Tocilizumab: all 334 studies that test it
Page 1 of 4. Open to participants first (53), then studies with results posted, then the rest; newest registration first within each.
- Tocilizumab Combined With First-Line Chemo-Immunotherapy in Metastatic Non-Small Cell Lung CancerNot yet recruitingNCT07889232Phase 1/2
- Infarct Growth After Intravenous Tocilizumab in Adults With Acute Ischemic Stroke Undergoing Endovascular Thrombectomy - ILLUMINATENot yet recruitingNCT07870681Phase 2/3
- Adding Anakinra and Tocilizumab to Nivolumab and Ipilimumab for the Treatment of Melanoma Patients 50 Years of Age or OlderNot yet recruitingNCT07838974Phase 1
- Anticoagulation Combined With Tocilizumab for Interleukin-6 Receptor Inhibition in Acute Cerebral Venous ThrombosisRecruitingNCT07801638Not applicable
- Atezolizumab, Bevacizumab, and Tocilizumab in Advanced Hepatocellular CarcinomaNot yet recruitingNCT07774247Phase 2
- Anti-Interleukin-6 (IL6) in CalciphylaxisNot yet recruitingNCT07708038Phase 1
- Treatment Strategy for Patients With RA-ILDNot yet recruitingNCT07643038Phase 4
- Adult Outpatient Linvoseltamab With Tocilizumab Prophylaxis to Mitigate the Risk of Cytokine Release Syndrome (CRS)RecruitingNCT07609940Phase 4
- Tocilizumab for the Treatment of Refractory Granulomatous Lobular MastitisNot yet recruitingNCT07595900Phase 1/2
- A Study Evaluating the Prophylactic Use of Tocilizumab to Prevent Cytokine Release Syndrome With Ramantamig Administration in Participants With Relapsed/Refractory Multiple MyelomaRecruitingNCT07589634Phase 2
- Efficacy and Safety of Interleukin-6 Receptor Inhibitor Combined With Endovascular Treatment in Patients With Acute Posterior Circulation Large Vessel Occlusion StrokeRecruitingNCT07509645Phase 3
- Neutralizing Interleukin (IL)-6RecruitingNCT07493317Phase 2
- Biologic Treatment Withdrawal in Takayasu Arteritis Patients in Sustained RemissionRecruitingNCT07491913Not applicable
- RCT of Tocilizumab for Anti-MDA5+DMRecruitingNCT07377058Not applicable
- A Study to Compare the Efficacy and Safety of BMS-986353 (Zolacabtagene- Autoleucel / Zola-cel), CD19-CAR T Cells, Versus Standard of Care in Participants With Active Systemic SclerosisNot yet recruitingNCT07335562Phase 3
- Interleukin-6 Guided Treatment With Dexamethasone or Tocilizumab in Patients Hospitalized With Acute Respiratory Symptoms - a Feasibility StudyRecruitingNCT07334379Phase 2
- Tocilizumab in Chronic Inflammatory CPPD DiseaseNot yet recruitingNCT07254637Phase 2
- Immunosuppressant Management in Rheumatology Patients Undergoing Elective Total Shoulder ArthroplastyRecruitingNCT07138898Phase 2
- A Study of Healthy Donor CD19-targeted Allogeneic CAR T Cells in Participants With Severe, Refractory Autoimmune DiseasesRecruitingNCT07115745Phase 1
- Part B- G1X-CGD (Lentiviral Vector Transduced CD34+ Cells) in Patients With X-Linked Chronic Granulomatous DiseaseEnrolling by invitationNCT07113743Phase 1/2
- Tocilizumab Discontinuation Versus Dose Reduction for Patients With Well-Controlled Giant Cell ArteritisRecruitingNCT07108387Phase 2
- Triple-Blind Randomized Clinical Trial of Tocilizumab vs Placebo: Potential Use of an IL-6 Antagonist as an Adjuvant to Standard Treatment for Treatment-Resistant Major Depression in the Brazilian Public Health System (SUS)Not yet recruitingNCT07052058Phase 2
- Treatment of Chronic Active Antibody Mediated Rejection With TocilizumabRecruitingNCT07006532Not applicable
- Pragmatic, Open-Label Study to Pilot Evaluation for Clinical Trials in Relapsing PolychondritisRecruitingNCT06941376Phase 2
