Serotonin and Noradrenaline Reuptake Inhibitors: all 504 studies that test it

Page 3 of 6. Open to participants first (35), then studies with results posted, then the rest; newest registration first within each.

• Pilot Study of Duloxetine in Psychological ResilienceCompletedNCT00331799Phase 2Results posted
• Maintenance of Effect of Duloxetine in Patients With Diabetic Peripheral Neuropathic Pain (DPNP)CompletedNCT00322621Phase 4Results posted
• Study of Milnacipran for the Treatment of FibromyalgiaCompletedNCT00314249Phase 3Results posted
• Improving Treatment Outcomes in Pharmacotherapy of Generalized Social Anxiety DisorderCompletedNCT00282828Phase 4Results posted
• Psychosocial and Medication Treatment for Anxiety in AlcoholismCompletedNCT00248612Phase 2/3Results posted
• CBT as an Adjunct to SRIs in the Treatment of BDDTerminatedNCT00211809Phase 4Results posted
• Evaluation of Depression Symptoms and Brain Activity Associated With Response to Treatment of DepressionCompletedNCT00200902Phase 4Results posted
• Effectiveness of Long-Term Versus Short-Term Treatment of Generalized Anxiety Disorder With Venlafaxine XRCompletedNCT00183274Phase 4Results posted
• Free Venlafaxine Treatment for Marijuana Addiction and Depression - 1CompletedNCT00131456Phase 2Results posted
• Duloxetine for Social Anxiety Disorder: Prediction of Long Term OutcomeCompletedNCT00114127Phase 3Results posted
• Duloxetine Versus Placebo in the Prevention of Recurrence of Major Depressive DisorderCompletedNCT00105989Phase 3Results posted
• Study of Antidepressants in Parkinson's DiseaseCompletedNCT00086190Phase 3Results posted
• Treatments for Depression: Drug Versus PsychotherapyCompletedNCT00043550Phase 3Results posted
• Dose Optimization of Sitagliptin and Duloxetine in Diabetic CirrhosisCompletedNCT07439536Phase 4
• Desvenlafaxine for Preventive Treatment of Frequent MigrainesActive, not recruitingNCT07385755Not applicable
• Desvenlafaxine for Preventive Treatment of Frequent Episodic Tension-type HeadacheActive, not recruitingNCT07359248Not applicable
• Efficacy and Safety Study of Levomilnacipran Hydrochloride Extended-Release Capsules in Major Depressive DisorderCompletedNCT07253207Phase 3
• Duloxetine to Prevent Chronic Postsurgical Pain After Inguinal Hernia Repair in Patients at High RiskActive, not recruitingNCT06606067Phase 3
• Evaluating the Efficacy and Safety of Preoperative Administration of Duloxetine for Pain Management in Women Undergoing Hysterectomy Via Vaginal RouteCompletedNCT06429605Not applicable
• Pharmacological Treatment Targeting Endotypic Traits of Obstructive Sleep ApneaCompletedNCT06295562Phase 4
• Pain Relieving Potentials of Combination of Oral Duloxetine and Intravenous Magnesium Sulphate in Post Mastectomy PainCompletedNCT06087211Not applicable
• Venlafaxine for the Prevention of Depression in Patients With Head and Neck CancerWithdrawnNCT05724849Phase 2
• Medicine-induced Cardiac Hemodialysis on COVID-19CompletedNCT05711810Phase 4
• Therapeutic Efficacy in Women With Stress Urinary IncontinenceStatus unknownNCT05677295Phase 3
• Duloxetine Impact on Postoperative Pain Control and OutcomesTerminatedNCT05611749Phase 2
• Treatment of Withdrawal Symptoms and Prevention of Relapse in Patients With Tramadol AbuseCompletedNCT05569031Phase 4
• Efficacy of Duloxetine Compared to NSIADs in Osteoarthritis of KneeCompletedNCT05486026Phase 2
• Effect of Milnacipran / Gabapentin in FibromyalgiaStatus unknownNCT05384210Not applicable
• Efficacy of Duloxetine in Conjunction With Tramadol for Chronic Cancer PainCompletedNCT05311774Not applicable
• Botulinum Toxin Type A in Diabetic Peripheral NeuropathyCompletedNCT05296759Phase 4
• Efficacy of Pregabalin Vs Duloxetine in Diabetic Peripheral Neuropathic Pain at Variable DoseStatus unknownNCT05292066Early Phase 1
• Predictors of Cognitive Outcomes in Geriatric DepressionActive, not recruitingNCT05273996Phase 4
• Biomarkers for Prediction of Analgesic Efficacy in Knee OA.CompletedNCT05256342Not applicable
