Tamoxifen: all 215 studies that test it

Page 1 of 3. Open to participants first (25), then studies with results posted, then the rest; newest registration first within each.

• Clinical Trial to Observe the Effects of Tamoxifen on Testosterone Recovery in Medically Castrated Prostate Cancer PatientsRecruitingNCT07535905Phase 2
• Randomized Double-Blind Phase II Trial of Baby Exemestane Versus Baby Tamoxifen in Post-Menopausal Women at High Risk for Breast CancerNot yet recruitingNCT07499999Phase 2
• Early Study on Tamoxifen Safety/Tolerability in Cystic Fibrosis Patients Unable to Use CFTR Modulators.Not yet recruitingNCT07289035Phase 2
• A Study of MK-5684 in People With Certain Solid Tumors (MK-5684-015/OMAHA-015)RecruitingNCT06979596Phase 2
• Tamoxifen for Advanced Solid Pseudopapillary Tumor of the PancreasRecruitingNCT06914674Phase 2
• A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of RecurrenceRecruitingNCT06492616Phase 3
• Tamoxifen and Pegylated Liposomal Doxorubicin for the Treatment of Patients With Metastatic or Inoperable, Locally Advanced Triple Negative Breast CancerRecruitingNCT06434064Phase 2
• Low Dose Exemestane vs Low Dose Tamoxifen in Post-menopausal Women at High Risk for Breast Cancer.RecruitingNCT06364267Phase 2
• Maintenance Hormonal Therapy and DLBCLNot yet recruitingNCT06355401Phase 2/3
• Assessing the Efficacy and Safety of Anti-HER2 Therapy in Nigerian Women With HER2+ Breast Cancer Before and After SurgeryRecruitingNCT06348134Phase 2
• Chemoprevention With Tamoxifen in Pre-Invasive Pancreas Mucinous Cystic Neoplasms Not Undergoing Immediate ResectionRecruitingNCT06320990Phase 1
• Optimizing Extended Adjuvant Endocrine Therapy in Patients With Breast CancerNot yet recruitingNCT06223698Phase 3
• Finding the Best Tamoxifen Dose for Breast Cancer Risk Reduction in Premenopausal Women, RENAISSANCE TrialRecruitingNCT06184750Phase 2
• Safety Extension Study for Subjects With HR+, HER2- Breast Cancer for Subjects Who Have Completed the OVELIA StudyEnrolling by invitationNCT05645536Phase 3
• Tamoxifen Prediction Study in Patients With ER+ Breast CancerRecruitingNCT05525481Phase 4
• ETHAN - ET for Male BCRecruitingNCT05501704Phase 2
• Tamoxifen Versus Etoposide After First Recurrence in GBM PatientsRecruitingNCT04765098Phase 2
• Impact of Neoadjuvant Hormonal Therapy on the Surgical Management of Extensive Ductal Carcinomas in SituRecruitingNCT04666961Phase 2
• FES Imaging to Optimize Tamoxifen for Metastatic Breast CancerRecruitingNCT04174352Early Phase 1
• Radiotherapy Versus Low-Dose Tamoxifen Following Breast Conserving Surgery for Low-Risk Breast Ductal Carcinoma in SituRecruitingNCT04046159Phase 3
• A Window of Opportunity Study of Pre-operative Endocrine Therapy With and Without Prometrium in Postmenopausal Women With Early Stage Breast Hormone Receptor Positive (HR+) Human Epidermal Receptor 2 Negative (HER2-) Breast Cancer.RecruitingNCT03906669Phase 2
• Efficacy of Tamoxifen Versus Toremifene in CYP2D6 IM/PM of Premenopausal Patients With ER-positive Early Breast CancerRecruitingNCT03351062Phase 3
• Fertility Preservation Using Tamoxifen and Letrozole in Estrogen Sensitive Tumors TrialRecruitingNCT03011684Phase 3
• Endocrine Treatment Alone for Elderly Patients With Estrogen Receptor Positive Operable Breast Cancer and Low Recurrence ScoreRecruitingNCT02476786Phase 2
• Evaluation of Tamoxifen's Efficacy for ER/PR Negative,ER-beta Positive Operable Breast Cancer PatientsRecruitingNCT02062489Phase 3
• A Precision Medicine Approach (SMMART-ACT) for the Treatment of Patients With Advanced Sarcoma, Prostate, Breast, Ovarian or Pancreatic CancerTerminatedNCT06630325Phase 2Results posted