- A Study on the Combined Use of Tocilizumab and Flupentixol-Melitracen in the Treatment of Thyroid-Associated OphthalmopathyRecruitingNCT06927375Phase 4
- Tocilizumab-aazg for Hemorrhage: Reduction of Ischemic Vascular EventsRecruitingNCT06863480Phase 1
- Trial of Sequential Medications AfteR TNFi Failure in Juvenile Idiopathic ArthritisRecruitingNCT06654882Phase 3
- Immunomodulatory Effects of Dexamethasone, Tocilizumab and Anakinra During Experimental Human EndotoxemiaRecruitingNCT06624436Phase 4
- A Randomized, Controlled, Open-label, Multicenter Clinical Trial Comparing the Efficacy and Safety of a Precision Treatment Regimen Based on Clinical-molecular Phenotypes with a Conventional Treatment Regimen in the Treatment of Patients with Active Takayasu's ArteritisRecruitingNCT06498089Phase 4
- Interleukin-6 Receptor Inhibition for Symptomatic Intracranial AtherosclerosisNot yet recruitingNCT06447701Phase 3
- Adaptive Platform Trial for Personnalisation of Sepsis Treatment in Children and Adults: a Multi-national, Treatable Traits-guided, Adaptive, Exploratory, Bayesian Basket TrialRecruitingNCT06381661Phase 2
- Study of the Efficacy of Nintedanib+Tocilizumab in Patients With Systemic Sclerosis and Interstitial Lung DiseaseRecruitingNCT06297096Phase 3
- Tocilizumab in Lung TransplantationRecruitingNCT06033196Phase 2
- Tocilizumab Delivered Via Pleural and Peritoneal Catheters in Patients With Advanced Metastatic CancerRecruitingNCT06016179Phase 1
- Outpatient Administration of Teclistamab or Talquetamab for Multiple MyelomaRecruitingNCT05972135Phase 2
- LUSZ Treatment Efficacy in Hospitalized COVID-19 PatientsRecruitingNCT05925140Phase 1
- "Comparison of the Efficacy and Safety of Adalimumab to That of Tocilizumab in Severe Uveitis of Behçet's Disease"Not yet recruitingNCT05874505Phase 2
- Safety and ASCT-related Symptom Burden Optimization of Tocilizumab in ASCT Following HD Melphalan Conditioning for Multiple Myeloma PatientsRecruitingNCT05855122Phase 4
- Tocilizumab and Tofacitinib in the Treatment of Vascular Behçet's SyndromeRecruitingNCT05845723Phase 2
- Open-Label Extension of Tocilizumab in Subjects With Generalized Myasthenia GravisRecruitingNCT05716035Phase 2/3
- Tocilizumab for Acute Chest SyndromeRecruitingNCT05640271Phase 2
- Evaluate the Efficacy and Safety of Various Treatment Schemes for Severe Fever With Thrombocytopenia Syndrome(SFTS)RecruitingNCT05604859Phase 4
- Stand UP to Rheumatoid Arthritis (SUPRA)RecruitingNCT05305066Not applicable
- ACTEMRA® for the Treatment of Pediatric Adamantinomatous CraniopharyngiomaRecruitingNCT05233397Phase 2
- Efficacy and Safety of Tocilizumab in the Treatment of Generalized Myasthenia GravisRecruitingNCT05067348Phase 2
- Study of Salvage Therapy to Treat Patients With Granulomatosis With PolyangiitisRecruitingNCT04871191Phase 3
- Tocilizumab and Atezolizumab in Adults With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Refractory to 1st Line Immune Checkpoint Inhibitor-Based TherapyRecruitingNCT04691817Phase 1/2
- Randomised Evaluation of COVID-19 TherapyRecruitingNCT04381936Phase 3
- Use of Tocilizumab Drug Levels to Optimize Treatment in RARecruitingNCT03895879Phase 4
- A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast CancerRecruitingNCT03424005Phase 1/2
- Abatacept vs Tocilizumab for the Treatment of RA in TNF Alpha Inhibitor Inadequate RespondersRecruitingNCT03227419Phase 4
- Tocilizumab in SchizophreniaRecruitingNCT02874573Phase 1
- Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired PneumoniaRecruitingNCT02735707Phase 3