• Duloxetine for Postoperative Pain of Laparoscopic CholecystectomyCompletedNCT05115123Phase 2
• Duloxetine RCT on Postop TKA OutcomesCompletedNCT05086393Phase 4
• Microbiome Derived Metabolism and PharmacokineticsCompletedNCT05065671Phase 1
• Oral Duloxetine as a Premedication for Postoperative Pain ControlCompletedNCT05050656Phase 4
• The Use of Venlafaxine in Reducing Pain in Primary Total Knee ReplacementCompletedNCT05023278Phase 4
• Mood Disorders in Head and Neck Cancer PatientsWithdrawnNCT04977271Phase 4
• Feasibility Trial of Tele-IPT and Tele-Pharmacotherapy for Patients With Depression and Non-Metastatic Breast CancerSuspendedNCT04973930Phase 3
• Combination of Duloxetine and Pregabalin to Improve Postoperative PainCompletedNCT04862845Phase 1
• Duloxetine vs Pregabalin for Thoracotomy PainStatus unknownNCT04782310Phase 4
• Bioavailability of Duloxetine 60 mg With Regards to Reference Product in Feeding ConditionsCompletedNCT04751318Phase 1
• The Potential Protective Role of Venlafaxine Versus Memantine in Paclitaxel Induced Peripheral NeuropathyStatus unknownNCT04737967Phase 2/3
• Lidocaine Versus Duloxetine for the Prevention of Taxane-Induced Peripheral Neuropathy In Breast Cancer PatientsCompletedNCT04732455Not applicable
• Comparison of Duloxetine Versus PregabalinStatus unknownNCT04727502Phase 2
• Bioavailability of Duloxetine 60 mg With Regards to Reference Product in Fasting ConditionsCompletedNCT04723238Phase 1
• Neuroimaging Guided and Robot-assisted rTMS for Suicidal Ideation of DepressionStatus unknownNCT04653337Phase 2
• Duloxetine Tibial PlateauWithdrawnNCT04639011Phase 4
• Duloxetine and Neurofeedback Training for the Treatment of Chemotherapy Induced Peripheral NeuropathyActive, not recruitingNCT04560673Phase 2
• Comparison of the Efficacy of Duloxetine and Pregabalin in Patients With Knee Osteoarthritis With Mix Type PainCompletedNCT04532684Phase 4
• Optimization of Diagnosis and Treatment of Depression Based on Multidimensional Clinical Assessment ClassificationStatus unknownNCT04528628Not applicable
• A Sequenced Strategy for Improving Outcomes in People With Knee Osteoarthritis PainCompletedNCT04504812Phase 3
• Efficacy of Online CBT for GAD Compared to Pharmaceutical InterventionsCompletedNCT04478526Not applicable
• Comparisons of the Impact of Duloxetine Versus Imipramine on Therapeutic Efficacy, Psychological Distress, Sexual Function, Urethral and Bladder Wall Structure and Blood Flow in Women With Stress Urinary Incontinence: a Randomized Controlled StudyWithdrawnNCT04412876Phase 3
• Leveraging EEG for Antidepressant Prediction With Duloxetine and BupropionWithdrawnNCT04388189Phase 4
• Duloxetine for PHNCompletedNCT04313335Not applicable
• Efficacy of Perioperative Duloxetine as a Part of Multimodal Analgesia in Laparoscopic Colorectal Cancer SurgeryStatus unknownNCT04294953Phase 2
• Efficacy of Pregabalin and Duloxetine in Patients With PDPN: the Effect of Pain on Cognitive Function, Sleep and Quality of LifeTerminatedNCT04246619Phase 4
• A Mechanism Based Proof of Concept Study of the Effects of Duloxetine in the Treatment of Patients With Osteoarthritic Knee PainCompletedNCT04224584Phase 2
• A Study of Individualized Diagnosis and Treatment for Major Depressive Disorder With Atypical FeaturesStatus unknownNCT04209166Not applicable
• Duloxetine to Prevent Oxaliplatin-Induced Peripheral Neuropathy in Patients With Stage II-III Colorectal CancerActive, not recruitingNCT04137107Phase 2/3
• Duloxetine Combined With Intra-articular Injection of Corticosteroid and Hyaluronic Acid Reduces Pain in the Treatment of Knee Osteoarthritis PatientsCompletedNCT04117893Phase 4
• Exercise Plus Duloxetine for Knee OsteoarthritisCompletedNCT04111627Phase 2
• Effects of Duloxetine on Postoperative Wound Complication of Total Knee Arthroplasty (TKA) in Central Sensitization PatientsStatus unknownNCT03880916Not applicable
• A Study Of Duloxetine Hydrochloride Hard Gelatinous Capsule Compared To Cymbalta Under Fed ConditionsWithdrawnNCT03794154Phase 4