• Study of Intravaginal Tamoxifen in PostMenopausal Women With VVACompletedNCT05378269Phase 1/2Results posted
• Umbrella Trial of Subtype-Targeted Therapies in ER+/HER2- Breast CancerCompletedNCT05101564Phase 2Results posted
• Oral Tamoxifen vs. TamGel vs. Control in Women With Atypical Hyperplasia, Lobular Carcinoma In Situ, or Increased Breast Cancer RiskTerminatedNCT04570956Phase 2Results posted
• Study of Infigratinib in Combination With Tamoxifen in Hormone Receptor Positive, HER2 Negative, FGFR Altered Advanced Breast CancerTerminatedNCT04504331Phase 1Results posted
• The Effects of Short-term Preoperative Treatment With Hormonal Therapy on Gene Profiles in Breast CancerCompletedNCT04129216Phase 2Results posted
• Karolinska Interventional Study of Mammograhic Density (Karisma-1)CompletedNCT04079517Phase 1/2Results posted
• Tamoxifen Therapy to Treat Pulmonary Arterial HypertensionCompletedNCT03528902Phase 2Results posted
• Selective Estrogen Receptor Modulators to Enhance the Efficacy of Viral Reactivation With Histone Deacetylase InhibitorsCompletedNCT03382834Phase 2Results posted
• Low Dose Tamoxifen for Mammographic Density ReductionCompletedNCT03346200Phase 2Results posted
• A Study of Multiple Immunotherapy-Based Treatment Combinations in Hormone Receptor (HR)-Positive Human Epidermal Growth Factor Receptor 2 (HER2)-Negative Breast CancerCompletedNCT03280563Phase 1/2Results posted
• Neoadjuvant Endocrine Therapy in Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2 (HER2)-Negative Node-Negative Breast CancerCompletedNCT03219476Phase 2Results posted
• Efficacy of High Dose Tamoxifen to Advanced Hormone Receptor-High Expressed Breast CancerCompletedNCT03045653Phase 2Results posted
• TAK-228 Plus Tamoxifen in Patients With ER-Positive, HER2-negative Breast CancerCompletedNCT02988986Phase 2Results posted
• Impact of Low-dose Tamoxifen on BPUCompletedNCT02979301Not applicableResults posted
• Treatment of Metastatic Breast Cancer With Fulvestrant Plus Palbociclib or Tamoxifen Plus PalbociclibCompletedNCT02913430Early Phase 1Results posted
• Treatment of Unfavorable Bleeding Patterns in Contraceptive Implant UsersCompletedNCT02903121Phase 4Results posted
• Tamoxifen to Reduce Unscheduled Bleeding in New Users of the Levonorgestrel-releasing Intrauterine System (LNG-IUS)CompletedNCT02824224Phase 4Results posted
• Neoadjuvant Tamoxifen in Locally Advanced Breast Cancer in a Low/Middle Income CountryCompletedNCT02806544Phase 2Results posted
• A Study of Abemaciclib (LY2835219) Plus Tamoxifen or Abemaciclib Alone in Women With Metastatic Breast CancerCompletedNCT02747004Phase 2Results posted
• Palbociclib in Combination With Tamoxifen as First Line Therapy for Metastatic Hormone Receptor Positive Breast CancerCompletedNCT02668666Phase 2Results posted
• TEEL Study- Phase 1 Tamoxifen and Ribociclib (LEE011) in Advanced ER+ (HER2 Negative) Breast CancerCompletedNCT02586675Phase 1Results posted
• Reversing Therapy Resistance With Epigenetic-Immune ModificationTerminatedNCT02395627Phase 2Results posted
• A Study of Palbociclib in Combination With Fulvestrant or Tamoxifen as Treatment for Metastatic Breast CancerCompletedNCT02384239Phase 2Results posted
• Tamoxifen Citrate or Z-Endoxifen Hydrochloride in Treating Patients With Locally Advanced or Metastatic, Estrogen Receptor-Positive, HER2-Negative Breast CancerActive, not recruitingNCT02311933Phase 2Results posted
• Endocrine Response in Women With Invasive Lobular Breast CancerCompletedNCT02206984Phase 2Results posted