- A Study to Evaluate the Pharmacokinetics, Safety and Immunogenicity of BIIB800 Subcutaneously (SC) Compared to Actemra® in Healthy Male ParticipantsCompletedNCT06262477Phase 1Results posted
- Testing the Addition of the Immune Therapy Drugs, Tocilizumab and Atezolizumab, to Radiation Therapy for Recurrent GlioblastomaActive, not recruitingNCT04729959Phase 2Results posted
- MSB11456 in Participants With Moderately to Severely Active Rheumatoid ArthritisCompletedNCT04512001Phase 3Results posted
- Low-dose Tocilizumab Versus Standard of Care in Hospitalized Patients With COVID-19TerminatedNCT04479358Phase 2Results posted
- A Study to Evaluate the Efficacy and Safety of Remdesivir Plus Tocilizumab Compared With Remdesivir Plus Placebo in Hospitalized Participants With Severe COVID-19 PneumoniaCompletedNCT04409262Phase 3Results posted
- Tocilizumab for Prevention of Respiratory Failure in Patients With Severe COVID-19 InfectionTerminatedNCT04377659Phase 2Results posted
- Study of Rituximab or Tocilizumab for Patients With Steroid-Dependent Immune-Related Adverse Events (irAEs)Active, not recruitingNCT04375228Phase 2Results posted
- A Study to Evaluate the Efficacy and Safety of Tocilizumab in Hospitalized Participants With COVID-19 PneumoniaCompletedNCT04372186Phase 3Results posted
- Tocilizumab for Patients With Cancer and COVID-19 DiseaseTerminatedNCT04370834Phase 2Results posted
- A Study to Investigate Intravenous Tocilizumab in Participants With Moderate to Severe COVID-19 PneumoniaCompletedNCT04363736Phase 2Results posted
- Efficacy of Tocilizumab on Patients With COVID-19CompletedNCT04356937Phase 3Results posted
- CORIMUNO-19 - Tocilizumab Trial - TOCI (CORIMUNO-TOCI)CompletedNCT04331808Phase 2Results posted
- Tocilizumab to Prevent Clinical Decompensation in Hospitalized, Non-critically Ill Patients With COVID-19 PneumonitisCompletedNCT04331795Phase 2Results posted
- Treatment of COVID-19 Patients With Anti-interleukin DrugsCompletedNCT04330638Phase 3Results posted
- A Study to Evaluate the Safety and Efficacy of Tocilizumab in Patients With Severe COVID-19 PneumoniaCompletedNCT04320615Phase 3Results posted
- Treg Modulation With CD28 and IL-6 Receptor AntagonistsCompletedNCT04066114Phase 1/2Results posted
- A Phase II Study of the Interleukin-6 Receptor Inhibitor Tocilizumab in Combination With Ipilimumab and Nivolumab in Patients With Unresectable Stage III or Stage IV MelanomaActive, not recruitingNCT03999749Phase 2Results posted
- A Study to Evaluate the Pharmacokinetics, Pharmacodynamics, and Safety of Tocilizumab (TCZ) Administered to Participants With Giant Cell Arteritis (GCA).CompletedNCT03923738Phase 1Results posted
- Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatments and Combinations in Patients With Urothelial Carcinoma (MORPHEUS-UC)TerminatedNCT03869190Phase 1/2Results posted
- Tocilizumab Plus a Short Prednisone Taper for GCACompletedNCT03726749Phase 4Results posted
- PROACTIVE: Preventing Acute/Chronic GVHD With TocIlizumab Combined With GVHD Prophylaxis Post allogEneic TransplantCompletedNCT03699631Phase 2Results posted
- Tocilizumab in Cardiac TransplantationCompletedNCT03644667Phase 2Results posted
- Tocilizumab for the Prevention of Graft Versus Host Disease After Cord Blood TransplantationCompletedNCT03434730Phase 2Results posted
- A Study Of Multiple Immunotherapy-Based Treatment Combinations In Participants With Metastatic Non-Small Cell Lung Cancer (Morpheus- Non-Small Cell Lung Cancer)TerminatedNCT03337698Phase 1/2Results posted