• Pre-emptive Effect of Duloxetine in the Second Knee in Staged Total Knee ArthroplastyStatus unknownNCT03792828Phase 4
• A Study of LY03005 vs PristiqCompletedNCT03733574Phase 1
• A Study of Duloxetine Hydrochloride Hard Gelatinous Capsule Compared To CymbaltaWithdrawnNCT03729284Phase 4
• A Prediction Study of Multiple Indexes of the Effect of Different Mechanisms of Antidepressants Treatment on DepressionStatus unknownNCT03623711Early Phase 1
• Duloxetine Role in Reducing Opioid Consumption After ThoracotomyCompletedNCT03618225Phase 4
• Duloxetine Potentiates the Analgesic Efficacy of Intrathecal MorphineCompletedNCT03560427Not applicable
• Analgesic Efficacy of Duloxetine in Patients Undergoing Lumbar DiscectomyStatus unknownNCT03549026Not applicable
• Duloxetine for Acute Post-mastectomy PainCompletedNCT03468348Not applicable
• Relative Bioavailability (RBA) Study of LY03005 vs Pristiq®CompletedNCT03357796Phase 1
• Perioperative Duloxetine for Pain Management After Laparoscopic HysterectomyCompletedNCT03350334Not applicable
• 'Fix the Dysfunction' Concept for Mechanism-based Pharmacological Treatment of Neuropathic Pain by DrugCompletedNCT03276689Not applicable
• A Proof of Concept Study of the Prevention of Mild Cognitive Impairment and Eventual Alzheimer's Disease Using F18 FlutemetamolTerminatedNCT03274817Phase 1
• Levomilnacipran in Healthy MalesStatus unknownNCT03249311Phase 4
• Duloxetine for Post Laparoscopic Shoulder PainCompletedNCT03249168Phase 3
• Multi-Dimensional Diagnosis,Individualized Therapy,and Management Technique for Major Depressive Disorder:Based on Clinical and Pathological CharacteristicsStatus unknownNCT03219008Phase 4
• A Diagnosis and Treatment Optimization Study of Depression Based on the Neurological Mechanism of Reward SystemStatus unknownNCT03148522Not applicable
• Efficacy and Safety of Duloxetine Among Individuals With Depressive Disorder in a 12 Weeks TrialCompletedNCT03121573Not applicable
• Short-term Efficacy of Antidepressant in Patients Underwent TKAStatus unknownNCT03110172Phase 1/2
• Neurobiology of Treatment Responses in MDDWithdrawnNCT03068247Phase 3
• Impact of Genetic Polymorphism on Drug-Drug Interactions Involving CYP2D6CompletedNCT03054220Not applicable
• Duloxetine for Succinylcholine-induced Postoperative MyalgiaCompletedNCT03037073Phase 2/3
• CAMH - McMaster Collaborative Care Initiative For Mental Health Risk Factors In DementiaCompletedNCT02955719Not applicable
• Treatment Outcome in Major Depressive DisorderCompletedNCT02869035Phase 1
• Dimensional Approach to Evaluate Reward Processing in Major Depressive Disorder Pre- and Post-Desvenlafaxine TreatmentCompletedNCT02859103Phase 4
• A Multidisciplinary Approach to Manage Gait Difficulty in Parkinson PatientsWithdrawnNCT02857244Phase 2
• Determination of the Antidepressant Duloxetine in Plasma to Improve the Knowledge of the Analgesic Action of Antidepressants on Chronic Neuropathic PainCompletedNCT02846701Phase 4
• Desvenlafaxine for Treatment of Hot Flashes in Women With Breast Cancer Taking TamoxifenTerminatedNCT02819921Phase 4
• Methylphenidate-Duloxetine Combinations for Cocaine DependenceCompletedNCT02700711Phase 1
• Shifting Pain Modulation From Pro-to Anti-nociceptiveTerminatedNCT02672202Not applicable
• A Study to Assess The Effects Of Effexor XR On Cardiac Repolarization In Healthy Adult SubjectsCompletedNCT02637193Phase 1
• Effects of Duloxetine on Pain Relief After Total Knee Arthroplasty in Central Sensitization PatientStatus unknownNCT02600247Not applicable
• The Use of Duloxetine for Cognition Improvement in Individuals With Mild Cognitive ImpairmentCompletedNCT02590874Phase 4
• Newer Antidepressants in Combination With Pregabalin for Fibromyalgia SyndromeCompletedNCT02451475Phase 1/2
• The Effect of Duloxetine on Mood, Quality of Life and Cognitive Functioning in Glioblastoma PatientsTerminatedNCT02443194Phase 3

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