• Evaluation the Treatment of Tamoxifen of Low/Intermediate Risk Bladder TumorsCompletedNCT02197897Phase 2Results posted
• To Assess Safety and Effect of Olaparib on the Pharmacokinetics of Anastrozole, Letrozole & Tamoxifen, and Their Effect on Olaparib, in Patients With Advanced Solid CancerCompletedNCT02093351Phase 1Results posted
• Tamoxifen for the Treatment of Unfavorable Bleeding in Contraceptive Implant UsersCompletedNCT02070692Phase 4Results posted
• Preoperative Hormone Therapy for Postmenopausal Women With ER+ Clinical Stage T2-4 TumorsCompletedNCT01831076Phase 2Results posted
• Preoperative Window of Endocrine Therapy Provides Information to Increase ComplianceCompletedNCT01614210Phase 2Results posted
• Hormone Therapy Or Chemotherapy Before Surgery Based on Gene Expression Analysis in Treating Patients With Breast CancerCompletedNCT01293032Not applicableResults posted
• Safety and Efficacy Study of Creatine and Tamoxifen in Volunteers With Amyotrophic Lateral Sclerosis (ALS)CompletedNCT01257581Phase 2Results posted
• Low-Dose Tamoxifen Citrate in Reducing Breast Cancer Risk in Radiation-Induced Cancer SurvivorsActive, not recruitingNCT01196936Phase 2Results posted
• Re-expression of ER in Triple Negative Breast CancersTerminatedNCT01194908Phase 1/2Results posted
• A Study of Vorinostat and Tamoxifen in Newly Diagnosed Breast CancerTerminatedNCT01194427Phase 2Results posted
• Open-Label Drug Interaction Study Evaluating Desvenlafaxine Succinate Sustained Release (DVS SR) 100mg On The Pharmacokinetics Of Tamoxifen When Coadministered To Healthy Post-Menopausal Female SubjectsCompletedNCT01189500Phase 4Results posted
• Tamoxifen Citrate in Treating Patients With Metastatic or Recurrent Breast CancerCompletedNCT01124695Phase 2Results posted
• Analyzing a New Mechanism in Response to Tamoxifen Therapy in Breast Cancer PatientsCompletedNCT01027416Not applicableResults posted
• Effects of Tamoxifen in Premenopausal Women With Benign Breast Disease Not at High-Risk of Developing Breast CancerCompletedNCT00999921Phase 4Results posted
• Studying Blood Samples From Women With Breast Cancer or Ductal Carcinoma In Situ Who Are Receiving TamoxifenCompletedNCT00764322Phase 2Results posted
• Temsirolimus With or Without Megestrol Acetate and Tamoxifen Citrate in Treating Patients With Advanced, Persistent, or Recurrent Endometrial CancerCompletedNCT00729586Phase 2Results posted
• Tamoxifen for Progressive Transitional Cell Carcinoma Following Previous Chemotherapy TreatmentCompletedNCT00710970Phase 2Results posted
• Cognition in the Study of Tamoxifen and RaloxifeneCompletedNCT00687102Phase 3Results posted
• Brain Function in Premenopausal Women Receiving Tamoxifen With or Without Ovarian Function Suppression for Early-Stage Breast Cancer on Clinical Trial IBCSG 24-02CompletedNCT00659373Phase 3Results posted
• Phase II Trial of SAHA & Tamoxifen for Patients With Breast CancerCompletedNCT00365599Phase 2Results posted
• Tamoxifen Versus Anastrozole, Alone or in Combination With Zoledronic AcidCompletedNCT00295646Phase 3Results posted
• Luteal vs Follicular Surgical Oophorectomy and Tamoxifen in Premenopausal Women With Metastatic Hormone Receptor Positive Breast CancerCompletedNCT00293540Phase 3Results posted
• Tamoxifen or Letrozole in Treating Women With Ductal Carcinoma in SituCompletedNCT00290745Phase 1/2Results posted
• Internal Radiation Therapy After Lumpectomy in Treating Women With Ductal Carcinoma in SituTerminatedNCT00290654Phase 2Results posted
• Adjuvant Oophorectomy and Tamoxifen in Premenopausal Women With Hormone Receptor-Positive Breast CancerCompletedNCT00201851Phase 3Results posted