- A Study of Multiple Immunotherapy-Based Treatment Combinations in Participants With Metastatic Pancreatic Ductal Adenocarcinoma (Morpheus-Pancreatic Cancer)CompletedNCT03193190Phase 1/2Results posted
- Tocilizumab Real-Life Human Factors (RLHFs) Validation StudyCompletedNCT02682823Phase 4Results posted
- Tocilizumab Augmentation in Treatment-Refractory Major Depressive DisorderTerminatedNCT02660528Phase 2Results posted
- Effect of Subcutaneous ACTEMRA on Inflamed Atherosclerotic Plaques in Patients With Rheumatoid ArthritisTerminatedNCT02659150Phase 4Results posted
- Study to Compare the Efficacy of Tocilizumab With or Without Glucocorticoid Discontinuation in Rheumatoid Arthritis ParticipantsCompletedNCT02573012Phase 4Results posted
- A Trial of Tocilizumab in ALS SubjectsCompletedNCT02469896Phase 2Results posted
- A Study of the Efficacy and Safety of Tocilizumab in Participants With Systemic Sclerosis (SSc)CompletedNCT02453256Phase 3Results posted
- Short-Term Application of Tocilizumab Following Myocardial InfarctionCompletedNCT02419937Not applicableResults posted
- Alemtuzumab or Tocilizumab in Combination With Etoposide and Dexamethasone for the Treatment of Adult Patients With Hemophagocytic LymphohistiocytosisCompletedNCT02385110Phase 2Results posted
- Mechanistic Studies of B- and T-Cell Function in RA Patients Treated With TNF Antagonists, Tocilizumab, or AbataceptTerminatedNCT02353780Phase 4Results posted
- Study Evaluating the Safety and Efficacy of KTE-C19 in Adult Participants With Refractory Aggressive Non-Hodgkin LymphomaCompletedNCT02348216Phase 1/2Results posted
- Tocilizumab (TCZ) in New-onset Type 1 DiabetesCompletedNCT02293837Phase 2Results posted
- A Study of Tacrolimus/Methotrexate and Tocilizumab to Prevent Acute Graft-Versus-Host Disease (AGVD) After Allogeneic Hematopoietic Stem Cell TransplantCompletedNCT02206035Phase 2Results posted
- Tocilizumab for Renal Graft InflammationCompletedNCT02108600Phase 2Results posted
- AIDS 347: IL-6 Blockade in Treated HIV InfectionCompletedNCT02049437Phase 1/2Results posted
- A Study of Subcutaneous (SC) Tocilizumab (RoActemra/Actemra) in Participants With Active Rheumatoid Arthritis (RA) and Inadequate Response to Disease-Modifying Anti-Rheumatic Drugs (DMARDs)CompletedNCT02046616Phase 3Results posted
- Tocilizumab in the Treatment of Refractory Polymyositis and DermatomyositisCompletedNCT02043548Phase 2Results posted
- Tocilizumab as Add-On Treatment For Residual Positive, Negative, and Cognitive Symptoms of SchizophreniaCompletedNCT02034474Phase 4Results posted
- TOSCARA Study: A Study of Subcutaneous Tocilizumab (RoActemra/Actemra) in Participants With Active Rheumatoid Arthritis Naïve to RoActemra/Actemra TreatmentCompletedNCT02031471Phase 3Results posted
- A Study of RoActemra/Actemra (Tocilizumab) in Adult Patients With Rheumatoid Arthritis (SVOBODA Programme)CompletedNCT02010216Phase 4Results posted
- A Study of Tocilizumab (RoActemra) in Tocilizumab-Naive Participants With Rheumatoid Arthritis and Inadequate Response to Non-Biologic Disease-Modifying Antirheumatic Drugs (DMARDs) and/or Biologic TherapyCompletedNCT02001987Phase 3Results posted
- A Study of Subcutaneous RoActemra/Actemra (Tocilizumab) as Monotherapy or in Combination With Methotrexate or Other Non-Biologic DMARDs in Patients With Active Rheumatoid ArthritisCompletedNCT01995201Phase 3Results posted
- A Pharmacodynamic Study to Evaluate Neutrophil Distribution Kinetics and Function Following Single-Dose RoActemra/Actemra (Tocilizumab) in Healthy VolunteersCompletedNCT01991990Phase 4Results posted