletedNCT00072267Phase 2
- Induction Chemotherapy Using Cyclophosphamide and Topotecan in Treating Patients Who Are Undergoing Autologous Peripheral Stem Cell Transplantation for Newly Diagnosed or Progressive NeuroblastomaCompletedNCT00070200Phase 1
- A Dose Finding Phase I Trial of the Combination of Topotecan and PS-341, a Novel Proteasome Inhibitor, in Advanced MalignanciesCompletedNCT00068484Phase 1
- Second-line Intravenous Treatment For Recurrent Platinum-Sensitive Ovarian, Fallopian, Or Peritoneal CancerCompletedNCT00061308Phase 2
- Topotecan in Treating Patients With Advanced Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal CancerCompletedNCT00055614Phase 1
- Fludarabine/Carboplatin/Topotecan w/Thalidomide for Relapsed/Refractory AML, CML and MDSCompletedNCT00053287Phase 2
- Oral Topotecan Versus Intravenous Docetaxel In Pretreated, Advanced Non-Small Cell Lung CancerCompletedNCT00049998Phase 3
- A Bioequivalence Study of Two Oral Formulations of Topotecan in Patients With Advanced Solid TumorsCompletedNCT00046111Phase 1
- UCN-01 and Topotecan in Treating Patients With Recurrent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cavity CancerCompletedNCT00045175Phase 1
- Extensive Small Cell Lung Cancer Treatment Using An Investigational Drug Plus Chemotherapy In Chemotherapy-Naive AdultsCompletedNCT00043927Phase 3
- The Study Of An Oral Drug Called A Radiation Sensitizer In Patients With Newly Diagnosed Small Cell Lung Cancer (SCLC)CompletedNCT00043862Phase 2