• A Pilot Clinical Trial to Evaluate the Biological Activity of Fulvestrant in Breast Ductal Carcinoma in Situ (DCIS)TerminatedNCT00183963Phase 2Results posted
• A Study to Evaluate the Effect of Letrozole and Tamoxifen on Bone and Lipids in Postmenopausal Women With Breast CancerCompletedNCT00171704Phase 3Results posted
• Lapatinib and Tamoxifen in Treating Patients With Locally Advanced or Metastatic Breast Cancer That Did Not Respond to Previous TamoxifenCompletedNCT00118157Phase 2Results posted
• Tamoxifen and Bortezomib to Treat Recurrent Brain TumorsCompletedNCT00108069Phase 2Results posted
• Adjuvant Tamoxifen Compared With Anastrozole in Treating Postmenopausal Women With Ductal Carcinoma In SituCompletedNCT00072462Phase 3Results posted
• Sulindac and Tamoxifen in Treating Patients With Desmoid TumorCompletedNCT00068419Phase 2Results posted
• Suppression of Ovarian Function With Either Tamoxifen or Exemestane Compared With Tamoxifen Alone in Treating Premenopausal Women With Hormone-Responsive Breast CancerCompletedNCT00066690Phase 3Results posted
• Tamoxifen Compared With Thalidomide in Treating Women With Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal CancerCompletedNCT00041080Phase 3Results posted
• Randomized Phase III Study Of Exemestane (Aromasin) For 5 Years Versus Tamoxifen for 2.5 to 3 Years Followed By ExemestaneCompletedNCT00036270Phase 3Results posted
• SHORTened Duration of TAMoxifenActive, not recruitingNCT07806630Phase 2
• Letrozole vs. Clomiphene Citrate Plus Tamoxifen for Ovulation Induction and Pregnancy Outcomes.Active, not recruitingNCT07616973Phase 3
• Safety, Efficacy and Pharmacokinetic Behavior of Leuprolide Injectable Emulsion for Premenopausal Breast Cancer Subjects.Active, not recruitingNCT06449027Phase 3
• Low Dose TamOxifen and LifestylE Changes for bReast cANcer prevenTionCompletedNCT06033092Phase 2
• Clinical Study on Adjuvant Therapy of TQB3616 Combined With Endocrine Therapy Compared With Placebo Combined With Endocrine Therapy in Patients With Breast CancerActive, not recruitingNCT05780567Phase 3
• Study on the Efficacy and Toxicity of Pamiparib Combined With Tamoxifen in the Treatment of Epithelial Ovarian Cancer Patients With Biochemical Recurrence During First-line PARPi Maintenance TherapyStatus unknownNCT05669768Phase 2
• CYP2D6 Genotypes and Breast Cancer Clinical Outcomes in the Indonesian PopulationStatus unknownNCT05501158Not applicable
• Tamoxifen and SUBA-Itraconzole Combination Testing in Ovarian CancerActive, not recruitingNCT05156892Phase 1
• Neoadjuvant Endocrine Therapy in ER-positive, HER2-negative Early Stage Breast CancerCompletedNCT05150652Phase 2
• Therapeutic Dose Monitoring (TDM) of TamoxifenStatus unknownNCT05133674Phase 2
• Investigating the Potential Role of a Novel Quadrate Combination Therapy Mifepristone(Antiprogestrone), Tamoxifen, Retinoic Acid and Cannabidiol ( Selective Cyp 26 Inhibitor) for Treating Early Breast Cancer.Status unknownNCT05016349Phase 3
• Higher Dose Preoperative taMOxifen in Premenopausal bREast Cancer PatientsActive, not recruitingNCT04997941Phase 2
• Dose-determining and Dose-confirmatory Study to Investigate the Optimal Dose of Tamoxifen in Breast Cancer Patients According to Genotype Status of TCF20 rs932376Active, not recruitingNCT04961632Phase 1
• Tamoxifen Versus Estradiol for Unscheduled Bleeding in Etonogestrel Implant Users, a Randomized Pilot TrialWithdrawnNCT04933240Phase 4
• Tamoxifen Therapy for Myotubular MyopathyTerminatedNCT04915846Phase 1/2

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